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Deoxycytidine Kinase

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Definition: An enzyme that catalyzes reversibly the phosphorylation of deoxycytidine with the formation of a nucleoside diphosphate and deoxycytidine monophosphate. Cytosine arabinoside can also act as an acceptor. All natural nucleoside triphosphates, except deoxycytidine triphosphate, can act as donors. The enzyme is induced by some viruses, particularly the herpes simplex virus (HERPESVIRUS HOMINIS). EC 2.7.1.74.      Other names Kinase, Deoxycytidine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
thymidine-5'-thiosulfate  0   *Thiosulfates Thymidine/*analogs & derivatives Deoxycytidine Kinase/agonists. Biochem Pharmacol 2003 Feb 15;65(4):563-71
arabinosylcytosine kinase  EC 2.7.1.-   *Deoxycytidine Kinase. Cancer Res 32(12):2711;1972; Gann 69(4):565;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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