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Choline O-Acetyltransferase

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Definition: An enzyme that catalyzes the formation of acetylcholine from acetyl-CoA and choline. EC 2.3.1.6.      Other names Choline Acetyltransferase; Choline Acetylase; O-Acetyltransferase, Choline; Choline O Acetyltransferase; Acetyltransferase, Choline; Acetylase, Choline
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bicycloillicinone asarone acetal  0   *Bicyclo Compounds *Dioxoles Choline O-Acetyltransferase/agonists. Planta Med 1997 Jun;63(3):274-5
garsubellin A  0   *Terpenes Choline O-Acetyltransferase/agonists. Chem Pharm Bull (Tokyo) 1997 May;45(5):947-9
CAT development factor  0   *Nerve Growth Factors Choline O-Acetyltransferase. J Neurosci 1992;12(1):171
1-(2-benzoylethyl)pyridinium  70013-89-7   *Pyridinium Compounds Choline O-Acetyltransferase/antagonists & inhibitors. Brain Res Bull 1991;26(6):845
1-methyl-4-(1-naphthylvinyl)-1,2,3,6-tetrahydropyridine hydrochloride  113009-52-2 Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-(2-(1-naphthalenyl)ethenyl)-, hydrochloride, (E)  Naphthylvinylpyridine/*analogs & derivatives Choline O-Acetyltransferase/antagonists & inhibitors. Toxicol Appl Pharmacol 1991;107(2):336
2-naphthoylethyltrimethylammonium  31059-54-8   *Quaternary Ammonium Compounds *Naphthalenes Choline O-Acetyltransferase/antagonists & inhibitors. J Pharmacol Exp Ther 1988;245(1):72
BW 813U  100098-85-9   *Oxazines Choline O-Acetyltransferase/antagonists & inhibitors. Pharmacol Biochem Behav 1986;25(3):521
1,2-dihydro-2-imino-4-(1-naphthylvinyl)-1-pyridineethanol  30841-78-2   *Dihydropyridines Choline O-Acetyltransferase/antagonists & inhibitors. Histochemistry 1983:78(3):339
N,N-dimethylepinephrine  38522-73-5   Epinephrine/*analogs & derivatives Choline O-Acetyltransferase/antagonists & inhibitors. Proc Natl Acad Sci USA 1983;80(8):2107
3-trimethylaminomethylcatechol  84304-14-3 Benzenemethanaminium, 2,3-dihydroxy-N,N,N-trimethyl  *Catechols Choline O-Acetyltransferase/antagonists & inhibitors. Biochem Biophys Res Commun 1982;107(4):1265
Rheumajecta  0   *Catalase *Choline O-Acetyltransferase *Sulfate Adenylyltransferase *Sulfurtransferases Drug Combinations. Rheumatol Rehabil 1980;19(1):60
(2-benzoylethyl)trimethylammonium  24472-88-6   Acetylcholine/*analogs & derivatives Choline O-Acetyltransferase/antagonists & inhibitors. J Pharmacolog Exptl Therap 205(3):624;1978
N-(2-hydroxyethyl)-4-(beta-(1-naphthylvinyl)pyridinium bromide)  26468-01-9   Naphthylvinylpyridine/*analogs & derivatives Choline O-Acetyltransferase/antagonists & inhibitors. Acta Pharmacol Toxicol 43(4):280;1978; J Neurochem 22(4):611;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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