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Diazomethane

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Definition:       Other names Diazirine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2,6-diisopropyl-4-(3-(3-methyl-3H-diazirin-3-yl)propyl)phenol  0   Diazomethane/*analogs & derivatives Propofol/*analogs & derivatives. J Med Chem. 2011 Dec 8;54(23):8124-35.
ethyl 1-(1-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)ethyl)-1H-imidazole-5-carboxylate  0   Diazomethane/*analogs & derivatives Etomidate/*analogs & derivatives. J Med Chem 2010 Sep 9;53(17):6432-44
m-azipropofol  0   Diazomethane/*analogs & derivatives Propofol/*analogs & derivatives. J Med Chem 2010 Aug 12;53(15):5667-75
3-azibutanol  0   *Butanols Diazomethane/*analogs & derivatives. Proc Natl Acad Sci U S A 2008 Jan 8;105(1):371-5
4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate  0   Diazomethane/*analogs & derivatives Etomidate/*analogs & derivatives. J Med Chem 2006 Aug 10;49(16):4818-25
9H-fluoren-2-yldiazomethane  0   *Fluorenes Diazomethane/*analogs & derivatives. Biomacromolecules 2006 Jun;7(6):1743-50
N-((9-fluorenyl)methoxycarbonyl)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenylalanine  0   Diazomethane/*analogs & derivatives Phenylalanine/*analogs & derivatives. J Med Chem 2006 Apr 6;49(7):2200-9
dichlorodiazirine  0   Diazomethane/*analogs & derivatives. J Am Chem Soc. 2005 Oct 19;127(41):14206-7
9-(((2-iodo-4-((trifluoromethyl)-3H-diazirin-3-yl)benzyl)oxy)carbonyl)nonanoic acid  0   *Fatty Acids Diazomethane/*analogs & derivatives. Anal Biochem 2005 May 15;340(2):373-5
(2'-iodo-4'-(3''-trifluoromethyldiazirinyl)phenoxy)glucopyranoside  0   *Glucosides Diazomethane/*analogs & derivatives. Anal Biochem 2003 Dec 1;323(1):74-83
(trimethylsilyl)diazaomethane  0   *Trimethylsilyl Compounds Diazomethane/*analogs & derivatives. Org Lett 2002 Feb 21;4(4):489-92
carbobenoxy-phenylalanyl-serine(O-benzyl)diazomethane  0   *Dipeptides Diazomethane/*analogs & derivatives. Brain Res 2001 May 18;901(1-2):94-101
diazomethylarachidonyl ketone  0   *Arachidonic Acids Diazomethane/*analogs & derivatives. J Pharmacol Exp Ther 1998 Jul;286(1):184-90
dibenzoyldiazomethane  0   Diazomethane/*analogs & derivatives. Nucleic Acids Symp Ser 1997;(37):85-6
benzyloxycarbonylleucyl-leucyl-tyrosine diazomethyl ketone  0   *Oligopeptides Diazomethane/*analogs & derivatives. Exp Cell Res 1994 Nov;215(1):164-71
glycylphenylalanine diazomethyl ketone  0   *Dipeptides Diazomethane/*analogs & derivatives. J Biol Chem 1994 Oct 14;169(41):25897-904
4-(diazomethyl)-7-(diethylamino)coumarin  88861-43-2   *Coumarins Diazomethane/*analogs & derivatives Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors. J Biol Chem 1994 Mar 4;269(9):6892-9
diazo-4  123330-72-3   Diazomethane/*analogs & derivatives Egtazic Acid/*analogs & derivatives. J Physiol (Lond) 1993 May;464:501-28
biotin-phenylalanyl-(S-benzyl)cysteinyl-diazomethane  153512-31-3   *Oligopeptides Diazomethane/*analogs & derivatives. Parasitology 1993 Jun;106( Pt 5):487-93
