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Cyclohexanecarboxylic Acids

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Definition:      
Examples Abscisic Acid; Aurintricarboxylic Acid; Chlorogenic Acid; Chorismic Acid; Dicyclomine; Quinic Acid; Shikimic Acid; Tilidine; Tranexamic Acid 		Other names Acids, Cyclohexanecarboxylic
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-(((3-carboxycyclohexyl)amino)carbonyl)-4-(3-(4-(4-phenoxybutoxy)phenyl)propoxy)benzoic acid  0   *Cyclohexanecarboxylic Acids *Phthalic Acids. J Pharmacol Exp Ther. 2011 Dec;339(3):768-78.
cyclohexanecarboxylic acid (3-(2,5-dimethylbenzyloxy)-4-(methanesulfonylmethylamino)phenyl)amide  0   *Cyclohexanecarboxylic Acids *Sulfonamides Cyclooxygenase 2 Inhibitors. J Steroid Biochem Mol Biol 2011 Aug;126(1-2):10-8
diisononyl 1,2-cyclohexanedicarboxylic acid  0   *Cyclohexanecarboxylic Acids *Dicarboxylic Acids. Int J Hyg Environ Health 2011 Jan;214(1):26-35
3-(((3-carboxycyclohexyl)amino)carbonyl)-4-(3-(4-(4-(cyclohexyloxy)butoxy)phenyl)propoxy)benzoic acid  0   *Cyclohexanecarboxylic Acids *Phthalic Acids. Br J Pharmacol 2010 May;160(2):399-409
MK 6892  0   *Cyclohexanecarboxylic Acids *Oxadiazoles. J Med Chem 2010 Mar 25;53(6):2666-70
4-(3-chloro-2-fluorophenoxy)-1-((6-(1,3-thiazol-2-ylamino)pyridin to 2-yl)methyl) cyclohexanecarboxylic acid  0   *Cyclohexanecarboxylic Acids *Thiazoles. Mol Cancer Ther 2010 Jan;9(1):157-66
VU 0155041  0   *Anilides *Cyclohexanecarboxylic Acids Receptors, Metabotropic Glutamate. Bioorg Med Chem Lett 2009 Sep 1;19(17):4967-70
2-amino-2-deoxyisochorismate  0   *Cyclohexanecarboxylic Acids. J Am Chem Soc 2009 Mar 18;131(10):3481-3
4-((2-(2-methylphenylamino)-6-benzoxazolylacetyl)-4-fluoro-2-pyrrolidinylmethoxy)cyclohexanecarboxylic acid  0   *Benzoxazoles *Cyclohexanecarboxylic Acids Integrin alpha4beta1/antagonists & inhibitors. Bioorg Med Chem 2009 Feb 1;17(3):1232-43
4-cyano-4-(2,3-dihydro-8-methoxy-1,4-benzodioxin-5-yl)cyclohexanecarboxylic acid  0   *Cyclohexanecarboxylic Acids *Dioxanes Cyclic Nucleotide Phosphodiesterases, Type 4/antagonists & inhibitors. Int Immunopharmacol 2009 Jan;9(1):55-62
cyclohexane-1,2-dicarboxylic acid  0   *Cyclohexanecarboxylic Acids *Dicarboxylic Acids. Angew Chem Int Ed Engl 2008;47(45):8634-7
1,2-bis(dodecylamido)cyclohexane  0   *Amides *Cyclohexanecarboxylic Acids. Electrophoresis 2008 Sep;29(18):3941-8
KW 4490  0   *Cyclohexanecarboxylic Acids *Dioxanes Cyclic Nucleotide Phosphodiesterases, Type 4/antagonists & inhibitors. Xenobiotica 2008 May;38(5):511-26
AMG 076  0   *Benzenesulfonates *Cyclohexanecarboxylic Acids. J Org Chem 2007 Dec 7;72(25):9648-55
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acid  0   *Cyclohexanecarboxylic Acids *Keto Acids. Biochemistry 2007 Sep 25;46(38):10979-89
4-fluorocyclohexanecarboxylic acid  0   *Cyclohexanecarboxylic Acids. Org Biomol Chem 2006 Nov 21;4(22):4071-3
5-amino-2-fluorocyclohex-3-enecarboxylic acid  0   *Amino Acids, Cyclic *Cyclohexanecarboxylic Acids 4-Aminobutyrate Transaminase/antagonists & inhibitors. Biochemistry 2006 Dec 5;45(48):14513-22
