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Cholecystokinin

More information in Books or onNLM PubMed
Definition: A peptide, of about 33 amino acids, secreted by the upper INTESTINAL MUCOSA and also found in the central nervous system. It causes gallbladder contraction, release of pancreatic exocrine (or digestive) enzymes, and affects other gastrointestinal functions. Cholecystokinin may be the mediator of satiety.     
Pharmacological Action Cholagogues and Choleretics
See Also Gastrointestinal Agents; Receptors, Cholecystokinin
Examples Sincalide 		Other names Pancreozymin; Uropancreozymin; Cholecystokinin 33; CCK-33
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cholecystokinin (26-32) phenylethyl ester, tyrosyl-glycyl-(norleucyl(28.31)-tryptophyl(30))  0   *Peptide Fragments Cholecystokinin/*analogs & derivatives Ligands. Am J Physiol Cell Physiol. 2012 Feb;302(3):C615-27.
cholecystokinin (29-33)-amide  0   *Cholecystokinin *Peptide Fragments. Biochem J 2002 Sep 1;366(Pt 2):521-9
sulfated cholecystokinin 15  0   *Cholecystokinin *Peptide Fragments. Biochem Biophys Res Commun 2002 May 10;293(3):1053-9
CCK 15  0   *Cholecystokinin *Peptide Fragments. J Med Chem 2002 Feb 14;45(4):762-9
cholecystokinin 12 C-terminal fragment  0   *Cholecystokinin *Peptide Fragments. Peptides 2001 Aug;22(8):1271-7
2,7-dioxo-2,3,4,5,6,7-hexahydro-1H-benzo(h)(1,4)diazonine  0   *Quinones Cholecystokinin/antagonists & inhibitors. J Med Chem 2000 Sep 21;43(19):3518-29
cholecystokinin 8  0   *Cholecystokinin *Peptide Fragments. Biochem Biophys Res Commun 2000 Jun 24;273(1):188-91
cholecystokinin (26-33), indium-DOTA(0)-Asp(26)-Nle(28,31)  0   *Cholecystokinin *Peptide Fragments. J Nucl Med 1999 Dec;40(12):2081-7
cholecystokinin (26-33), iodo-Tyr-Gly--Nle(28,31)-Bpa(33)  0   *Peptide Fragments Cholecystokinin/*analogs & derivatives Iodine Radioisotopes Ligands Receptors, Cholecystokinin/agonists. J Med Chem 1999 Jun 17;42(12):2105-11
cholecystokinin (26-33), iodo-Tyr-Gly-Nle(28,31)-Bpa(29-33)  0   *Peptide Fragments Cholecystokinin/*analogs & derivatives Iodine Radioisotopes Ligands Receptors, Cholecystokinin/agonists. J Med Chem 1999 Jun 17;42(12):2105-11
MP 2286  0   Cholecystokinin/*analogs & derivatives Pentetic Acid/*analogs & derivatives Ligands. Eur J Nucl Med 1998 May;25(5):481-90
MP 2288  0   Cholecystokinin/*analogs & derivatives Pentetic Acid/*analogs & derivatives Ligands. Eur J Nucl Med 1998 May;25(5):481-90
benzyloxycarbonyl-glycyl-tryptophyl-methionyl-aspartyl(OBu-t)-phenylalaninamide  0   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Biotechnol Prog 1997 Nov-Dec;13(6):783-7
RB 360  0   *Oligopeptides Cholecystokinin/agonists Receptors, Cholecystokinin/agonists Stereoisomerism. J Med Chem 1997 Feb 28;40(5):647-58
ARL 15849XX  0   Cholecystokinin/*analogs & derivatives. J Pharm Biomed Anal 1996 Mar;14(5):593-600
4-(biotin-epsilon-(aminohexanoyl)oxymethyl)-3-nitrobenzoyl-glycyl-(propionyl)ornithinyl-epsilon-aminohexanoyl-cholecystokinin  157203-06-0   Cholecystokinin/*analogs & derivatives. Anal Biochem 1994 May 1;218(2):330-7
4-alanyloxymethyl-3-nitrobenzoyl-epsilon-aminohexanoyl-cholecystokinin  157203-07-1   Cholecystokinin/*analogs & derivatives. Anal Biochem 1994 May 1;218(2):330-7
SNF 9007  156161-88-5   *Peptide Fragments Cholecystokinin/*analogs & derivatives. J Pharmacol Exp Ther 1994 Feb;268(2):1003-9
BC 264  0   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Synapse 1990;6(1):73-80
dimyristoylmercaptoglycero-N(alpha)maleoyl-beta-alanyl(Thr,Nle)-CCK-9  151705-73-6   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Biochim Biophys Acta 1993 Sep 19;1151(2):111-9
t-butyloxycarbonyl-sulfotyrosyl-norleucyl-glycyl-tyrosyl-aspartyl-2-phenylethyl ester  156586-96-8   Cholecystokinin/*analogs & derivatives. J Biol Chem 1993 Sep 15;268(26):19769-75
SNF 8815  154336-13-7   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Cancer Res 1993 Sep 1;53(17):3925-9
cholecystokinin-J  144396-38-3   *Peptide Fragments Cholecystokinin/*analogs & derivatives. J Biol Chem 1992 Dec 5;267(34):24387-93
A 68552  112882-74-3   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Pharmacol Biochem Behav 1992 Oct;43(2):369-76
Ro 23-7014  113714-78-6   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Pept Res 1991 Mar-Apr;4(2):59-65
