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Chemotactic Factors, Eosinophil

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Definition: Cytotaxins liberated from normal or invading cells that specifically attract eosinophils; they may be complement fragments, lymphokines, neutrophil products, histamine or other; the best known is the tetrapeptide ECF-A, released mainly by mast cells.  chemotactic substances attracting eosinophils, not liberated by eosinophils; /biosyn /physiol permitted; DF: ECF A   
Examples N-Formylmethionine Leucyl-Phenylalanine 		Other names Eosinophil Chemotaxins; Eosinophil Chemotactic Factors; Factors, Eosinophil Chemotactic; Chemotaxins, Eosinophil
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
eosinophil chemotactic factor-L, mouse  0   *Chemotactic Factors, Eosinophil *Chemokines Osteoclasts. J Bone Miner Res 2003 Jul;18(7):1332-41
5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid  142828-12-4   *Hydroxyeicosatetraenoic Acids Chemotactic Factors, Eosinophil. J Biol Chem 1992 Jun 25;267(18):12482-8
alanyl-glycyl-seryl-glutamic acid  61756-28-3 L-Glutamic acid, N-(N-(N-L-alanylglycyl)-L-seryl)  *Chemotactic Factors, Eosinophil *Oligopeptides. Gastroenterology 1990;98(4):929
chemotactin  65405-98-3 Chemotactin  *Chemotactic Factors, Eosinophil Complement C5. Chest 75(2):259;1979
lymphotactin  0   *Lymphokines *Sialoglycoproteins Chemotactic Factors, Eosinophil Interleukins Lymphocytes. Inflammation 2(2):104;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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