Definition: Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
do not routinely add when indexing coagulase negative organisms; index only when discussed
Pharmacological ActionCoagulants
Other names Staphylococcal Clumping Factor; Staphylocoagulase; Staphylococcus aureus strain 8325 4 of Coagulase; Factor, Staphylococcal Clumping; Clumping Factor, Staphylococcal; Staphylococcus aureus strain 8325-4 of Coagulase; Staphylococcus aureus strain 213 of Coagulase; Staphylococcus aureus clone pSCa2 of Coagulase; Clumping Factor (Staphylococcal)
