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Curare

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Definition: Plant extracts from several species, including genera STRYCHNOS and Chondodendron, which contain TETRAHYDROISOQUINOLINES that produce PARALYSIS of skeletal muscle. These extracts are toxic and must be used with the administration of artificial respiration.  /analogs: consider also CURARE-LIKE AGENTS see NEUROMUSCULAR NONDEPOLARIZING AGENTS   
Pharmacological Action Neuromuscular Nondepolarizing Agents; Nicotinic Antagonists
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
8,8'-dioxo-6,6'-azopurine  52583-98-9   *Purines Curare/antagonists & inhibitors Xanthine Oxidase/antagonists & inhibitors. J Med Chem 17(6):639;1974
caracurine  466-85-3   *Curare. Chem Biol Interactions 6(6):355;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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