cholecystokinin (31-39), Thr(34)-Ahx(37)  124869-86-9   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Eur J Biochem 1992 Feb 15;204(1):273-9
desulfated benzyloxycarbonyl cholecystokinin (26-33)  25687-34-7   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Biochem Biophys Res Commun 1991;181(3):989
cholecystokinin (25-33), biotinyl-Tyr-Gly-(Thr(28)-Nle(31))  0   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Biochim Biophys Acta 1991;1080(2):181
JMV 176  119068-32-5 L-Phenylalaninamide, N-(5-((2-(((1,1-dimethylethoxy)carbonyl)amino)-1-oxo-3-(4-(sulfooxy)phenyl)propyl)amino)-1,4-dioxononyl)-L-tryptophyl-L-norleucyl-L-alpha-aspartyl-, (S-(R*,R*))  Cholecystokinin/*analogs & derivatives. Neuropeptides 1990;17(4):187
cholecystokinin (25-33), Tyr(25)-Nle(28,31)  132032-04-3   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Eur J Pharmacol 1990;191(1):107
pBC 264  125236-85-3   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Eur J Pharmacol 1989;168(2):269
cholecystokinin (25-33),2-(4-azidosalicylamido)-1,3-dithiopropionate(Thr(28)-AHX(31))  124894-89-9   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Eur J Biochem 1989;185(2):397
cholecystokinin, Gly  124762-72-7   *Cholecystokinin *Protein Precursors. Gastroenterology 1989;97(5):1159
butyloxycarbonyl-tryptophyl-leucyl-aspartyl-phenylalaninamide  17554-05-1   Cholecystokinin/*analogs & derivatives Tetragastrin/*analogs & derivatives. Drug Des Deliv 1987;2(1):49
U 67827E  103494-23-1   Cholecystokinin/*analogs & derivatives. Appetite 1989;12(2):145
V-9-M cholecystokinin nonapeptide  99291-20-0   *Cholecystokinin *Peptide Fragments. Can J Physiol Pharmacol 1989;67(3):223
procholecystokinin  78206-77-6   *Cholecystokinin *Protein Precursors. Can J Physiol Pharmacol 1989;67(3):223
BC 197  115295-08-4 L-Phenylalaninamide, N- ((1,1-dimethylethoxy)carbonyl)-D-alpha-aspartyl-O-sulfo-L-tyrosyl-L-norleucyl-D-lysyl-L-tryptophyl-L-norleucyl-L-alpha-aspartyl-, cyclic (1-4)-peptide  *Peptide Fragments Cholecystokinin/*analogs & derivatives. Neuropeptides 1989;13(2):89
cholecystokinin (31-33) amide, butyloxycarbonyl  5920-14-9   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Life Sci 1989;44(2):533
cholecystokinin (27-32) amide, benzoyloxycarbonyl  92773-91-6   *Peptide Fragments Cholecystokinin/*analogs & derivatives. Life Sci 1989;44(2):533
cholecystokinin (1-14)  80980-82-1   *Cholecystokinin *Peptide Fragments. Life Sci 1987;41(16):1915
cholecystokinin 9  108050-84-6   *Cholecystokinin *Peptide Fragments. J Med Chem 1987;30(8):1366
cholecystokinin precursor C-terminal pentapeptide  114942-10-8   *Cholecystokinin *Peptide Fragments. Peptides 1987;8(1):95
cholecystokinin 10 C-terminal fragment  25842-57-3   *Cholecystokinin *Peptide Fragments. Regul Pept 1986;15(3):205
cholecystokinin 33 (10-20)  122998-75-8   *Cholecystokinin *Peptide Fragments. Cell Tissue Res 1986;244(3):519
cholecystokinin (10-20)  100900-23-0   *Cholecystokinin *Peptide Fragments. Acta Pharmacol Toxicol (Copenh) 1986;58(2):115
cholecystokinin 21  101831-07-6   *Peptide Fragments *Cholecystokinin. Acta Pharmacol Toxicol (Copenh) 1986;58(2):115
cholecystokinin C-terminal flanking peptide  101162-62-3   *Cholecystokinin *Peptide Fragments. FEBS Lett 1986;196(1):5
cholecystokinin 22 C-terminal fragment  95690-77-0   *Cholecystokinin *Peptide Fragments. Peptides (Fayetteville) 1984;5(6):1203
cholecystokinin (25-33), Thr(28)-Nle(31)  77568-41-3 Caerulein, 1-de(5-oxo-L-proline)-2-L-arginine-8-L-norleucine-, (R)  *Peptide Fragments Cholecystokinin/*analogs & derivatives. Regul Pept 1984;8(4):291
preprocholecystokinin  89624-02-2   *Cholecystokinin *Protein Precursors. Proc Natl Acad Sci USA 1984;81(14):4307
cholecystokinin 58  83381-92-4   *Cholecystokinin. Am J Physiol 1983;45(2):G313
cholecystokinin (27-32)-amide  86367-90-0 L-alpha-Asparagine, N2-(N-(N-(N-(N-(O-sulfo-L-tyrosyl)-L-methionyl)glycyl)-L-tryptophyl)-L-methionyl)  *Peptide Fragments Cholecystokinin/*analogs & derivatives. J Biol Chem 1983;258(11):6746
cholecystokinin 5-pentagastrin  0   Cholecystokinin/*analogs & derivatives Pentagastrin/*analogs & derivatives. Eur J Pharmacol 1983;87(1):173
cholecystokinin 39  79955-77-4 Cholecystokinin-39  Cholecystokinin/*analogs & derivatives. Acta Diabetol Lat 1981;18(4):345

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