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Cysteinyldopa

More information in Books or onNLM PubMed
Definition: Found in large amounts in the plasma and urine of patients with malignant melanoma. It is therefore used in the diagnosis of melanoma and for the detection of postoperative metastases. Cysteinyldopa is believed to be formed by the rapid enzymatic hydrolysis of 5-S-glutathionedopa found in melanin-producing cells.  /biosyn /physiol permitted    Other names 5 S Cysteinyldopa; 5-S-Cysteinyldopa
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cysteinyldopa-melanin  0   *Melanins Cysteinyldopa/*analogs & derivatives. J Phys Chem B 2006 Jul 20;110(28):13985-90
5-S-glutathionyl-alpha-methyldopa  0   Cysteinyldopa/*analogs & derivatives. Chem Biol Interact 1994 Jan;90(1):87-99
5-S-glutathionyldopamine  0   Cysteinyldopa/*analogs & derivatives. Chem Biol Interact 1994 Jan;90(1):87-99
5-S-cysteinyl-glycyl-dopa  110823-49-9   Cysteinyldopa/*analogs & derivatives. Anal Biochem 1987;165(1):167
5-S-cysteinyl-3,4-dihydroxyphenylacetic acid  102986-13-0   Cysteinyldopa/*analogs & derivatives. Neuropharmacology 1986;25(4):451
6-S-cysteinyldopa  64003-39-0 L-Tyrosine, 2-((2-amino-2-carboxyethyl)thio)-5-hydroxy-, (R)  Cysteinyldopa/*analogs & derivatives. Nippon Hifuka Gakkai Zasshi 1982;92(1):53
2-S-cysteinyldopa  25565-17-7   *Cysteinyldopa Isomerism. Nippon Hifuka Gakkai Zasshi 1982;92(1):53
2,5-S,S-dicysteinyldopa  57954-84-4 L-Tyrosine, 2,5-bis((2-amino-2-carboxyethyl)thio)-3-hydroxy-, (R-(R*,R*))  Cysteinyldopa/*analogs & derivatives. Nippon Hifuka Gakkai Zasshi 1982;92(1):53
glutathionyldopa  55136-58-8 Glycine, N-(S-(5-(2-amino-2-carboxyethyl)-2,3-dihydroxyphenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (S)  Cysteinyldopa/*analogs & derivatives. Acta Derm Venereol (Stockh)1981;61(4):339

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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