encyclopedia of medical concepts
ψ 
ψ 
ψ 

Deoxyuridine

More information in Books or onNLM PubMed
Definition: 2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.  an antimetabolite   
Pharmacological Action Antimetabolites
Examples Bromodeoxyuridine; Floxuridine; Idoxuridine 		Other names (beta 1-(2-Deoxyribopyranosyl))thymidine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
LY2334737  0   Deoxyuridine/*analogs & derivatives. Clin Cancer Res. 2011 Sep 15;17(18):6071-82
5-(1-phenyl-1,2,3-triazol-4-yl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. J Org Chem. 2011 Aug 5;76(15):6177-87
2'-azido-5-cyano-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Phys Chem Chem Phys. 2011 Apr 7;13(13):5926-30
5-phenylselenylmethyl-2'-deoxyuridine  0   *Organoselenium Compounds Deoxyuridine/*analogs & derivatives. Bioorg Med Chem Lett 2011 Feb 15;21(4):1151-4
5-methylselenylmethyl-2'-deoxyuridine  0   *Organoselenium Compounds Deoxyuridine/*analogs & derivatives. Bioorg Med Chem Lett 2011 Feb 15;21(4):1151-4
5-iodo-3'-O-(17beta-succinyl-5alpha-androstan-3-one)-2'-deoxyuridine  0   *Androstanols Deoxyuridine/*analogs & derivatives. J Med Chem. 2009 Aug 27;52(16):5124-43
5-tripropargylamine-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Chembiochem. 2008 Sep 22;9(14):2305-16
5-(3-(2-anthracenecarboxamido)propynyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2007;(51):23-4
AraC-L-5FdU  0   Deoxyuridine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1619-24
5-dimethylaminopropargyl deoxyuridine  0   *Methylamines Deoxyuridine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1283-6
3'-fluoro-5-iodo-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives Iodine Radioisotopes. Nucl Med Biol 2007 Apr;34(3):273-81
5-(3-(1-pyrenecarboxamido)propynyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. J Am Chem Soc 2004 Apr 21;126(15):4820-7
1'-pivaloyl-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2005;(49):179-80
5-carboxyvinyl-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2005;(49):143-4
5-formyl-2'-deoxyuridine-3',5'-diacetate  0   Deoxyuridine/*analogs & derivatives. Bioorg Chem 2007 Apr;35(2):121-36
N(3)-anisoyl-6-aza-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Acta Crystallogr C. 2007 Mar;63(Pt 3):o173-6
6-aza-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Acta Crystallogr C. 2007 Mar;63(Pt 3):o173-6
5-Propynylamino alpha-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Bioorg Med Chem Lett. 2007 Feb 15;17(4):951-4
5-phenylthio-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Org Lett 2006 Jun 8;8(12):2527-30
5-((6-guanidiniohexylcarbamoyl)methyl)-2'deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Angew Chem Int Ed Engl. 2005 Oct 21;44(41):6682-5
5'-(benzhydryloxybis(trimethylsilyloxy))silyl-2'-methylseleno-2'-deoxyuridine phosphoramidite  0   *Organoselenium Compounds Deoxyuridine/*analogs & derivatives Selenium Silicon. Org Lett 2005 Dec 8;7(25):5645-8
5-((perylen-3-yl)methoxyprop-1-ynyl)-2'-deoxyuridine  0   Deoxyuridine. Chembiochem 2006 May;7(5):810-6
5-(perylen-3-ylethynyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Chembiochem. 2006 May;7(5):810-6
3'-5-(3-acylamidopropargyl)-3'-amino-2',3'-dideoxyuridine  0   Deoxyuridine/*analogs & derivatives. J Org Chem. 2006 Feb 3;71(3):1060-7
5-(10-methyl-phenothiazin-3-yl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Chemistry. 2005 Mar 4;11(6):1871-6
5-(dimethoxymethyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. J Med Chem 2006 Jun 1;49(11):3377-82
5-(2'-deoxyuridinyl)methyl  0   Deoxyuridine/*analogs & derivatives. Org Lett. 2004 Dec 23;6(26):5011-3
5-cyanovinyldeoxyuridine  0   Deoxyuridine/*analogs & derivatives. Org Lett 2005 Jul 7;7(14):2853-6
5-(pyren-1-yl)-2'-deoxyuridine  0   *Pyrenes Deoxyuridine/*analogs & derivatives. Biochemistry 2005 Sep 6;44(35):11749-57
5-(1-hexynyl)deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Magy Onkol 2004;48(3):221-7