farnesyl diazomethyl ketone  83053-30-9   Diazomethane/*analogs & derivatives Farnesol/*analogs & derivatives. Gen Comp Endocrinol 1990;80(2):232
biotin-phenylalanyl-alanine diazomethyl ketone  127678-91-5   Biotin/*analogs & derivatives Diazomethane/*analogs & derivatives Cathepsin B/antagonists & inhibitors. Biochem Soc Trans 1990;18(2):315
trimethylsilyldiazomethane  18107-18-1 Silane, (diazomethyl)trimethyl  *Trimethylsilyl Compounds Diazomethane/*analogs & derivatives. Yakugaku Zasshi 1988;108(12):1115
iodocyanopindolol diazirine  0   Diazomethane/*analogs & derivatives Iodocyanopindolol/*analogs & derivatives. Biochem Biophys Res Commun 1988;157(3):921
benzyloxycarbonyltyrosylalanine diazomethane  117176-50-8   *Dipeptides Diazomethane/*analogs & derivatives Cathepsin B/antagonists & inhibitors. Biochem J 1988;254(3):693
carbobenzoxyphenylalanylarginyldiazomethane  113823-66-8   *Dipeptides Diazomethane/*analogs & derivatives. Biochem J 1988;250(2):621
diazomethylgalactopyranosyl ketone  108672-06-6   Diazomethane/*analogs & derivatives Galactose/*analogs & derivatives. Carbohydr Res 1987;168(1):7
N-benzyloxycarbonylglycyl-proline diazomethyl ketone  101412-97-9   Diazomethane/*analogs & derivatives. Biochem Biophys Res Commun 1986;134(2):888
benzyloxycarbonylalanyl-alanyl-proline diazomethyl ketone  77180-12-2 Carbamic acid, (2-((2-(2-(diazoacetyl)-1-pyrrolidinyl)-1-methyl-2-oxoethyl)amino)-1-methyl-2-oxoethyl)-, phenylmethyl ester, (2S-(1(R*(R*)),2R*))  Diazomethane/*analogs & derivatives. Arch Biochem Biophys 1983;225(1):331
N-carbobenzoxypyroglutamyl diazomethyl ketone  81910-23-8 1-Pyrrolidinecarboxylic acid, 2-(diazoacetyl)-5-oxo-, phenylmethyl ester, (S)  Diazomethane/*analogs & derivatives Pyroglutamyl-Peptidase I/antagonists & inhibitors. Biochim Biophys Acta 1982;702(2):149
benzyloxycarbonylphenylalanylphenylalanine diazomethyl ketone  65178-14-5 Carbamic acid, (2-((3-diazo-2-oxo-1-(phenylmethyl)propyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, phenylmethyl ester, (S-(R*,R*))  Diazomethane/*analogs & derivatives. Biochem Biophys Res Commun 1981;101(2):454
benzyloxycarbonylphenylalanylalanine diazomethyl ketone  0   Diazomethane/*analogs & derivatives.
Pharma Action Cysteine Proteinase Inhibitors
Biochem J 1980;186(2):385
carbobenzoxycarbonyl-L-phenylalanyl-L-alanine-D-diazomethane  71732-53-1 Carbamic acid, (2-((3-diazo-1-methyl-2-oxopropyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, phenylmethyl ester, (S-(R*,R*))  Diazomethane/*analogs & derivatives. Fed Proc 39(1):15;1980
peptidyl diazomethyl ketones  0   *Ketones Diazomethane/*analogs & derivatives. Biochem Biophys Res Commun 89(4):1354;1979
N-benzyloxycarbonylphenylalanine diazomethyl ketone  15196-02-8 Carbamic acid, (3-diazo-2-oxo-1-(phenylmethyl)propyl)-, phenylmethyl ester, (S)  *Ketones Diazomethane/*analogs & derivatives. Biochemistry 16(26):5857;1977
diazomethyl ketones  0   Diazomethane/*analogs & derivatives. Biochem Biophys Res Commun 79(3):926;1977; Biochem J 175(2):761;1978; Biochemistry 16(26):5857;1977; J Med Chem 1980;23(3):275

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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