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Ceramides

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Definition: Members of the class of neutral glycosphingolipids. They are the basic units of SPHINGOLIPIDS. They are sphingoids attached via their amino groups to a long chain fatty acyl group. They abnormally accumulate in FABRY DISEASE.  carbohydrate ceramides: index under CEREBROSIDES (one carbohydrate group) or NEUTRAL GLYCOSPHINGOLIPIDS (more than one carbohydrate group)   
See Also Fabry Disease
Examples Cerebrosides; Globosides; Lactosylceramides; Trihexosylceramides
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
clavaminol C  0   *Ceramides. Org Biomol Chem. 2011 Dec 7;9(23):8030-7
clavaminol A  0   *Ceramides. Org Biomol Chem. 2011 Dec 7;9(23):8030-7
bathymodiolamide A  0   *Ceramides. J Nat Prod. 2011 Apr 25;74(4):842-6
bathymodiolamide B  0   *Ceramides. J Nat Prod. 2011 Apr 25;74(4):842-6
(2S, 3S, 4R, 20E)-2-((2'R)-2'-hydroxyl-palmitoyl-amino)-20-hexacosene-1, 3, 4-triol  0   *Ceramides. Fitoterapia. 2010 Jul;81(5):339-42
clavaminol H  0   *Ceramides. J Org Chem 2010 Aug 6;75(15):5312-5
N-stearoylphytosphingosine  0   *Ceramides. Lipids 2010 Jul;45(7):613-8
(E)-N-(1,3,4,5-tetrahydroxyhexadecan-2-yl)dec-4-enamide  0   *Ceramides. J Asian Nat Prod Res. 2010 Aug;12(8):702-6
cameroonemide A  0   *Ceramides. J Asian Nat Prod Res. 2010 Jul;12(7):629-33
(2S,3R,4E)-2-(14'-methyl-pentadecanoylamino)-4-octadecene-l,3-diol  0   *Ceramides. J Asian Nat Prod Res. 2009 Sep;11(9):1005-12
PCERA-1  0   *Ceramides. Immunology 2009 May;127(1):103-15
SLE66 compound  0   *Ceramides. Food Chem Toxicol 2009 Apr;47(4):669-73
EpiCeram  0   *Ceramides *Cholesterol *Fatty Acids Drug Combinations. Drugs Today (Barc) 2008 Oct;44(10):751-5
2-N-(6'-(1''-pyridinium)hexanoyl)sphingosine  0   *Ceramides *Pyridinium Compounds. Br J Cancer 2009 Feb 24;100(4):626-32
iotrochotamide II  0   *Ceramides. Nat Prod Res 2009;23(1):86-92
iotrochotamide I  0   *Ceramides. Nat Prod Res 2009;23(1):86-92
K112PC-5 compound  0   *Ceramides. Arch Pharm Res 2008 Aug;31(8):1004-9
Bio 391  0   *Ceramides. J Dermatol Sci 2008 Jul;51(1):37-43
PC 104  0   *Ceramides. J Dermatol Sci 2008 Jul;51(1):37-43
XM 462  0   *Ceramides *Sulfides. ChemMedChem 2008 Jun;3(6):946-53
N-(5-dodecyl-4-hydroxytetrahydrofuran-3-yl)-2-hydroxyheptadecanamide  0   *Ceramides *Furans. Chem Biodivers 2008 Jan;5(1):120-5
D-erythro-2-N-(160-(1''-pyridinium)hexadecanoyl)sphingosine bromide  0   *Ceramides Sphingosine/*analogs & derivatives. Br J Cancer 2008 Jan 15;98(1):98-105
N-tetracosanoyl-(L)-serine tetradecyl ester  0   *Ceramides Serine/*analogs & derivatives. Br J Dermatol 2007 Oct;157(4):704-12
N-(4',5'-dithiaheptanoyl)-D-erythro-ceramide  0   *Ceramides. Cancer Lett 2007 Jun 18;251(1):53-8
trametenamide A  0   *Ceramides. J Med Chem 2006 Sep 21;49(19):
trametenamide B  0   *Ceramides. J Med Chem 2006 Sep 21;49(19):5830-9
asteriaceramide A  0   *Ceramides Sphingosine/*analogs & derivatives. J Nat Prod 2006 Jul;69(7):1080-2
beta-galactosyl ceramide  0   *Ceramides *Monosaccharides. J Org Chem. 2005 Sep 30;70(20):8228-30
