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Crohn Disease

More information in Books or onNLM PubMed
Definition: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.  coord IM with ILEITIS (IM) or COLITIS (IM) only if site is particularly discussed; usually chronic so do not coord with CHRONIC DISEASE    Other names Ileocolitis; Ileitis, Terminal; Ileitis, Regional; Enteritis, Regional; Enteritis, Granulomatous; Colitis, Granulomatous; Crohns Disease; Crohn's Disease
 
SubstanceCAS Registry & nameCategoriesSource
Pediatric Crohn's disease  0   *Crohn Disease.
NOD2 protein, human  0   *Nod2 Signaling Adaptor Protein Crohn Disease. J Biol Chem 2001 Feb 16;276(7):4812-8
infliximab  0   *Antibodies, Monoclonal Arthritis, Rheumatoid Crohn Disease Tumor Necrosis Factor-alpha.
Pharma Action Anti-Inflammatory Agents ; Dermatologic Agents ; Gastrointestinal Agents ; Antirheumatic Agents
N Engl J Med 1997 Oct 9;337(15):1029-35REMICADE

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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