Cell Migration Inhibition (definition)

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ψ	Cell Migration Inhibition

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Definition: Phenomenon of cell-mediated immunity measured by in vitro inhibition of the migration or phagocytosis of antigen-stimulated LEUKOCYTES or MACROPHAGES. Specific CELL MIGRATION ASSAYS have been developed to estimate levels of migration inhibitory factors, immune reactivity against tumor-associated antigens, and immunosuppressive effects of infectious microorganisms.

coordinate with specific cell/immunol; do not confuse with LEUKOCYTE ADHERENCE INHIBITION TEST
See Also Cell Migration Assays; Leukocyte Migration-Inhibitory Factors; Macrophage Migration-Inhibitory Factors

Other names Inhibitions, Chemotaxis; Inhibition, Chemotaxis; Chemotaxis Inhibitions; Chemotaxis Inhibition

Substance	Categories	Source
efalizumab	*Antibodies, Monoclonal Cell Migration Inhibition Antigens, CD11.	Transpl Immunol 2002 May;9(2-4):181-6	RAPTIVA
natalizumab	*Antibodies, Monoclonal, Humanized Cell Migration Inhibition Multiple Sclerosis Integrin alpha4.	Nervenarzt 2002 Jun;73(6):552-5	TYSABRI
fibroblast migration inhibitory factor	*Lymphokines Cell Migration Inhibition.	Cell Immunol 1982;74(1):104

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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