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Complement C4

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Definition: A glycoprotein that is important in the activation of CLASSICAL COMPLEMENT PATHWAY. C4 is cleaved by the activated COMPLEMENT C1S into COMPLEMENT C4A and COMPLEMENT C4B.     
Pharmacological Action Immunologic Factors
Examples Complement C4a; Complement C4b
Other names Pro-C4; Pro complement 4; Pro C4; Component, C4 Complement; Component 4, Complement; Complement, C4; Complement Component, C4; C4, Complement; Pro-complement 4; Complement Component 4; Complement C4, Precursor; Complement 4; C4 Complement Component; C4 Complement
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
complement C4A7  0   *Complement C4. Hum Hered 1988;38(6):363
C4a protein, mouse  0   *Complement C4 Complement C4 H-2 Antigens. J Exp Med 148(5):1186;1978
C4 protein, mouse  0   *Complement C4 H-2 Antigens. J Biol Chem 1985; 260:10936; J Exp Med 148(5):1186;1978; J Immunol 120(1):225;1978; Proc Natl Acad Sci USA 1979;76(11):5853; Proc Natl Acad Sci USA 1985; 82:5895

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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