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Dihydroergotamine

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Definition: A 9,10alpha-dihydro derivative of ERGOTAMINE. It is used as a vasoconstrictor, specifically for the therapy of MIGRAINE DISORDERS.     
Pharmacological Action Analgesics, Non-Narcotic; Dopamine Agonists; Vasoconstrictor Agents 		Other names Xcel Brand 1 of Dihydroergotamine Mesylate; Wernigeroide Brand of Dihydroergotamine Mesylate; Verladyn; Verla Brand of Dihydroergotamine Mesylate; Tamik; Shire Brand of Dihydroergotamine Mesylate; Seglor; Schwarz Brand of Dihydroergotamine Mesylate; Sanol Brand of Dihydroergotamine Mesylate; Q-Pharm Brand of Dihydroergotamine Mesylate; Pierre Fabre Brand of Dihydroergotamine Mesylate; Pharmafrid Brand of Dihydroergotamine Mesylate; Orstanorm; Novartis Brand of Dihydroergotamine Mesylate; Migranal; Ikaran; IPRAD Brand of Dihydroergotamine Mesylate; Hormosan Brand of Dihydroergotamine Mesylate; Fujisawa Brand of Dihydroergotamine Mesylate; Farmasan Brand of Dihydroergotamine MesylateDrugs* : MIGRANAL; D.H.E. 45; DIHYDROERGOTAMINE MESYLATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
8'-hydroxydihydroergotamine  90650-44-5 Ergotaman-3',6',18-trione, 9,10-dihydro-8',12'-dihydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha,10alpha)  Dihydroergotamine/*analogs & derivatives. Eur J Clin Pharmacol 1984;26(2):239
Dihydergot plus  81643-69-8 Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha,10alpha)-, monomethanesulfonate (salt), mixt. with (R)-alpha-((ethylmethylamino)methyl)-3-hydroxybenzenemethanol  *Dihydroergotamine *Etilefrine Drug Combinations. Ther Ggw 1982;121(1):26
heparin-dihydergot  0   *Dihydroergotamine *Heparin, Low-Molecular-Weight Drug Combinations. Med Welt 1981;32(25):1021EMBOLEX
Venelbin  76515-02-1 Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha,10alpha)-, monomethanesulfonate (salt), mixt. with 2-(3,4-bis(2-hydroxyethoxy)phenyl)-3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy  *Dihydroergotamine Drug Combinations Hydroxyethylrutoside/*analogs & derivatives. ZFA (Stuttgart) 1980;56(13):953
Silentan  79084-81-4 Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha,10alpha)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (2:1) (salt), mixt. with 2-(acetyloxy)benzoic acid, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2  *Aspirin *Caffeine *Diazepam *Dihydroergotamine Drug Combinations. MMW 121(10):355;1979
dihydroergotamine, dihydroergotoxine drug combination  0   *Dihydroergotamine *Dihydroergotoxine Drug Combinations. Fortschr Med 4(27):1502;1976; Fortschr Med 96(34):1735;1978
Ergo-Lonarid  77097-84-8 Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha,10alpha)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (2:1) (salt), mixt. with (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol phosphate (1:1)  *Acetaminophen *Amobarbital *Codeine *Dihydroergotamine Drug Combinations. Z Allgemeinmed 46(6):300;1970

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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