guanylyl-(3',3')-(2'-amino-2'-deoxyuridine)  0   Deoxyuridine/*analogs & derivatives Guanine/*analogs & derivatives. J Am Chem Soc. 2005 Feb 16;127(6):1826-32
4-O-methyl-5-formylmethyl-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2003;22(1):71-84
3'-5'-di-O-(1-adamantyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2003;22(1):13-9
5,6-dihydro-2'-deoxyuridin-6-yl  0   Deoxyuridine/*analogs & derivatives. J Org Chem 2003 May 30;68(11):4275-80
5-(((6-((carbazol-9-yl)acetamido)hexyl)aminocarbonyl)vinyl)deoxyuridine  0   *Carbazoles Deoxyuridine/*analogs & derivatives. Biosci Biotechnol Biochem 2003 Apr;67(4):155-6
3'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Antivir Chem Chemother 2002 Nov;13(6):363-70
5',6-cyclo-5-hydroxy-5,6-dihydro-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Chembiochem 2002 Jun 3;3(6):534-42
5-iodo-4'-thio-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives Iodine Radioisotopes Tomography, Emission-Computed, Single-Photon. J Nucl Med 2002 Sep;43(9):1218-26
dicobalt hexacarbonyl 5-p-tolylethynyl-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives Cobalt. Chem Commun (Camb) 2002 Feb 21;(4):332-3
5-cyano-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Bioorg Med Chem Lett 2001 Sep 17;11(18):2453-5
2'-deoxy-5-(trifluoromethyl)uridine  0   Deoxyuridine/*analogs & derivatives. Bioorg Med Chem Lett 2001 Sep 17;11(18):2453-5
5-(phenylthiomethyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2001 Apr-Jul;20(4-7):967-71
5-(N-(beta-ferrocenyl-propanoyl)3-amino-propyn-1-yl)-2',3'-dideoxyuridine 5'-triphosphate  0   *Deoxyuracil Nucleotides *Dideoxynucleotides Deoxyuridine/*analogs & derivatives. Bioconjug Chem 2001 May-Jun;12(3):396-405
N-(2-(2'- N-acetylamino-2'-deoxyglucopyranosyl)ethyl)-N'-(5'-deoxyuridin-5'-yl)-2,3-dihydroxysuccinamide  0   *Glucosides Deoxyuridine/*analogs & derivatives.
K-11-dUTP  0   *Organometallic Compounds Deoxyuridine/*analogs & derivatives Europium. Nucleosides Nucleotides Nucleic Acids 2000 Sep;19(9):1463-74
Ro 09-3431  0   Deoxyuridine/*analogs & derivatives. Clin Cancer Res 2000 Jun;6(6):2288-94
5-(2-(4-N,N-dimethylaminophenyl)ethyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2000 May-Jun;19(5-6):851-66
5-(3-(N-methylphenylamino)propanoyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2000 May-Jun;19(5-6):851-66
5-amino-2'-deoxyuridine  5536-30-1   Deoxyuridine/*analogs & derivatives. Chem Pharm Bull (Tokyo) 2000 Apr;48(4):631-4
2'-amino-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Org Lett 1999 Dec 16;1(12):2021-4
5-(S-(2,4-dinitrophenyl)-thio)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. J Mol Recognit 1999 Nov-Dec;12(6):337-45
5-(1-propargylamino)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleic Acids Res 1999 Apr 15;27(8):1802-9
5-(2-amino-2-deoxyglucopyranosyloxymethyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Bioorg Med Chem Lett 1999 Jan 18;9(2):201-4
guanylyl(3'-6')-6'-deoxyhomouridine  0   Deoxyuridine/*analogs & derivatives Phosphonic Acids. Biochemistry 1999 Feb 23;38(8):2452-61
2'-deoxy-2'-hydroxylaminouridine  0   *Hydroxylamines Deoxyuridine/*analogs & derivatives. Bioorg Med Chem Lett 1998 Jul 21;8(14):1913-8
2'-deoxy-2'-aminouridine  0   Deoxyuridine/*analogs & derivatives. Biochem Mol Biol Int 1998 Oct;46(3):597-606
2'-azido-2'-deoxyuridine  26929-65-7   *Azides Deoxyuridine/*analogs & derivatives Ribonucleotide Reductases/antagonists & inhibitors. Nucleosides Nucleotides 1998 Jun;17(6):1077-88
5'-amino-5'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Nucleic Acids Symp Ser 1997;(37):9-10
5-(N-(3-(N,N-bis(3-aminopropyl)amino)propyl)carbamoyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Bioconjug Chem 1998 Jan-Feb;9(1):33-9
5-(N-(2-(N,N-bis(2-aminoethyl)amino)ethyl)carbamoyl)-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives. Bioconjug Chem 1998 Jan-Feb;9(1):33-9
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy