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Cortisone

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Definition: A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)  /biosyn/physiol permitted   
Pharmacological Action Anti-Inflammatory Agents 		Other names Adreson
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
6 beta-hydroxycortisone  0   Cortisone/*analogs & derivatives. Steroids. 2003 Sep;68(7-8):693-703
FRALLE 93 protocol  0   Asparaginase Vincristine *Antineoplastic Combined Chemotherapy Protocols Cortisone Anthracyclines. Blood 1996 Jul 1;88(1):302-8
2-methylcortisone  3836-19-9   Cortisone/*analogs & derivatives. Steroids 1994 Feb;59(2):142-7
POG 8493 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cortisone/analogs & derivatives Cyclophosphamide Cytarabine Methotrexate Prednisone Vincristine 6-Mercaptopurine. Acta Haematol Pol 1993;24(2):131-8
18-hydroxycortisone  96737-55-2   Cortisone/*analogs & derivatives. J Steroid Biochem 1985;22(1):141
9-fluorocortisone  79-60-7   Cortisone/*analogs & derivatives. Postgrad Med J 1981;57(668):368
21-deoxycortisone  1882-82-2 17-hydroxypregn-4-ene-3,11,20-trione  Cortisone/*analogs & derivatives. Clin Endocrinol 10(4):367;1979
cortisone-4-ara-C  74517-56-9 Pregn-4-ene-3,11,20-trione, 17-hydroxy-21-(phosphonooxy)-, 5'-ester with 4-amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone  Cortisone/*analogs & derivatives Cytarabine/*analogs & derivatives. Biochem Biophys Res Commun 88(4):1223;1979
cortisone sulfate  912-25-4 17-hydroxy-21-(sulfooxy)pregn-4-ene-3,11,20- trione  Cortisone/*analogs & derivatives. J Clin Endocrinol Metab 1980;50(3):431; Neoplasma 26(2):205;1979
cortisone acetate  50-04-4   Cortisone/*analogs & derivatives.
Pharma Action Anti-Inflammatory Agents 		Clin Chim Acta 85:219;1978; Diabetologia 13(4):331;1977; Netherlands J Med 21(3):120;1978CORTONE; CORTISONE ACETATE
dutimelan  56939-84-5   Cortisone/*analogs & derivatives Drug Combinations Prednisolone/*analogs & derivatives. Chronobiol 1(suppl 1):282-449;1974
17,21-dihydroxy-5 beta-pregn-2-ene-1,11,20-trione  42947-81-9 Pregn-2-ene-1,11,20-trione, 17,21-dihydroxy-, (5beta)  Cortisone/*analogs & derivatives. J Am Chem Soc 13(0):1361;1973
4-pregnene-17 alpha,20 beta,21-triol-3,11-dione  3615-87-0   Cortisone/*analogs & derivatives.

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