cyclohexanecarboxylic acid, (2-methoxyphenyl)-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)amide  0   *Cyclohexanecarboxylic Acids *Piperazines Receptor, Serotonin, 5-HT1A/agonists. J Pharmacol Exp Ther 2005 Oct;315(1):109-17
cyclohexanecarboxylic acid (2-(4-(2-bromo-5-methoxybenzyl)piperazin-1-yl)ethyl)-(2-trifluoromethoxyphenyl)amide  0   *Cyclohexanecarboxylic Acids *Piperazines Receptor, Serotonin, 5-HT1A/agonists. J Pharmacol Exp Ther 2005 Oct;315(1):109-17
S-2,2-dimethyl-6-methylenecyclohexanecarboxylic acid  0   *Cyclohexanecarboxylic Acids. Org Lett 2004 Feb 19;6(4):537-40
3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid  0   *Cyclohexanecarboxylic Acids *Cyclohexenes. Org Biomol Chem 2004 Jun 7;2(11):1592-6
E 121 compound  0   *Aniline Compounds *Cyclohexanecarboxylic Acids. Biopharm Drug Dispos 2003 Dec;24(9):397-407
HU 320  0   *Cyclohexanecarboxylic Acids Cannabidiol/*analogs & derivatives. Arthritis Rheum 2004 Mar;50(3):985-98
ceralure B1  0   *Cyclohexanecarboxylic Acids Pheromones. J Econ Entomol 2003 Dec;96(6);1719-23
3-ethyl-2,6,6-trimethyl-4-oxocyclohexanecarboxylic acid  0   *Cyclohexanecarboxylic Acids. Acta Crystallogr C 2002 Mar;58( Pt 3):o159-61
Cilomilast  0 4-cyano-4-(3-cyclopentoxy-4-methoxy-phenyl)-cyclohexane-1- carboxylic acid  *Cyclohexanecarboxylic Acids *Nitriles.
Pharma Action Phosphodiesterase 4 Inhibitors 		Lancet 2001 Jul 28;358(9278):265-70
ATL 146e  0   *Purines *Cyclohexanecarboxylic Acids. Drug Metab Dispos 2001 Apr;29(4 Pt 1):H67-74
methyl 4-O-feruloyl-5-O-caffeoylquinate  0   *Cyclohexanecarboxylic Acids. Phytochemistry 2001 Apr;56(7):729-32
4-O-feruloyl-5-O-caffeoylquinic acid  0   *Cyclohexanecarboxylic Acids. Phytochemistry 2001 Apr;56(7):729-32
1-((2-nitrophenyl)sulfonylamino)cyclohexanecarboxylic acid  0   *Benzamides *Cyclohexanecarboxylic Acids. Acta Crystallogr C 2000 Dec;56(Pt 12):1484-6
cypellocarpin C  0   *Cyclohexanecarboxylic Acids *Glucosides. J Nat Prod 2000 Sep;63(9):1253-7
cypellocarpin B  0   *Cyclohexanecarboxylic Acids *Glucosides. J Nat Prod 2000 Sep;63(9):1253-7
cypellocarpin A  0   *Cyclohexanecarboxylic Acids *Glucosides. J Nat Prod 2000 Sep;63(9):1253-7
oleuropeic acid  5027-76-9   *Cyclohexanecarboxylic Acids. J Nat Prod 2000 Sep;63(9):1253-7
methyl 2-(benzyloxycarbonylamino)-5-(tert-butoxycarbonylamino)cyclohexanecarboxylate  0   *Cyclohexanecarboxylic Acids *Cyclohexylamines. J Org Chem 2000 Jul 28;65(15):4766-9
2-hydroxy-3-(trimethylammonio)cyclohexanecarboxylic acid  0   *Quaternary Ammonium Compounds *Cyclohexanecarboxylic Acids Carnitine O-Palmitoyltransferase/antagonists & inhibitors. Bioorg Med Chem 1999 Aug;7(8):1505-11
3-methyl-4,5-cyclohexadiene-1,2-diol  0   *Cyclohexanecarboxylic Acids *Cyclohexenes. J Bacteriol 1999 May;181(9):2953-7
1-(2-(4-chlorophenyl)cyclopropylmethoxy)-3,4-dihydroxy-5-(3-imidazo(4,5-b)pyridin-1-yl-3-phenylacryloyloxy)cyclohexanecarboxylic acid  0   *Cyclohexanecarboxylic Acids. Diabetes 1998 Oct;47(10):1630-6
S 3483  0   *Cyclohexanecarboxylic Acids Glucose-6-Phosphatase/antagonists & inhibitors. Am J Physiol 1998 Jun;274(6 Pt 1):G1087-93
