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p-Dimethylaminoazobenzene

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Definition: A reagent used mainly to induce experimental liver cancer. According to the Fourth Annual Report on Carcinogens (NTP 85-002, p. 89) published in 1985, this compound "may reasonably be anticipated to be a carcinogen." (Merck, 11th ed)  usually NIM in DAB-induced exper cancer: no qualif; when IM, D25-26 qualif; DF: note short X ref   
Pharmacological Action Carcinogens; Coloring Agents
Examples Methyldimethylaminoazobenzene 		Other names Dimethylaminoazobenzene; Butter Yellow; p Dimethylaminoazobenzene; p-Dimethylaminoazobenzene, (Z)-Isomer; p-Dimethylaminoazobenzene, (E)-Isomer; 4 Dimethylaminoazobenzene; Methyl Yellow; 4-Dimethylaminoazobenzene
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
octyl-dimethylaminobenzoate  0   p-Dimethylaminoazobenzene/*analogs & derivatives. Pharmazie. 2006 Jan;61(1):41-5
MB-P3 molecular beacon  0   *Oligodeoxyribonucleotides p-Dimethylaminoazobenzene/*analogs & derivatives. Nucleic Acids Res 2005;33(18):5763-70
methyl-red (2-(4-dimethylamino-phenylazo)-benzoic acid)  0   p-Dimethylaminoazobenzene/*analogs & derivatives. Water Sci Technol 2004;49(4):183-8
5-p-dimethyl-aminophenylazobenzthiazole  0   *Thiazoles p-Dimethylaminoazobenzene/analogs & derivatives. Environ Mol Mutagen 1999 ;34(2-3):148-53
4-(4-dimethylaminophenylazo)benzoic acid  6268-49-1   p-Dimethylaminoazobenzene/*analogs & derivatives. Science 1990;247(4945):954
N,N-dimethyl-4-aminoazobenzene N-oxide  2747-31-1   p-Dimethylaminoazobenzene/*analogs & derivatives. J Biochem Toxicol 1986;1(1):15
1-methyl-5-(4-dimethylaminophenylazo)indazole  122168-69-8   p-Dimethylaminoazobenzene/*analogs & derivatives. Mutagenesis 1986;1(4):261
4-(N,N)-dimethylaminoazobenzene-4'-sulfonyl hydrazine  72565-41-4   p-Dimethylaminoazobenzene/*analogs & derivatives. Anal Chem 1987;59(9):1320
4-dimethylaminophenylazophenyl-4'-maleimide  87963-80-2   p-Dimethylaminoazobenzene/*analogs & derivatives. Biochim Biophys Acta 1986;872(1-2):76
dimethylaminoazobenzene-4-sulfinate  131483-42-6   p-Dimethylaminoazobenzene/*analogs & derivatives. Anal Biochem 1985;149(1):66
4'-hydroxydimethylaminoazobenzene  2496-15-3   p-Dimethylaminoazobenzene/*analogs & derivatives. Hepatology 1986;6(1):123
N-benzoyloxy-3'-methyl-4-methylaminoazobenzene  67371-65-7   p-Dimethylaminoazobenzene/*analogs & derivatives. JNCI 1986;76(1):95
dimethylaminoazobenzene-4-thiosulfonate  98211-68-8   p-Dimethylaminoazobenzene/*analogs & derivatives. Anal Biochem 1985;149(1):66
2-(2-benzothiazolylazo)-5-dimethylaminobenzoic acid  83688-78-2 Benzoic acid, 2-(2-benzothiazolylazo)-5-(dimethylamino)  *Benzothiazoles p-Dimethylaminoazobenzene/*analogs & derivatives. Analyst 1985;110(4):399
4'-N,N-dimethylamino-4-aminoazobenzene  539-17-3   p-Dimethylaminoazobenzene/*analogs & derivatives. Anal Biochem 1985;147(1):156
4-dimethylaminoazobenzene-4'-N-maleimide  0 1H-Pyrrole-2,5-dione, 1-(4-((4-(dimethylamino)phenyl)azo)phenyl)  p-Dimethylaminoazobenzene/*analogs & derivatives. Biochem J 1983;211(1):163
4-dimethylaminoazobenzene-4'-iodoacetamide  77145-08-5 Acetamide, N-(4-((4-(dimethylamino)phenyl)azo)phenyl)-2-iodo  p-Dimethylaminoazobenzene/*analogs & derivatives. Biochem J 1983;211(1):163
5-dimethylaminophenylazoindazole  17309-86-3   p-Dimethylaminoazobenzene/*analogs & derivatives. Mutat Res 1983;116(3-4):271
4'-sulfonyloxy-N-(glutathion-S-methylene)-4-aminoazobenzene  85473-31-0 Glycine, N-(N-L-gamma-glutamyl-S-(((4-((4-(sulfooxy)phenyl)azo)phenyl)amino)methyl)-L-cysteinyl)  p-Dimethylaminoazobenzene/*analogs & derivatives. Chem Biol Interact 1983;43(2):123
3'-methyl-4-methylaminoazobenzene  2058-62-0   p-Dimethylaminoazobenzene/*analogs & derivatives. Biochem Biophys Res Commun 1982;106(1):164
3'-hydroxymethyl-4-dimethylaminoazobenzenecarbinol  0   p-Dimethylaminoazobenzene/*analogs & derivatives. Radioisotopes 1979;28(9):572
DABTH  72683-57-9 4-Imidazolidinone, 3-(4-((4-(dimethylamino)phenyl)azo)phenyl)-2-thioxo  *Thiohydantoins p-Dimethylaminoazobenzene/*analogs & derivatives. FEBS Lett 108(1):87;1979
4-(N,N-dimethylaminoazobenzene)-4'-isothiocyanate  7612-98-8   *Isothiocyanates p-Dimethylaminoazobenzene/*analogs & derivatives.
Pharma Action Indicators and Reagents 		Biochem J 153(3):607;1976; Biochem J 163:517;1977; Biochim Biophys Acta 578(1):175;1979; Biochim Biophys Acta 578(1):188;1979; FEBS Lett 1979;108(1):87; FEBS Lett 1979;108(1):92; J Chromatogr 135(1):245;1977
N,N-dimethyl-4-(6-benzothiazolylazo)aniline  18463-85-9 4-(6-benzothiazolylazo)-N,N-dimethylbenzenamine  *Benzothiazoles p-Dimethylaminoazobenzene/*analogs & derivatives. Bull Cancer 63(1):87;1976; C R Acad Sci [D] (Paris) 282(12):1219;1976
4-N,N-dimethylaminoazobenzene-4'-sulfonyl chloride  56512-49-3 Benzenesulfonyl chloride, 4-((4-(dimethylamino)phenyl)azo)  p-Dimethylaminoazobenzene/*analogs & derivatives.
Pharma Action Indicators and Reagents 		Analyt Chem 47(9):1634;1975; J Chromatogr 116(1):215;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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