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Cyproheptadine

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Definition: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.  a histamine H1 antag & serotonin antag   
Pharmacological Action Anti-Allergic Agents; Antipruritics; Gastrointestinal Agents; Histamine H1 Antagonists; Serotonin Antagonists
Examples Loratadine 		Other names Viternum; Peritol; Periactin; Dihexazin; AnterganDrugs* : CYPROHEPTADINE HYDROCHLORIDE; PERIACTIN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
rupatadine  156611-76-6   Cyproheptadine/*analogs & derivatives Platelet Activating Factor/antagonists & inhibitors. J Pharmacol Exp Ther 1997 Jan;280(1):114-21
desmethylcyproheptadine 10,11-epoxide  54191-03-6   Cyproheptadine/*analogs & derivatives. Cell Biol Toxicol 1989;5(2):129
cyproheptadine 10,11-epoxide  54191-04-7   Cyproheptadine/*analogs & derivatives. Cell Biol Toxicol 1989;5(2):129
3-methoxycyproheptadine  77263-46-8   Cyproheptadine/*analogs & derivatives. J Pharmacol Exp Ther 1988;247(2):796
Sch 399  98125-69-0   *Dextromethorphan *Pseudoephedrine Cyproheptadine/*analogs & derivatives Drug Combinations. Clin Ther 1984;6(4):475
azatadine maleate, pseudoephedrine sulfate drug combination  0   *Pseudoephedrine Cyproheptadine/*analogs & derivatives Drug Combinations.
Pharma Action Histamine H1 Antagonists ; Sympathomimetics 		Pharmatherapeutica 1984;3(10):657
L 646462  89149-85-9 5H-Dibenzo(a,d)cycloheptene-3-carboxylic acid, 5-(1-methyl-4-piperidinylidene)-, (3-methyl-2,5-dioxo-1-imidazolidinyl)methyl ester, (-)  Cyproheptadine/*analogs & derivatives. J Pharmacol Exp Ther 1984;229(3):775
desmethylcyproheptadine  14051-46-8   Cyproheptadine/*analogs & derivatives. J Endocrinol 1983;96(3):395
MK 711  63141-67-3   Cyproheptadine/*analogs & derivatives Appetite/drug effects. Drug Metab Dispos 1981;9(5):428
cyproheptadine glucuronide  66167-97-3 Piperidinium, 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-beta-D-glucopyranuronosyl-1-methyl  Cyproheptadine/*analogs & derivatives. Drug Metab Dispos 1980;8(6):422
cyproheptadinium methiodide  74927-10-9   Cyproheptadine/*analogs & derivatives. J Med Chem 1980;23(11):1255
1-cyclopropylmethyl-4-(3-trifluoromethylthio-5H-dibenzo(a,d)cyclohepten-5-ylidene)piperidine  0   Cyproheptadine/*analogs & derivatives. J Med Chem 20(8):1013;1977
azatadine  3964-81-6 6,11-dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine  Cyproheptadine/*analogs & derivatives.
Pharma Action Histamine H1 Antagonists 		Agents Actions 4(4):264;1974; J Lab Clin Med 90(4):638;1977; Med Lett 19(19):77;1977; Radioisotopes 26(1):33;1977TRINALIN; OPTIMINE

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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