niduloic acid  0   *Cyclohexanecarboxylic Acids *Furans Cell Differentiation. J Antibiot (Tokyo) 1996 Dec;49(12):1189-95
2-aminocyclohexanecarboxylic acid  5691-19-0   *Cyclohexanecarboxylic Acids *Cyclohexylamines. Nature 1997 Jan 9;385(6612):113-5
N-(5-((1'-phenyl-1'-cyclohexylacetoxy)methyl)-2-furfuryl)pentanamine  0   *Cyclohexanecarboxylic Acids *Furans. J Med Chem 1994 Dec 9;37(25):4278-87
1-(5-((1'-phenyl-1'-cyclohexylacetoxy)methyl)-2-furfuryl)piperidine  0   *Cyclohexanecarboxylic Acids *Furans. J Med Chem 1994 Dec 9;37(25):4278-87
N-methyl-N-(5-((1'-phenyl-1'-cyclohexylacetoxy)methyl)-2-furfuryl)cyclohexylamine  0   *Furans *Cyclohexanecarboxylic Acids. J Med Chem 1994 Dec 9;37(25):4278-87
4-amidinocyclohexanecarboxylic acid 4-tert-butylphenyl ester  153235-96-2   *Cyclohexanecarboxylic Acids. Biol Pharm Bull 1993 Sep;16(9):829-33
gevilon  7009-49-6   *Cyclohexanecarboxylic Acids. Mater Med Pol 1992 Apr-Jun;24(2):91-5
methyl 4-(benzylamino)-6-methyl-2-oxocyclohex-3-en-1-oate  149221-05-6   *Cyclohexanecarboxylic Acids *Benzylamines. J Med Chem 1993 Jul 9;36(14):1947-55
ADD 196022  142458-16-0   *Cyclohexanecarboxylic Acids *Cyclohexylamines. J Med Chem 1993 Jul 9;36(14):1947-55
idrapril  127420-24-0 Cyclohexanecarboxylic acid, 2-(((2-(hydroxyamino)-2-oxoethyl)methylamino)carbonyl)-, (1S-cis)  *Cyclohexanecarboxylic Acids *Hydroxylamines. J Cardiovasc Pharmacol 1992 Jul;20(1):139-46
1-cyclohexenecarboxylic acid  636-82-8   *Cyclohexanecarboxylic Acids. J Bacteriol 1992 Jun;174(12):3850-54
hexahydrophthalic acid  1687-30-5   *Cyclohexanecarboxylic Acids. J Chromatogr 1991 Dec 6;572(1-2):117-31
4-hydroxycyclohexanecarboxylic acid  3685-26-5   *Cyclohexanecarboxylic Acids. Clin Chem 1991;37(7):1301
4-(3-amino-2-oxoazetidinonyl-1)methylcyclohexanecarboxylic acid  137232-05-4   *Azetidines *Cyclohexanecarboxylic Acids beta-Lactamases/antagonists & inhibitors. Yao Hsueh Hsueh Pao 1990;25(5):340
MDL 28753  129509-46-2   *Sulfides *Cyclohexanecarboxylic Acids. J Pharmacol Exp Ther 1990;254(1):192
6-methoxycarbonyl-3-cyclohexene-1-carboxylic acid  88335-93-7   *Cyclohexanecarboxylic Acids *Cyclohexenes. Chem Pharm Bull (Tokyo) 1990;38(2):350
candoxatrilat  123898-42-0 Cyclohexanecarboxylic acid, 4-(((1-(2-carboxy-3-(2-methoxyethoxy)propyl)cyclopentyl)carbonyl)amino)-, cis-(+-)  *Cyclohexanecarboxylic Acids Neprilysin/antagonists & inhibitors.
Pharma Action Protease Inhibitors 		Lancet 1989;2(8663):591
adozelesin  123219-86-3   *Cyclohexanecarboxylic Acids *Indoles *Cyclohexenes.
Pharma Action Antineoplastic Agents, Alkylating 		Mutat Res 1989;223(2):129
prephenyllactate  117580-15-1   *Lactates *Cyclohexanecarboxylic Acids *Cyclohexenes. J Biol Chem 1988;263(33):17284
cyclohexane-1,2-dicarboxylic acid bis(oxiranylmethyl) ester  5493-45-8 1,2-Cyclohexanedicarboxylic acid, bis(oxiranylmethyl) ester  *Cyclohexanecarboxylic Acids *Epoxy Compounds Allergens. Contact Dermatitis 1986;15(2):66
2'-(N,N-dimethylamino)-6-naphthoyl-4-cyclohexanecarboxylic acid  107408-10-6   *Cyclohexanecarboxylic Acids. Nature 1986;319(6048):70
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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