Dinitrochlorobenzene (definition)

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Dinitrochlorobenzene

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Definition: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.

D25-26 qualif; DF: note short X ref
Pharmacological Action Indicators and Reagents; Irritants

Other names DNCB; Chlorodinitrobenzene; 1 Chloro 2,4 Dinitrobenzene; 1-Chloro-2,4-Dinitrobenzene

Substance	CAS Registry & name	Categories	Source
1-chloro-2,4-dinitrobenzene-glutathione conjugate	0	Dinitrochlorobenzene Glutathione Biological Transport, Active.	Br J Haematol 1984;58(1):200
4-chloro-3,5-dinitrophenylmethyl sulfone	4726-15-2	Dinitrochlorobenzene/*analogs & derivatives.	Arch Dermatol 1983;119(4):304
3,5-dinitro-4-chloro-alpha,alpha,alpha-trifluorotoluene	393-75-9	Dinitrochlorobenzene/*analogs & derivatives Tubulin Modulators.	Biochem Pharmacol 1980;29(18):2485
2-carboxy-4,6-dinitrochlorobenzene	2497-91-8	Dinitrochlorobenzene/*analogs & derivatives.	Int J Pept Protein Res 114(3):199;1979
fluorodinitrochlorobenzene	0	Dinitrochlorobenzene/*analogs & derivatives.	Exptl Cell Res 112:395;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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