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Diamines

More information in Books or onNLM PubMed
Definition: Organic chemicals which have two amino groups in an aliphatic chain.     
Examples Cadaverine; Ethylenediamines; Phenylenediamines; Putrescine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-(methylamino)-2-((methylamino)methyl)propane-1-thiol  0   *Diamines *Sulfhydryl Compounds. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7426-30.
3,4-diamino-1,2,4-triazole  0   *Diamines *Triazoles. J Phys Chem A. 2011 Aug 4;115(30):8550-62
N,N'-di-(4-decyloxysalicylidene)-1',6'-diaminohexane  0   *Diamines *Schiff Bases. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Sep;79(5):1654-9
N,N-dibenzyl-cyclohexane-1,2-diamine  0   *Cyclohexanes *Diamines. Eur J Med Chem. 2011 Feb;46(2):480-7
9'-epi-3beta,3'beta-dimethylxestospongin C  0   *Diamines *Macrocyclic Compounds Alkaloids. Planta Med. 2011 Jan;77(2):179-81
SGI-1252  0   *Diamines *Pyrimidines. Exp Hematol. 2011 Jan;39(1):14-25
1,4-trans-1,5-cis- 4,5-diamino-2-cyclopenten-1-ol  0   *Cyclopentanes *Diamines. J Org Chem. 2010 Sep 3;75(17):6012-5
pimaricin-inducing factor, Streptomyces natalensis  0   *Diamines. Org Lett. 2010 Aug 6;12(15):3522-4
4-(aminomethyl)-N,N'-diethylpyridazine-3,5-diamine  0   *Diamines *Pyridazines. Chem Pharm Bull (Tokyo). 2010;58(7):964-70
N,N,N',N'-tetramethylethanediamine  0   *Diamines. Mutat Res. 2010 Jul 19;700(1-2):26-31
N1,N2-bis(2,4,6-trihydroxy-3,5-diaminocyclohexyl)ethane-1,2-diamine  0   *Cyclohexanes *Diamines. Chemistry. 2010 Mar 15;16(11):3326-40
(E)-N-((6-chloro-4-(4-chlorophenyl)-3-methyl-1-phenyl-1H-pyrazolo(3,4-b)pyridin-5-yl)methylene)benzene-1,2-diamine  0   *Diamines *Pyridines. Acta Crystallogr C. 2010 Mar;66(Pt 3):o137-40
N1,N3-bis(4-amidinophenyl)propane-1,3-diamine  0   *Diamines Propane/*analogs & derivatives. Org Lett. 2010 Jan 15;12(2):216-9
N,N'-bis(6-methyl-2-pyridylmethylene)ethane-1,2-diamine  0   *Diamines *Pyridines. Chem Commun (Camb). 2009 Oct 28;(40):6098-100
N,N'-bis((E)-quinoxalin-2-ylmethylidene)butane-1,4-diamine  0   *Diamines *Quinoxalines. Acta Crystallogr C. 2009 Dec;65(Pt 12):o612-4
N,N'-bis((E)-quinoxalin-2-ylmethylidene)propane-1,3-diamine  0   *Diamines *Quinoxalines. Acta Crystallogr C. 2009 Dec;65(Pt 12):o612-4
5-nitro-N4,N6-diphenylpyrimidine-4,6-diamine  0   *Diamines *Pyrimidines. Acta Crystallogr C. 2009 Sep;65(Pt 9):o438-40
3-phenylpropane-1,2-diamine  0   *Diamines. Bioorg Med Chem. 2009 Apr 1;17(7):2775-84
N,N'-dimethylpropane-1,3-diamine  0   *Diamines. Eur J Mass Spectrom (Chichester, Eng) 2009;15(2):105-12
haliclonin A  0   *Diamines *Macrocyclic Compounds. Org Lett 2009 Apr 16;11(8):1713-6
REP8839  0   *Diamines *Thiophenes. Curr Opin Chem Biol 2008 Aug;12(4):409-17
N1-(2-(4-(dimethylamino)phenyl)benzothiazol-5-yl)butane-1,4-diamine  0   *Diamines *Benzothiazoles. Mol Biosyst. 2008 Jun;4(6):571-8
N,N,N',N'-tetramethylchloroformamidinium  0   *Diamines. Bioconjug Chem 2008 Oct;19(10):1968-71
N-(3-aminopropyl)-1,3-propanediamine  0   *Diamines Propane/*analogs & derivatives. Chemistry. 2008;14(3):909-18
(N,N'-bis((2-N-methylimidazol-1-yl)methylene))-2,2-dimethylpropane-1,3-diamine  0   *Diamines *Imidazoles. Chem Commun (Camb). 2007 Dec 28;(48):5223-5
N-diethylendiamine  0   *Diamines *Ethylenes. Spectrochim Acta A Mol Biomol Spectrosc. 2007 Nov;68(3):942-7
(6-chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo(2,3-b)pyridin-4-yl)oxy)-phenyl)pyrimidine-2,4-diamine)  0   *Diamines *Pyrimidines. Br J Pharmacol. 2007 Dec;152(7):1070-80
6-phenyl-1,3,5-triazine-2,4-diamine  0   *Diamines *Triazines. Acta Crystallogr C 2007 Aug;63(Pt 8):o474-6
