encyclopedia of medical concepts
ψ 
ψ 

Dihydroxydihydrobenzopyrenes

More information in Books or onNLM PubMed
Definition: Benzopyrenes saturated in any two adjacent positions and substituted with two hydroxyl groups in any position. The majority of these compounds have carcinogenic or mutagenic activity.  carcinogens; D25-26 qualif; DF: DDBPS   
Examples 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 		Other names Dihydrodiolbenzopyrenes; Dihydrobenzopyrene Diols; Benzopyrene Dihydrodiols; Diols, Dihydrobenzopyrene; Dihydrodiols, Benzopyrene
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
11beta,12alpha-dihydroxy-13alpha,14alpha-epoxy-11,12,13,14-tetrahydrodibenzo(a,l)pyrene  0   *Dihydroxydihydrobenzopyrenes. Chem Res Toxicol. 2008 Dec;21(12):2379-92
3-nitrobenzo(a)pyrene-trans-7,8-dihydrodiol  0   *Dihydroxydihydrobenzopyrenes. Cancer Lett 1999 Apr 1;137(2):136-43
1-nitrobenzo(a)pyrene-trans-7,8-dihydrodiol  0   *Dihydroxydihydrobenzopyrenes. Cancer Lett 1999 Apr 1;137(2):137-43
dibenzo(a,l)pyrene 11,12-dihydrodiol  88191-01-9   *Dihydroxydihydrobenzopyrenes. Carcingoenesis 1991;12(10):1939
dibenzo(a,l)pyrene 8,9-dihydrodiol  130063-43-3   *Dihydroxydihydrobenzopyrenes. Carcinogenesis 1991;12(10):1939
3-hydroxy-7,8-dihydro-7,8-dihydroxybenzo(a)pyrene  99346-47-1   *Dihydroxydihydrobenzopyrenes. Carcinogenesis 1985;6(10):1507
11,12-dihydro-11,12-dihydroxybenzo(a)pyrene  28622-86-8   *Dihydroxydihydrobenzopyrenes. Biochem Biophys Res Commun 1985;130(1):71
9-methoxy-4,5-dihydroxy-4,5-dihydrobenzo(a)pyrene  87771-55-9 Benzo(a)pyrene-4,5-diol, 4,5-dihydro-9-methoxy-, trans  *Dihydroxydihydrobenzopyrenes. Science 1984;223(4633):289
7,8-dihydroxy-7,8-dihydro-8-methylbenzo(a)pyrene  89524-80-1 Benzo(a)pyrene-7,8-diol, 7,8-dihydro-8-methyl-, trans  *Dihydroxydihydrobenzopyrenes. Carcinogenesis 1983;4(10):1297
3,4-dihydro-3,4-dihydroxybenzo(a,i)pyrene  80155-83-5 Benzo(rst)pentaphene-3,4-diol, 3,4-dihydro  *Dihydroxydihydrobenzopyrenes. Cancer Res 1981;41(7):2589
1,2-dihydro-1,2-dihydroxydibenzo(a)pyrene  80155-85-7 Dibenzo(b,def)chrysene-1,2-diol, 1,2-dihydro  *Dihydroxydihydrobenzopyrenes. Cancer Res 1981;41(7):2589
9,10-dihydroxy-9,10-dihydrobenzo(e)pyrene  88190-97-0   *Dihydroxydihydrobenzopyrenes. Cancer Res 40(2):203;1980
4,5-dihydroxy-4,5-dihydrobenzo(e)pyrene  24961-49-7   *Dihydroxydihydrobenzopyrenes. Cancer Res 40(2):203;1980
9,10-dihydro-9,10-dihydroxybenzo(a)pyrene  24909-09-9   *Dihydroxydihydrobenzopyrenes. Chem Biol Interact 26(2):147;1979
benzo(a)pyrene 7,8-dihydrodiol  13345-25-0   *Dihydroxydihydrobenzopyrenes. Arch Biochem Biophys 183(1):31;1977; Biochem Biophys Res Commun 82(1):210;1978; Biochem Biophys Res Commun 85(4):1535;1978; Biochem Pharmacol 1980;29(4):495; Br J Cancer 37(5):657;1978; Cancer Res 1979;39(10):4123; Cancer Res 1980;40(2):207; Cancer Res 1980;40(4):1281; Cancer Res 38(9):2661;1978; Cancer Res 38:1241;1978; FEBS Lett 1979;106(1):13; FEBS Lett 1979;106(1):17; J Clin Invest 1979;64(5):1245; JNCI 1980;64(3):617; JNCI 62(4):1103;1979; Mutat Res 58(2-3):361;1978
4,5-dihydroxy-4,5-dihydrobenzo(a)pyrene  28622-84-6   *Dihydroxydihydrobenzopyrenes. Biochem Soc Transact 5(5):1368;1977; Cancer Res 1980;40(1):101

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy