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Desmosomes

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Definition: A type of junction that attaches one cell to its neighbor. One of a number of differentiated regions which occur, for example, where the cytoplasmic membranes of adjacent epithelial cells are closely apposed. It consists of a circular region of each membrane together with associated intracellular microfilaments and an intercellular material which may include, for example, mucopolysaccharides. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990; Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)  A 11 qualif except /cytol; /genet permitted    Other names Desmosome
 
SubstanceCAS Registry & nameCategoriesSource
PPL protein, human  0   *Plakins Desmosomes.
Pnn protein, mouse  0   *Nuclear Proteins *Cell Adhesion Molecules Desmosomes.
Dsc2 protein, mouse  0   *Membrane Glycoproteins Desmosomes.
Dsc1 protein, mouse  0   *Membrane Glycoproteins Desmosomes.
Ahnak protein, rat  0   *Membrane Proteins *Neoplasm Proteins Desmosomes.
Ahnak protein, mouse  0   *Membrane Proteins *Neoplasm Proteins Desmosomes.
DSG4 protein, human  0   *Desmogleins Desmosomes. J Invest Dermatol 2003 Apr;120(4):523-30
Ppl protein, mouse  0   *Plakins Desmosomes. J Cell Biol 1997 Dec 29;139(7):1835-49
CDSN protein, human  0   *Glycoproteins Desmosomes. J Biol Chem 1997 Dec 12;272(50):31770-6
PNN protein, human  0   *Nuclear Proteins *Cell Adhesion Molecules Desmosomes. J Cell Biol 1996 Nov;135(4):1027-42
Dsc3 protein, mouse  161026-82-0   *Membrane Glycoproteins Desmosomes Cadherins. Genomics 1994 Jun;21(3):510-6
DSC2 protein, human  0   *Desmocollins Desmosomes. Int J Dev Biol 1993 Mar;37(1):101-10
AHNAK protein, human  0   *Membrane Proteins *Neoplasm Proteins Desmosomes. J Cell Biol 1989;109(4 Pt 1):1511; Proc Natl Acad Sci USA 1992 Jun 15;89(12):5472-6
band 5 protein, desmosomal  0   *Membrane Proteins Blood Proteins Desmosomes. J Cell Biol 1985;101(4):1442

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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