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Daunorubicin

More information in Books or onNLM PubMed
Definition: A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.     
Pharmacological Action Antibiotics, Antineoplastic
Examples Carubicin; Doxorubicin; Idarubicin; Nogalamycin 		Other names Rubomycin; Rubidomycin; Daunomycin; NSC82151; NSC 82151; Hydrochloride, Daunorubicin; Dauno Rubidomycine; NSC-82151; Daunorubicin Hydrochloride; Daunoblastine; Daunoblastin; Dauno-Rubidomycine; CerubidineDrugs* : CERUBIDINE; DAUNORUBICIN HYDROCHLORIDE; DAUNOXOME
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
((N-morpholine)metylene)daunorubicin  0   *Morpholines Daunorubicin/*analogs & derivatives Antibiotics, Antineoplastic. Acta Pol Pharm. 2011 Sep-Oct;68(5):759-63
7-(3-amino-4-O-(mycarosyl)-2,3,6-trideoxyhexopyranosyl)daunorubicinone  0   *Disaccharides Daunorubicin/*analogs & derivatives. Carbohydr Res 2011 May 15;346(7):949-55
oxazolinodaunorubicin  0   Daunorubicin/*analogs & derivatives. Invest New Drugs 2010 Oct;28(5):600-8
4'-O-(oleandrosyl)daunorubicin  0   *Disaccharides Daunorubicin/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc 2010 May;75(5):1511-5
HAD protocol  0   *Cytarabine *Daunorubicin *Harringtonines Antineoplastic Combined Chemotherapy Protocols. Am J Hematol 2009 Jul;84(7):422-7
4'-O-(a-l-cladinosyl)daunorubicin  0   Daunorubicin/*analogs & derivatives. J Photochem Photobiol B 2009 Jun 3;95(3):162-9
EORTC GIMEMA AML-10 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin Etoposide Mitoxantrone Idarubicin. Haematologica 2007 May;92(5):605-11
MRC AML 10 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Amsacrine Cytarabine Daunorubicin Etoposide Mitoxantrone. Pediatr Blood Cancer 2007 Mar;48(3):262-7
POG-8498 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Azacitidine Cytarabine Daunorubicin Etoposide Methotrexate Prednisone Thioguanine Vincristine 6-Mercaptopurine. Pediatr Blood Cancer 2007 Mar;48(3):262-7
3'-azidodaunorubicin  0   *Azides Daunorubicin/*analogs & derivatives. J Med Chem 2006 Feb 9;49(3):932-41
WP 762  0   Daunorubicin/*analogs & derivatives. J Med Chem 2005 Dec 29;48(26):8209-19
ALL-BFM-95 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Cyclophosphamide Cytarabine Daunorubicin Prednisolone Vincristine 6-Mercaptopurine. Orv Hetil. 2005 Jan 9;146(2):75-80
9-dehydroxydaunomycin  0   Daunorubicin/*analogs & derivatives. Nucleic Acids Res 2004;32(15):4696-703
bisdaunomycin  0   Daunorubicin/*analogs & derivatives. Nucleic Acids Res 2004;32(15):4696-703
11mer daunomycin-conjugated GT  0   *Daunorubicin *Oligonucleotides. Nucleic Acids Res 2004;32(8) (dup#3):2396-410
AML91 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin Deoxyadenosines Etoposide. J Pediatr Hematol Oncol 2003 Sep;25(9):696-703
ABCDV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Betamethasone Daunorubicin Cyclophosphamide Cytarabine Vincristine. Bone Marrow Transplant 2002 Dec;30(12):971-3
PETHEMA ALL-96 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Cyclophosphamide Daunorubicin Prednisolone Vincristine. Cancer Genet Cytogenet 2003 Jan 1;140(1):58-61
HDAC protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin. Blood 2002 Dec 15;100(13):4325-36
ADA protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Cytarabine Daunorubicin. Leukemia 2001 Jun;15(6):898-902
feudomycinone C  0   Daunorubicin/*analogs & derivatives. Metab Eng 2001 Jan;3(1):49-63
4-demethoxy-3'-deamino-4'-deoxy-4'-aminodaunorubicin  0   Daunorubicin/*analogs & derivatives DNA Topoisomerases, Type II/antagonists & inhibitors. Cancer Res 2000 Jul 15;60(14):3770-6
7-O-(3-chloro-2,3,6-trideoxy-4-O-propanoyl-lyxo-hexopyranosyl)daunomycinone  0   Daunorubicin/*analogs & derivatives. Chem Pharm Bull (Tokyo) 2000 Jan;48(1):150-3
7-O-(4-O-acetyl-3-iodo-2,3,6-trideoxy-arabino-hexopyranosyl)daunomycinone  0   Daunorubicin/*analogs & derivatives. Chem Pharm Bull (Tokyo) 2000 Jan;48(1):150-3
N-cyanomethyl-N-(2-methoxyethyl)daunomycin  0   Daunorubicin/*analogs & derivatives. Eur J Biochem 2000 Jan;267(2):457-64
PNU 169884  0   Daunorubicin/*analogs & derivatives. J Chromatogr A 1999 Aug 27;854(1-2):13-22
4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulfonyldaunorubicin  0   Daunorubicin/*analogs & derivatives. J Chromatogr A 1999 Aug 27;854(1-2):13-22
7-O-(3-amino-2,3,6-trideoxy-6,6,6-trifluoro-lyxo-hexopyranosyl)daunomycinone  0   Daunorubicin/*analogs & derivatives. Carbohydr Res 1999 Jul 20;320(1-2):8-18
7-O-(2,6-dideoxy-2-fluoro-5-C-(trifluoromethyl)talopyranosyl)daunomycinone  0   Daunorubicin/*analogs & derivatives. Carbohydr Res 1999 Mar 31;316(1-4):47-5
daunoform  0   Daunorubicin. Chem Res Toxicol 1999 Jul;12(7):588-96
NSC 284682  0   Daunorubicin/*analogs & derivatives. J Natl Cancer Inst 1999 Feb 3;91(3):236-44
N-(4-(daunorubicin-N-carbonyl-oxymethyl)phenyl)-O-glucuronyl carbamate  0   Daunorubicin/*analogs & derivatives. Br J Cancer 1998 Dec;78(12):1600-6
4-methoxydaunorubicin  0   Daunorubicin/*analogs & derivatives. Appl Radiat Isot 1998 Jul;49(7):811-3
daunomycin semiquinone  0   Daunorubicin/*analogs & derivatives. Arch Biochem Biophys 1997 Oct 1;346(1):91-5
WP 652  186131-38-4   Daunorubicin/*analogs & derivatives. Biochemistry 1997 Jul 22;36(29):8663-70
AIEOP 8703 protocol  0   Asparaginase *Antineoplastic Combined Chemotherapy Protocols Leucovorin Daunorubicin Methotrexate Prednisone Vincristine 6-Mercaptopurine. Blood 1997 Aug 1;90(3):1226-32
AML92 protocol  0   Tretinoin *Antineoplastic Combined Chemotherapy Protocols Cytarabine/analogs & derivatives Daunorubicin. Blood 1995 Mar 1;85(5):1202-6
WP 631  0   Daunorubicin/*analogs & derivatives. J Med Chem 1997 Jan 31;40(3):261-6
DrrA protein, Streptomyces peucetius  0   *Bacterial Proteins *ATP-Binding Cassette Transporters Daunorubicin Doxorubicin. J Bacteriol 1997 Feb;179(3):569-75
DAT-COAP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Cytarabine Daunorubicin Prednisone Thioguanine Vincristine. Leuk Res 1996 Nov-Dec;20(11-12):987-8
BF-9 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin Etoposide Mitoxantrone Thioguanine. Eur J Obstet Gynecol Reprod Biol 1995 Dec;63(2):139-41
M-DOMP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Daunorubicin Methotrexate Prednisone Vincristine 6-Mercaptopurine. Leuk Lymphoma 1996 Jun;22(1-2):71-6
WP 400  0   Daunorubicin/*analogs & derivatives Stereoisomerism. Eur J Biochem 1996 Sep 1;240(2):331-5
MSK-NY-II protocol, modified  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Cyclophosphamide Daunorubicin Methotrexate Prednisolone Vincristine. Med Pediatr Oncol 1996 Sep;27(3):139-44
DCTER protocol  0   Etoposide *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin Dexamethasone Thioguanine. Blood 1996 Jun 15;87(12):4979-89
HR-2 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Daunorubicin Dexamethasone Ifosfamide Methotrexate Prednisolone Thioguanine Vindesine. Blood 1996 Apr 15;87(8):3143-50
ALHR88 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Cytarabine Daunorubicin Methotrexate Prednisolone Vincristine. Med Pediatr Oncol 1996 Jan;26(1):10-9
AL851 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Daunorubicin Prednisolone Vincristine. Med Pediatr Oncol 1996 Jan;26(1):10-9
daunophilin  150825-43-7 Daunophilin  *Daunorubicin. Neoplasma 1993;40(3):161-6
AML8A protocol  0   *Antineoplastic Combined Chemotherapy Protocols Amsacrine Cytarabine Daunorubicin. Nouv Rev Fr Hematol 1993 Feb;35(1):15-6
BHAC-DMPV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine/analogs & derivatives Daunorubicin Prednisolone Vincristine 6-Mercaptopurine. Leuk Lymphoma 1993 Jan;9(1-2):43-8
DCVP-1-asp protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Cytarabine Daunorubicin Prednisolone Vincristine. Rinsho Ketsueki 1993 Mar;34(3):307-12
LALA 87 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Daunorubicin/analogs & derivatives Methotrexate Steroids Vincristine. Leuk Lymphoma 1992 Nov;8(4-5):415-9
AIEOP protocol 8202  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Daunorubicin Methotrexate Prednisone Vincristine 6-Mercaptopurine. Haematologica 1992 Sep-Oct;77(5):427-9
non-Hodgkin's lymphoma protocol 8503  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Daunorubicin Methotrexate Prednisolone Vincristine 6-Mercaptopurine Trimethoprim-Sulfamethoxazole Combination. Br J Haematol 1992 Oct;82(2):310-6
7+3 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Cytarabine Daunorubicin 6-Mercaptopurine. Ter Arkh 1992;64(8):87-9
RACOP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Cytarabine Daunorubicin Prednisolone Vincristine. Ter Arkh 1992;64(8):82-7
AIEOP acute lymphoblastic leukemia protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Cyclophosphamide Cytarabine Daunorubicin Methotrexate Prednisone Vincristine 6-Mercaptopurine. Haematologica 1992 Jan-Feb;77(1):49-53
DATV regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin Thioguanine Vincristine. Chung Hua Nei Ko Tsa Chih 1992 Mar;31(3):146-8
GAP-POMP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin Methotrexate Prednisone Vincristine 6-Mercaptopurine. Am J Pediatr Hematol Oncol 1992 May;14(2):136-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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