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Chemotactic Factors

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Definition: Chemical substances that attract or repel cells. The concept denotes especially those factors released as a result of tissue injury, microbial invasion, or immunologic activity, that attract LEUKOCYTES; MACROPHAGES; or other cells to the site of infection or insult.  /biosyn /physiol permitted   
See Also Pheromones
Examples Chemokines; Chemotactic Factors, Eosinophil; Leukocyte Migration-Inhibitory Factors; N-Formylmethionine Leucyl-Phenylalanine 		Other names Cytotaxins; Cytotaxinogens; Chemotaxins; Macrophage Chemotactic Factors; Chemotactic Factors, Macrophage; Chemoattractants
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
chemerin protein, mouse  0   *Chemotactic Factors *Intercellular Signaling Peptides and Proteins. J Biol Chem 2007 Sep 21;282(38):28175-88
F2L protein, mouse  0   *Chemotactic Factors. J Immunol 2007 Feb 1;178(3):1450-6
F2L peptide, human  0   *Chemotactic Factors *Peptides. J Exp Med. 2005 Jan 3;201(1):83-93
V1ra1 protein, mouse  0   *Chemotactic Factors Receptors, Odorant Vomeronasal Organ.
S100A2 protein, rat  0   *Chemotactic Factors *S100 Proteins. Cell Mol Biol (Noisy-le-grand) 2003 Jun;49(4):485-6
bourgeonal  18127-01-0   *Aldehydes Chemotactic Factors. Science 2003 Mar 28;299(5615):2054-8
VN1R1 protein, human  0   *Chemotactic Factors Receptors, Odorant Vomeronasal Organ. Nat Genet 2000 Sep;26(1):18-9
Trp-Lys-Tyr-Met-Val-Met  0   *Oligopeptides Chemotactic Factors Stereoisomerism. Clin Biochem 1998 Apr;31(3):137-41
S100A2 protein, human  0   *Chemotactic Factors *S100 Proteins. J Cell Biol 1989 Feb;108(2):569-78
smooth muscle cell-derived migration factor  0   *Chemotactic Factors *Muscle Proteins. Ann N Y Acad Sci 1995 Jan 17;748:575-7
cheV protein, bacteria  0   *Bacterial Proteins *Chemotactic Factors. J Bacteriol 1994 May;176(9):2727-35
hematopoietic stem cell-chemotactic factor  0   *Chemotactic Factors *Stem Cell Factor Hematopoietic Stem Cells. Blood 1994 Feb 15;83(4):964-71
formyl-norleucyl-leucyl-phenylalanyl-norleucyl-tyrosyl-lysine-DTPA  0   *Chemotactic Factors Pentetic Acid/*analogs & derivatives. J Nucl Med 1993 Dec;34(12):2130-4
neutrophil chemotactic factor, Dirofilaria immitis  0   *Chemotactic Factors Dirofilaria immitis. Mol Immunol 1993 Oct;30(14):1315-20
5-oxo-6,8,11,14-eicosatetraenoic acid  126432-17-5   *Arachidonic Acids Chemotactic Factors Eosinophils. Biochem Biophys Res Commun 1993 Apr 15;192(1):129-34
CheB protein, Bacteria  139076-03-2   *Bacterial Proteins Chemotactic Factors. J Biol Chem 1991;266(19):12301
alveolar macrophage-chemotactic factor-II  0   *Chemotactic Factors. J Biol Chem 1991;266(13):8455
platelet-derived neutrophil chemotactic peptide  0   *Chemotactic Factors. Biochem Biophys Res Commun 1990;172(2):898
CCL1 protein, human  0   *Chemokine CCL1 Chemotactic Factors. J Immunol 1990;145(8):2737
Icaria chemotactic peptide, Lys(7)  108567-69-7   *Chemotactic Factors. Biochem Biophys Res Commun 1990;168(2):596
Icaria chemotactic peptide  97055-09-9   *Chemotactic Factors Wasp Venoms. Biochem Biophys Res Commun 1990;168(2):596
glioma-derived monocyte chemotactic factor 2  0   *Chemotactic Factors. Proc Natl Acad Sci USA 1989;86(6):1850
macrophage migration enhancement factor  0   *Chemotactic Factors. Cell Immunol 1985;95(1):137
N-formylmethionyl-leucyl-phenylalanyl-lysine  81213-55-0   N-Formylmethionine Leucyl-Phenylalanine/*analogs & derivatives Chemotactic Factors. Clin Nephrol 1986;26(1):37
5-hydroxy-6,8,11,14-eicosatetraenoic acid  72255-35-7 6,8,11,14-eicosatetraenoic acid, 5-hydroxy  *Hydroxyeicosatetraenoic Acids Chemotactic Factors. J Clin Invest 64(5):1457;1979
F-chemotactic peptide  71901-21-8 L-Lysine, N(2)-(N-(N-(N-(N-(N-formyl-L-norleucyl)-L-leucyl)-L-phenylalanyl)-L-norleucyl)-L-tyrosyl)  *Oligopeptides Chemotactic Factors Chemotaxis, Leukocyte Neutrophils. J Biol Chem 254(21):10700;1979; Proc Natl Acad Sci USA 1980;77(2):1000
N-formylmethionylphenylalanine  22008-60-2   *Dipeptides Chemotactic Factors. Biochem Biophys Res Commun 1979;90(2):481; Clin Exp Immunol 1979;38(2):294; FEBS Lett 1979;108(1):47; Infect Immun 1979;26(3):996; J Clin Invest 1980;65(4):804; J Immunol 121(1):172;1978; J Immunol Methods 25(4):337;1979; Langenbecks Arch Chir 1979; suppl:261
cocytotaxin  0   *Chemotactic Factors. Antibiotics Chemother 19:443;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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