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Coated Pits, Cell-Membrane

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Definition: Specialized regions of the cell membrane composed of pits coated with a bristle covering made of the protein CLATHRIN. These pits are the entry route for macromolecules bound by cell surface receptors. The pits are then internalized into the cytoplasm to form the COATED VESICLES.  A 11 qualif except /cytol; /genet permitted; DF: COATED PITS   
See Also Clathrin
Examples Caveolae 		Other names Cell-Membrane Coated Pits; Bristle-Coated Pits; Pits, Cell-Membrane Coated; Pits, Bristle-Coated; Pit, Cell-Membrane Coated; Pit, Bristle-Coated; Coated Pits, Cell Membrane; Coated Pit, Cell-Membrane; Cell-Membrane Coated Pit; Cell Membrane Coated Pits; Bristle-Coated Pit; Bristle Coated Pits

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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