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Circadian Rhythm

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Definition: The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs and stimuli, hormone secretion, sleeping, and feeding.  drug administration based on circadian rhythm   
See Also Biological Clocks; Chronotherapy; Circadian Clocks; Photoperiod
Examples Activity Cycles 		Other names Twenty-Four Hour Rhythm; Nyctohemeral Rhythm; Diurnal Rhythm; Twenty-Four Hour Rhythms; Twenty Four Hour Rhythm; Rhythms, Twenty-Four Hour; Rhythms, Nyctohemeral; Rhythms, Diurnal; Rhythms, Circadian; Rhythm, Twenty-Four Hour; Rhythm, Nyctohemeral; Rhythm, Diurnal; Rhythm, Circadian; Nyctohemeral Rhythms; Diurnal Rhythms; Circadian Rhythms
 
SubstanceCAS Registry & nameCategoriesSource
longdaysin  0   Adenine/*analogs & derivatives Circadian Rhythm. PLoS Biol 2010;8(12):e1000559
timeless2 protein, Drosophila  0   *Drosophila Proteins Biological Clocks Circadian Rhythm. Curr Biol. 2010 Feb 23;20(4):346-52
curled protein, Drosophila  0   *Drosophila Proteins Circadian Rhythm. Genetics 2009 Sep;183(1):219-32
clock1 protein, zebrafish  0   *DNA-Binding Proteins Circadian Rhythm. J Neurogenet 2008 Apr-Jun;22(2):149-66
XCT protein, Arabidopsis  0   *Arabidopsis Proteins Circadian Rhythm. Plant Cell 2008 May;20(5):1244-59
CIR1 protein, Arabidopsis  0   *Arabidopsis Proteins Circadian Rhythm. Plant J 2007 Aug;51(3):512-25
TIC protein, Arabidopsis  0   *Nuclear Proteins *Arabidopsis Proteins Circadian Rhythm. Plant Cell 2007 May;19(5):1522-36
PRR7 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins Circadian Rhythm. Plant Cell Physiol 2007 Jun;48(6):822-32
PRR5 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins Circadian Rhythm. Plant Cell Physiol 2007 Jun;48(6):822-32
clockwork orange protein, Drosophila  0   *Repressor Proteins *Drosophila Proteins Circadian Rhythm. Genes Dev 2007 Jul 1;21(13):1675-86
CIPC protein, mouse  0   *Carrier Proteins Circadian Rhythm. Nat Cell Biol 2007 Mar;9(3):268-75
LARK protein, mouse  0   *RNA-Binding Proteins Circadian Rhythm. Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1859-64
Dec1 protein, zebrafish  0   *Zebrafish Proteins *Basic Helix-Loop-Helix Transcription Factors Circadian Rhythm. Gene Expr Patterns 2006 Oct;6(8):919-27
PRR3 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins Circadian Rhythm. Plant Physiol 2006 Apr;140(4):1464-74
SRR1 protein, Arabidopsis  0   *Arabidopsis Proteins Circadian Rhythm. Genes Dev 2003 Jan 15;17(2):256-68
ARR3 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins Circadian Rhythm. Plant Cell 2006 Jan;18(1):55-69
Dbp protein, mouse  0   *DNA-Binding Proteins *Transcription Factors Circadian Rhythm Leucine Zippers.
EARLY FLOWERING 4 protein, Arabidopsis  0   *Arabidopsis Proteins Circadian Rhythm. Nature 2002 Sep 5;419(6902):74-7
ZGT protein, Nicotiana tabacum  0   *Plant Proteins Circadian Rhythm. Plant Cell 2001 Jun;13(6):1411-25
PER2 protein, human  0   *Period Circadian Proteins Circadian Rhythm. Science 2001 Feb 9;291(5506):1040-3
TOC1 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins Circadian Rhythm. Science. 2000 Aug 4;289(5480):768-71
LIN-42 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins Circadian Rhythm. Science 1999 Nov 5;286(5442):1141-6
TIM-1 protein, C elegans  0   *Caenorhabditis elegans Proteins Circadian Rhythm. Science 1999 Nov 5;286(5442):1141-6
KaiC protein, cyanobacteria  0   *Bacterial Proteins *Circadian Rhythm Signaling Peptides and Proteins Biological Clocks Circadian Rhythm Multigene Family. Science 1998 Sep 4;281(5382):1519-23
KaiB protein, cyanobacteria  0   *Bacterial Proteins *Circadian Rhythm Signaling Peptides and Proteins Biological Clocks Circadian Rhythm Multigene Family. Science 1998 Sep 4;281(5382):1519-23
KaiA protein, cyanobacteria  0   *Bacterial Proteins *Circadian Rhythm Signaling Peptides and Proteins Biological Clocks Circadian Rhythm Multigene Family. Science 1998 Sep 4;281(5382):1519-23
LHY protein, Arabidopsis  0   *DNA-Binding Proteins *Transcription Factors Circadian Rhythm Arabidopsis Proteins. Cell 1998 Jun 26;93(7):1219-29
CYCLE protein, Drosophila  0   *Drosophila Proteins *ARNTL Transcription Factors Circadian Rhythm Helix-Loop-Helix Motifs. Cell 1998 May 29;93(5):805-14
Pex protein, Synechococcus  0   *Bacterial Proteins Circadian Rhythm. J Bacteriol 1998 Apr;180(8):2167-74
CRG-1 protein, Drosophila  0   *Transcription Factors *Drosophila Proteins Circadian Rhythm. EMBO J 1997 Jul 1;16(13):3944-54
N-levulinoyl mannosamine  0   *Hexosamines Circadian Rhythm. Science 1997 May 16;276(5315):1125-8
Lark protein, Drosophila  0   *RNA-Binding Proteins *Drosophila Proteins Circadian Rhythm Repressor Proteins. J Neurobiol 1996 Sep;31(1):117-28
Dreg-3 protein, Drosophila  0   *Iron-Sulfur Proteins *Drosophila Proteins Circadian Rhythm. Curr Biol 1995 Dec 1;5(12):1424-36
Reg-2 protein, Drosophila  0   *Drosophila Proteins Circadian Rhythm. Curr Biol 1995 Dec 1;5(12):1424-36
nocturnin  0   *Nuclear Proteins *Transcription Factors Circadian Rhythm. Proc Natl Acad Sci U S A 1996 Dec 10;93(25):14884-8
timeless protein, Drosophila  0   *Drosophila Proteins Biological Clocks Circadian Rhythm. Science 1995 Nov 3;270(5237):805-8
Ppnr protein, mouse  0   *Proteins Circadian Rhythm Nerve Tissue Proteins. Brain Res Mol Brain Res 1994 Oct;26(1-2):197-206
ABI3 protein, Arabidopsis  0   *Arabidopsis Proteins Circadian Rhythm. Plant Cell 1994 Nov;6(11):1567-82
FRQ protein, Neurospora crassa  0   *Fungal Proteins Circadian Rhythm. EMBO J 1994 May 15;13(10):2257-66
luciferin-binding protein, dinoflagellate  0   *Calcium-Binding Proteins *Protozoan Proteins Circadian Rhythm. Proc Natl Acad Sci U S A 1994 Jun 7;91(12):5257-61
DBP protein, human  0   *DNA-Binding Proteins *Transcription Factors Circadian Rhythm Leucine Zippers. Cell 1990;61(2):279

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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