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Chelating Agents

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Definition: Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.  coordinate with specific chelating agent + metal being chelated   
See Also Antidotes; Iron Chelating Agents
Examples Iron Chelating Agents
Other names Complexons; Metal Antagonists; Antagonists, Metal; Agents, Chelating; Chelators
Substances having this pharmacologic action: chelex; sodium thiosulfate; (ethylenedinitrilo)-tetramethylenephosphonic acid; tetrathiomolybdate; pyridoxal isonicotinoyl hydrazone; 1,10-phenanthroline; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid; EDDA; triethylenetetraminehexaacetic acid; N-(hydroxyethyl)ethylenediaminetriacetic acid; cobalt-ethylenediamine tetraacetic acid chelate; bathocuproine sulfonate; Quin2-acetoxymethyl ester; N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid; dihydroxyethyldithiocarbamate; 5,5'-difluoro-1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid; iminodiacetic acid; dipicolinic acid; CDTA; Chitosan; neocuproine; Phytochelatins; alanosine; Fura-2; Technetium Tc 99m Pentetate; Ditiocarb; Razoxane; Thenoyltrifluoroacetone; Nitrilotriacetic Acid; Unithiol; 2,2'-Dipyridyl; Trientine; Citric Acid; Penicillamine; Dimercaprol; Succimer; Dithizone; Cuprizone; Pentetic Acid; Edetic Acid; Egtazic Acid; Humic Substances; Caseins; disalicylaldehyde ethylenediamine; benphothiamine; bathophenanthroline disulfonic acid; calcium acetate; sevelamer; zinquin; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester; 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid; Indo-1 pentaacetoxymethyl ester; diazo-2; theaflavin; 1-(2-nitro-4,5-dimethoxyphenyl)-N,N,N',N'-tetrakis((oxycarbonyl)methyl)-1,2-ethanediamine; 5,5'-dimethyl-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetate; acteoside; N-benzylglucamine dithiocarbamate; indo-1; gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate; nitr 5; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
triazacyclononane-phosphinic acid  0   *Aza Compounds *Phosphinic Acids Chelating Agents. Chemistry. 2011 Dec 23;17(52):14718-22
cysteinyl-phenyl-triaminohexaacetate  0   *Acetic Acids Cysteine/*analogs & derivatives Chelating Agents. J Biomol NMR. 2011 Nov;51(3):329-37.
ethylenediaminetetraacetic acid bis-(ethyl phenylalaninate)  0   Edetic Acid/*analogs & derivatives Chelating Agents. Bioorg Med Chem Lett 2001 Oct 8;11(19):2573-5
Phen Green SK  0   Organic Chemicals Chelating Agents Fluorescent Dyes. Toxicol Appl Pharmacol 2001 Jul 1;174(1):27-34
(1,4,7-trimethyl-1,4,7-triazacyclononane)iron(III)  0   *Ferric Compounds Chelating Agents. Nucleic Acids Res 1998 May1;26(9):2086-91
1,4,7-triazacyclononane  4730-54-5 1H-1,4,7-Triazonine, octahydro  *Heterocyclic Compounds Chelating Agents. Int J Rad Appl Instrum (B) 1992 Apr;19(3):269-74
Trialon B  128523-75-1   Organic Chemicals Chelating Agents. Zh Mikrobiol Epidemiol Immunobiol 1989;8:5
Benz2  0   Organic Chemicals Calcium Chelating Agents. Biochim Biophys Acta 1984;773(1):143
Chelex 100  11139-85-8   *Resins, Synthetic Cation Exchange Resins Chelating Agents. Biochem Biophys Res Commun 1980;93(2):558

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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