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Diabetes Mellitus, Type 1

More information in Books or onNLM PubMed
Definition: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.  MICE, INBRED NOD are a common model for this disease   
See Also Mice, Inbred NOD
Examples Wolfram Syndrome 		Other names IDDM; Diabetes, Autoimmune; Diabetes Mellitus, Sudden-Onset; Diabetes Mellitus, Ketosis-Prone; Diabetes Mellitus, Juvenile-Onset; Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Brittle; Sudden-Onset Diabetes Mellitus; Mellitus, Sudden-Onset Diabetes; Ketosis-Prone Diabetes Mellitus; Juvenile-Onset Diabetes Mellitus; Insulin-Dependent Diabetes Mellitus; Diabetes Mellitus, Sudden Onset; Diabetes Mellitus, Ketosis Prone; Diabetes Mellitus, Juvenile Onset; Diabetes Mellitus, Insulin Dependent; Diabete, Autoimmune; Brittle Diabetes Mellitus; Autoimmune Diabete; Type 1 Diabetes Mellitus
 
SubstanceCAS Registry & nameCategoriesSource
InsB9-23 peptide  0   *Peptides Diabetes Mellitus, Type 1/therapy. Clin Immunol. 2012 Mar;142(3):402-3
Bangstad syndrome  0   *Ataxia *Diabetes Mellitus, Type 1 *Dwarfism *Goiter Gonads/abnormalities.
Wolcott-Rallison syndrome  0   *Diabetes Mellitus, Type 1 *Osteochondrodysplasias Epiphyses/abnormalities.
DiaPep 277  0   *Peptide Fragments *Chaperonin 60 Diabetes Mellitus, Type 1. JAMA 2002 Feb 13;287(6):701-2
IDDMK1,2 22 superantigen, human  0   *Membrane Proteins *Superantigens Diabetes Mellitus, Type 1. Cell 1997 Jul 25;90(2):303-13
serum albumin, bovine (152-168)  0   *Peptide Fragments *Serum Albumin, Bovine Diabetes Mellitus, Type 1. N Engl J Med 1992 Jul 30;327(5):302-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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