C4-methylene D-erythro-N-octanoylceramide  0   *Ceramides. Org Lett 2005 Apr 14;7(8):1645-8
damicoside  0   *Ceramides *Disaccharides. J Med Chem 2005 Nov 17;48(23):7411-7
N-(alpha-hydroxyoctadecanoyl)phytosphingosine  0   *Ceramides. Chem Phys Lipids 2005 Jan;133(1):89-102
(2S,3R,4E,8E)-N-hexadecanoyl-2-amino-4,8-octadecadiene-1,3-diol  0   *Alkadienes *Ceramides. Arch Pharm Res. 2005 Mar;28(3):290-3
1-O-beta-D-glucopyranosyl-(2S,3S,4R,8E)-2-((2R)-2-hydroxytetracosanoylamino)-1,3,4-octodecanetriol-8-ene  0   *Ceramides. Lipids 2004 Sep;39(9):907-13
9-O-MGN-MGN-MGN-IPCA  0   *Ceramides. Chem Pharm Bull (Tokyo). 2004 Sep;52(9):1140-2
N-hexanoyldihydrosphingosine  0   *Ceramides. Arterioscler Thromb Vasc Biol 2004 May;24(5):943-8
2-octanoylamido-4,6-octadecadiene-1,3-diol  0   *Ceramides. J Pharmacol Exp Ther 2004 May;309(2):523-32
hemisceramide  0   *Ceramides. Yao Xue Xue Bao 2002 Jun;37(6):440-3
N-lactyldihydrosphingosine  0   *Ceramides. J Med Chem 2003 Jul 31;46(16):3445-7
N-lactylsphingosine  0   *Ceramides. J Med Chem 2003 Jul 31;46(16):3445-7
2-(2'-hydroxy-21'-methyldocosanoylamino)-1,3,4-pentadecanetriol  0   *Ceramides Sex Attractants. Biosci Biotechnol Biochem 2002 Jul;66(7):1531-7
N-stearoylsphinganine  0   *Ceramides. J Biol Chem 2002 Sep 20;277(38):35642-9
2-N-(10-pyrenedecanoyl)-1,3,17-trihydroxy-17-(3,5-dinitrobenzoyl)-4-heptadecene  0   *Ceramides. Chem Phys Lipids 2002 Feb;114(2):181-91
armillaramide  0   *Ceramides Fatty Acids. Fitoterapia 2001 Dec;72(8):858-64
lactariamide B  0   *Ceramides. J Nat Prod 2001 Sep;64(9):1246-8
lactariamide A  0   *Ceramides. J Nat Prod 2001 Sep;64(9):1246-8
TriCeram  0   *Ceramides. Arch Dermatol 2001 Aug;137(8):1110-2
1,3-dihydroxy-2-((hexadecanoyl)amino)nonadeca-4-ene  0   *Ceramides. J Asian Nat Prod Res 2001;3(1):23-9
2-(2'-hydroxytetracosanoylamino)octadecane-1,3,4-triol  0   *Ceramides. Lipids 2001 Feb;36(2):175-80
EGL-II glycosphingolipid  0   *Ceramides Fatty Acids. J Biochem (Tokyo) 2001 Jan;129(1):93-100
4,5-epoxy-N-acetylsphingosine  0   *Ceramides. Z Naturforsch (C) 2000 Nov-Dec;55(11-12):981-6
2-octadecanoylamino-1,3-dihydroxy-octadecene-4  0   *Ceramides. Biophys J 2000 Nov;79(5):2616-23
N-(4,4-difluoro-5,7-dimethyl-4--bora-3a,4a-diaza-s-indacene-3-pentanoyl)sphingosine  0   *Boron Compounds *Ceramides. Biochem J 2000 Feb 1;345 Pt 3:603-10
2-(hexanoylamino)-5-phenylpent-4-ene-1,3-diol  0   *Ceramides. J Med Chem 1999 Jul 15;42(14):2697-705
2-acetamido-4-dodecene-1,3-diol  0   *Ceramides. J Med Chem 1999 Jul 15;42(14):2697-705
C12-NBD-ceramide  0   *Ceramides 4-Chloro-7-nitrobenzofurazan. J Biochem (Tokyo) 1999 Apr 1;125(4):746-9
AGL 533  0   *Ceramides. Bioorg Med Chem Lett 1999 Mar 8;9(5):697-702
AGL 529  0   *Ceramides. Bioorg Med Chem Lett 1999 Mar 8;9(5):697-702
AGL 563  0   *Ceramides. Bioorg Med Chem 1998 Oct;6(10):1905-10
omega-amino-ceramide  0   *Ceramides. Anal Biochem 1998 Oct 15;263(2):183-8
N-docosanoyl-16-methylheptadecasphing-4-enine  0   *Ceramides. J Nat Prod 1998 Jun 26;61(6):823-6
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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