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Diclofenac

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Definition: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.     
Pharmacological Action Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors 		Other names Diclophenac; SR 38; GP45,840; GP 45,840; Diclofenac, Sodium; Voltarol; Voltaren; Sodium Diclofenac; SR-38; Ortofen; Orthophen; Orthofen; Novapirina; GP-45,840; Feloran; Dicrofenac; Diclonate P; Diclofenac Sodium; Diclofenac Potassium; DichlofenalDrugs* : PENNSAID; VOLTAREN; CATAFLAM; SOLARAZE; DICLOFENAC POTASSIUM; CAMBIA; VOLTAREN-XR; DICLOFENAC SODIUM; ZIPSOR
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pivoloxymethyl 2-((2,6-dichlorophenyl)amino)benzeneacetate  0   Diclofenac/*analogs & derivatives. J Med Chem 2011 Mar 10;54(5):1202-10
2-((2-(nitrooxy)ethyl)disulfanyl)ethyl 2-(2-(2,6-dichlorophenylamino)phenyl)acetate  0   *Nitrates Diclofenac/*analogs & derivatives. Inflammopharmacology 2010 Aug;18(4):157-68
2-(2,6-dichlorophenylamino)benzoic acid  0   Diclofenac/*analogs & derivatives. Drug Metab Lett 2008 Jan;2(1):35-40
HIFENAC MR  0   *Acetaminophen *Chlorzoxazone Diclofenac/*analogs & derivatives. J Chromatogr Sci 2008 Aug;46(7):649-52
2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester  0   *Thiones Diclofenac/*analogs & derivatives. Free Radic Biol Med 2007 Mar 1;42(5):706-19
ZLR-8 compound  0   Diclofenac/*analogs & derivatives. Biomed Chromatogr 2007 Apr;21(4):382-8
2-(3-chlorophenylamino)phenylacetic acid  0   Diclofenac/*analogs & derivatives. Kidney Int 2002 Jun;61(6):2025-32
ATB 337  0   *Heterocyclic Compounds, 1-Ring Diclofenac/*analogs & derivatives. Gastroenterology 2007 Jan;132(1):261-71
4'-hydroxy-2'-glutathion-deschloro-diclofenac  0   Diclofenac/*analogs & derivatives Glutathione/*analogs & derivatives. Drug Metab Dispos. 2005 Apr;33(4):484-8
diclofenac-S-acyl-glutathione  0   Diclofenac/*analogs & derivatives Glutathione/*analogs & derivatives. Chem Res Toxicol 2003 Nov;16(11):1410-7
1-O-(2-((2',6'-dichlorophenyl)amino)phenylacetyl)glucopyranuronic acid  0   *Glucuronides Diclofenac/*analogs & derivatives. J Med Chem 2004 May 20;47(11):2816-25
Neodolpasse  0   *Diclofenac *Orphenadrine Drug Combinations. Acta Chir Orthop Traumatol Cech. 2004;71(2):80-3
lumiracoxib  0 2-(2-((2-chloro-6-fluoro-phenyl)amino)-5-methyl-phenyl)acetic acid  Diclofenac/*analogs & derivatives.
Pharma Action Cyclooxygenase 2 Inhibitors 		Drugs 2003;63(1):33-45
Arthotec  0   *Diclofenac. N Engl J Med 2001 Dec 20;345(25):1856
manyana  0   *Benzophenones *Diclofenac *Piperidines Drug Combinations. J Indian Med Assoc 1998 Nov;96(11):359-60
5-hydroxydiclofenac  0   Diclofenac/*analogs & derivatives. Chem Res Toxicol 1999 Feb;12(2):214-22
4'-hydroxydiclofenac  0   Diclofenac/*analogs & derivatives. Eur J Pharmacol 1997 Jun 25;329(2-3):181-7
4'-hydroxyaceclofenac  0   Diclofenac/*analogs & derivatives. Eur J Pharmacol 1997 Jun 25;329(2-3):181-7
nitrofenac  154766-10-6 Nitrofenac  Diclofenac/*analogs & derivatives. Pharmacol Res 1994 Jan-Feb;29(1):89-97
Arthrotec  0   *Diclofenac.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal 		Scand J Rheumatol 1992;96:37-48ARTHROTEC
diclofenac hydroxyethylpyrrolidine  119623-66-4   Diclofenac/*analogs & derivatives.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal 		Eur J Clin Pharmacol 1990;38(2):207FLECTOR
3'-hydroxy-4'-methoxydiclofenac  106610-60-0   Diclofenac/*analogs & derivatives. Xenobiotica 1988;18(10):1191
aceclofenac  89796-99-6   Diclofenac/*analogs & derivatives.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal 		Farmaco (Prat) 1988;43(1):19
acetaminophen, caffeine, carisoprodol, diclofenac drug combination  0   *Acetaminophen *Caffeine *Carisoprodol *Diclofenac Drug Combinations. Br J Haematol 30(3):343;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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