N'-(10H-indolo(3,2-b)quinolin-11-yl)-N,N-dimethylpropane-1,3-diamine  0   *Diamines *Quinolines Telomerase/antagonists & inhibitors. Leukemia 2007 Jun;21(6):1300-2
N,N'-bis(salicylidene)-1.2-propanediamine  0   *Diamines *Schiff Bases. J Pharm Biomed Anal 2006 Mar 3;40(4):833-9
NSC 339585  0   *Anthracenes *Diamines. Proc Natl Acad Sci U S A 2006 Apr 18;103(16):6344-9
1,6-bis(N,N-dimethyl-2',6'-dimethyltyrosyl-1,2,3,4-tetrahydro-3-isoquinolineamido)hexane  0   *Diamines *Peptides Receptors, Opioid, mu/antagonists & inhibitors Receptors, Opioid, delta/antagonists & inhibitors. J Med Chem 2005 Dec 15;48(25):8035-44
N,N'-bis(3,5-di-tert-butylsalicylidene)-5,6-(1,10-phenanthroline)diamine  0   *Diamines *Phenanthrolines. Chemistry. 2005 Jun 6;11(12):3698-710
1,3-bis(N,N-dipropylamino)-2-O-sulfopropane  0   *Diamines *Sulfuric Acid Esters. Electrophoresis 2005 Jun;26(13):2503-10
1,3-bis(N,N-dimethylamino)-2-O-sulfopropane  0   *Diamines *Sulfuric Acid Esters. Electrophoresis 2005 Jun;26(13):2503-10
1,5-diamino-2-pentyne  0   *Alkynes *Diamines. Eur J Biochem 2004 Dec;271(23-24):4696-708
N-methyl-o-diaminobenzene  0   *Benzene Derivatives *Diamines. Inorg Chem. 2004 Oct 4;43(20):6445-54
1,1'-binaphthyl-2,2'-diamine  0   *Diamines *Naphthalenes. Inorg Chem. 2004 Oct 4;43(20):6168-76
N,N'-diformyl-N,N'-bis(1-methyl-2-S-thiobenzoyl-4-methoxybut-1-enyl)-1,2-diaminododecane  0   *Diamines. Clin Chem 2005 Mar;51(3):593-602
Olaflur  0 2,2'-(3-(N-(2-Hydroxyethyl)octadecylamino)propylimino)diethanol dihydrofluoride  *Diamines *Fluorides.
Pharma Action Cariostatic Agents 		Caries Res 2004 Nov-Dec;38(6):561-6
N,N'-bis(3-hydroxyphenyl)pyridazine-3,6-diamine  0   *Diamines *Pyridazines. Br J Pharmacol 2002 Nov;137(5):676-82
N,N'-bis(1-(4-methoxyphenyl-6-hydroxy-hex-2-ene-1-one-3-yl)-1,2-ethanediamine)  0   *Alkenes *Diamines. Bioorg Med Chem 2001 Dec;9(12):3093-9
N,N'-bis(1-(4-chlorophenyl-6-hydroxy-hex-2-ene-1-one-3-yl)-1,2-ethanediamine)  0   *Alkenes *Diamines. Bioorg Med Chem 2001 Dec;9(12):3093-9
poly-(Gd-DTPA)-co-(1,6-diaminohexane)  0   *Diamines Gadolinium DTPA/*analogs & derivatives. J Magn Reson Imaging 2001 Nov;14(5):608-16
6,6'-dithiobishexanamine  0   *Diamines *Disulfides. Bioelectrochemistry 2001 Mar;53(2):183-91
4,9-dioxa-1,12-dodecanediamine  0   *Alkanes *Diamines. J Magn Reson 2000 Dec;147(2):361-5
camphordiamine  0   *Diamines Camphor/*analogs & derivatives. J Org Chem 2000 Jul 28;65(15):4753-5
IEM 1925  0   *Quaternary Ammonium Compounds *Diamines. Br J Pharmacol 2000 Jan;129(2):265-74
Cholazol H  0   *Diamines Dietary Fiber. Metabolism 1998 Aug;47(8):959-64
3-(hydroxyamino)propylamine  0   *Diamines. Bioorg Med Chem 1997 Nov;5(11):2089-94
2-(naphthalen-1-yl)-3-phenylpropane-1,2-diamine  0   *Diamines *Naphthalenes Receptors, Neuropeptide Y/antagonists & inhibitors. Eur J Pharmacol 1997 Aug 27;333(2-3):R3-R5
N,N'-dimethyl-2-nitro-1,1-ethenediamine  0   *Diamines. J Pharm Biomed Anal 15(11):1667-78
ZM 240304  0   *Diamines *Phenyl Ethers. J Antimicrob Chemother 1996 Oct;38(4):605-14
TE 393  56-22-4   *Diamines. Brain Res 1995 May 8;679(1):15-24
CM 178-78  102974-82-3   *Diamines. Eur J Pharmacol 1994 Nov 14;265(1-2):93-8
glucoprotamine  0   *Diamines *Pyrrolidinones. Zentralbl Hyg Umweltmed 1994 Jun;357-65
N,N'-bis(3-(ethylamino)propyl)-1,8-octanediamine  122560-21-8   *Diamines. Anticancer Res 1994 Mar-Apr;14(2A):347-56
diaminomethane  2372-88-5   *Diamines. Int J Pept Protein Res 1993 Jul;42(1):53-7
N,N,N',N'-tetramethyl-1,7-heptanediamine  29333-99-1 1,7-Heptanediamine, N,N,N',N'-tetramethyl  *Diamines. Biol Cell 1993;77(2):195-9
3-(n-propylamino)propylamine  23764-31-0   *Diamines. Cancer Res 1993 Feb 1;53(3):564-8
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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