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Chenodeoxycholic Acid

More information in Books or onNLM PubMed
Definition: A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.  a bile acid; /biosyn /physiol permitted   
Pharmacological Action Cathartics; Gastrointestinal Agents
Examples Glycochenodeoxycholic Acid; Taurochenodeoxycholic Acid
Other names Gallodesoxycholic Acid; Chenodiol; Chenodeoxycholate; Chenic Acid; Chenodeoxycholate, Sodium; Acid, Gallodesoxycholic; Acid, Chenodeoxycholic; Acid, Chenique; Zambon Brand of Chenodeoxycholic Acid; Tramedico Brand of Chenodeoxycholic Acid; Solvay Brand of Chenodeoxycholic Acid; Sodium Chenodeoxycholate; Acid, Chenic; Quenocol; Quenobilan; Henohol; Falk Brand of Chenodeoxycholic Acid; Estedi Brand of Chenodeoxycholic Acid; Chenophalk; ChenofalkDrugs* : CHENIX; CHENODIOL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
methyl-3beta-hydroxy-5alpha,6alpha-epoxycholanate  0   Chenodeoxycholic Acid/*analogs & derivatives. Pharmacology. 2010;86(5-6):306-12
sodium 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate  0   Chenodeoxycholic Acid/*analogs & derivatives. Methods Find Exp Clin Pharmacol 2008 Mar;30(2):107-13
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate  0   Chenodeoxycholic Acid/*analogs & derivatives. Eur J Drug Metab Pharmacokinet 2007 Jan-Mar;32(1):7-12
deoxycholyl-L-lysyl-methylester  0   Chenodeoxycholic Acid/*analogs & derivatives Lysine/*analogs & derivatives. Diabetologia 2005 Mar;48(3):405-11
HS-1199  0   Chenodeoxycholic Acid/*analogs & derivatives. Int J Oncol. 2005 Sep;27(3):653-9
avicholic acid  0   Chenodeoxycholic Acid/*analogs & derivatives. Org Lett 2004 Jan 8;6(1):31-4
HS 1200  0   Chenodeoxycholic Acid/*analogs & derivatives. Cancer Lett 2001 Feb 10;163(1):83-93
16-hydroxychenodeoxycholic acid  0   Chenodeoxycholic Acid/*analogs & derivatives. J Lipid Res 2002 May;43(5):685-90
6-ethylchenodeoxycholic acid  0   Chenodeoxycholic Acid/*analogs & derivatives. J Med Chem 2002 Aug 15;45(17):3569-72
chenodeoxycholyl-2-(4-N-nitrobenzoxadiazolyl)aminobutyl-glycine  0   Chenodeoxycholic Acid/*analogs & derivatives Glycine/*analogs & derivatives. Am J Physiol 1997 Jun;272(6 Pt 1):G1416-24
3-glucosido-chenodeoxycholic acid  139026-50-9   *Glucosides Chenodeoxycholic Acid/*analogs & derivatives. J Biol Chem 1997 Apr 25;272(17):11261-7
23-hydroxychenodeoxycholic acid  0   Chenodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1996 Jan;37(1):98-112
chenodeoxycholyl-nitrobenzoxadiazolyl-lysine  0   Chenodeoxycholic Acid/*analogs & derivatives Lysine/*analogs & derivatives. Hepatology 1995 Aug;22(2):637-47
3,7-dihydroxy-25,26-bishomocholane-26-sulfonate  0   Chenodeoxycholic Acid/*analogs & derivatives. Lipids 1995 Jan;30(1):71-8
1-hydroxychenodeoxycholic acid  0   Chenodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1994 Nov;35(11):2041-8
homochenodeoxycholic acid  38636-78-1 Cholane-24-carboxylic acid, 3,7-dihydroxy-, (3alpha,5beta,7alpha)  Chenodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1993 Jun;34(6):915-21
24-norchenodeoxycholic acid  86386-61-0 24-Norcholan-23-oic acid, 3,7-dihydroxy-, (3alpha,5beta,7alpha)  Chenodeoxycholic Acid/*analogs & derivatives. J Biol Chem 1993 May 25;268(15):11239-46
3,7-dihydroxy-24-norcholane-23-sulfonate  145523-79-1   Chenodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1992 Nov;33(11):1629-37
3,7-dihydroxy-25-homocholane-25-sulfonate  145523-80-4   Chenodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1992 Nov;33(11):1629-37
chenodeoxycholyllysylrhodamine  0   *Rhodamines Chenodeoxycholic Acid/*analogs & derivatives. Biochim Biophys Acta 1992 Jun 5:1126(1):35-40
3,7-dihydroxycholane-24-sulfonate  130593-74-7   Chenodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1990;31(7):1323
N-chenodeoxycholyl-2-fluoro-beta-alanine  114818-27-8   Chenodeoxycholic Acid/*analogs & derivatives beta-Alanine/*analogs & derivatives. Drug Metab Dispos 1988;16(6):892
chenodeoxycholyltyrosine  103528-65-0   Chenodeoxycholic Acid/*analogs & derivatives. Biochim Biophys Acta 1987;926(2):154
23-norchenodeoxycholic acid  0   Chenodeoxycholic Acid/*analogs & derivatives. Am J Physiol 1987;252(2 Pt 1):G219
sarcochenodeoxycholic acid  88446-86-0   Chenodeoxycholic Acid/*analogs & derivatives. Yakugaku Zasshi 1984;104(5):466
N-(2-aminoethyl)-3,7-dihydroxycholan-24-amide  78793-10-9 Cholan-24-amide, N-(2-aminoethyl)-3,7-dihydroxy-, (3alpha,5beta,7alpha)  Chenodeoxycholic Acid/*analogs & derivatives. Steroids 1981;37(4):393
chenodeoxycholate sulfate conjugate  39280-88-1   Chenodeoxycholic Acid/*analogs & derivatives. J Biol Chem 1980;255(21):10157
3,7-dihydroxy-12-oxocholanoic acid  2458-08-4 cholan-24-oic acid, 3,7-dihydroxy-12-oxo-, (3 alpha,5 beta,7 alpha)  Chenodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1980;21(4):477
methyl 3,7-dihydroxychol-4-en-24-oate  66471-09-8 Chol-4-en-24-oic acid, 3,7-dihydroxy-, methyl ester, (3alpha,7alpha)  Chenodeoxycholic Acid/*analogs & derivatives. Steroids 32(1):85;1978
methyl 3,7-dihydroxycholanate  51446-77-6 Cholan-24-oic acid, 3,7-dihydroxy-, methyl ester, (3beta,5alpha,7beta)  Chenodeoxycholic Acid/*analogs & derivatives. Steroids 23(2):221;1974
3-oxo-7-hydroxychol-4-enoic acid  14772-95-3 (7 alpha)-7-hydroxy-3-oxochol-4-en-24-oic acid  Chenodeoxycholic Acid/*analogs & derivatives. J Biochem (Tokyo) 71(4):579;1972
3,7-dihydroxychol-5-enoic acid  19246-13-0   Chenodeoxycholic Acid/*analogs & derivatives. J Biochem (Tokyo) 82(4):1093;1977; J Biochem (Tokyo) 83(3):799;1978; J Biochem 72(3):529;1972; Steroids 32(1):73;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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