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Dipeptides
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Definition
: Peptides composed of two amino acid units.
Examples
Anserine
;
Aspartame
;
Carnosine
;
Enalapril
;
Glycylglycine
;
Lisinopril
Substance
CAS Registry & name
Categories
Source
Drugs
*
UK101-
B660
0
*Boron Compounds
*Dipeptides.
Bioorg Med Chem. 2012 Jan 15;20(2):607-13.
UK101-
Fluor
0
*Dipeptides
*Fluoresceins.
Bioorg Med Chem. 2012 Jan 15;20(2):607-13.
2,6-
bis-
trifluoromethylbenzoic acid 2-
(1-
(ethoxycarbonylmethylcarbamoyl)-
3-
methylbutylcarbamoyl)allyl ester
0
*Dipeptides
*Methacrylates.
J Med Chem. 2012 Jan 12;55(1):55-67.
N-
(N-
(3-
(3-
hydroxy-
4-
methoxyphenyl) propyl)-
alpha-
aspartyl)-
L-
phenylalanine 1-
methyl ester
0
*Dipeptides
Sweetening Agents.
Food Chem Toxicol. 2011 Nov;49 Suppl 1():S8-29
cyclo(glycyltryptophyl)
0
*Dipeptides
*Peptides, Cyclic.
J Nat Prod. 2011 Oct 28;74(10):2278-81
2-
methylalanyl-
N-
(1-
(1-
(4-
fluorophenyl)-
1-
methyl-
2-
oxo-
2-
pyrrolidin-
1-
ylethyl)-
1H-
imidazol-
4-
yl)-
5-
phenylnorvalinamide
0
*Dipeptides
*Imidazoles.
Drug Metab Dispos. 2011 May;39(5):740-9.
2-
amino-
N-
(1-
(2-
amino-
3-
(4-
aminophenyl)-
3-
hydroxypropylamino)-
1-
oxo-
3-
phenylpropan-
2-
yl)-
4-
methylpentanamide
0
*Dipeptides
*Propanolamines
Antigens, CD13/antagonists & inhibitors.
Bioorg Med Chem. 2011 Sep 1;19(17):5190-8.
guanidiniocarbonyl pyrrole carboxylate-
phenylalanyl-
phenylalanine
0
*Dipeptides.
Chem Commun (Camb). 2011 Jul 28;47(28):7953-5
tyrosyl-
argininamide
0
*Dipeptides.
Br J Pharmacol 2011 Jul;163(5):964-73
N-
(tert-
butoxycarbonyl)-
L-
valyl-
L-
valine methyl ester
0
*Dipeptides.
Acta Crystallogr C. 2011 Aug;67(Pt 8):o278-82
N,N'-
((1,1'-
(oxybis(pentane-
5,1-
diyl))bis(1H-
1,2,3-
triazole-
4,1-
diyl))bis(phenylmethylene))bis(6-
(2-
(methylamino)propanamido)-
5-
oxodecahydropyrrolo(1,2-
a)azocine-
3-
carboxamide)
0
*Azocines
*Dipeptides.
J Med Chem 2011 May 12;54(9):3306-18
glycyl-
prolyl-
diphenylphosphonic acid
0
*Dipeptides
*Phosphonic Acids
Dipeptidyl Peptidase 4.
Arch Dermatol Res 2010 Dec;302(10):725-31
5-
hydroxysaxagliptin
0
*Dipeptides
Adamantane/*analogs & derivatives.
Clin Pharmacokinet. 2011 Apr 1;50(4):253-65
poly(lactic-
co-
glycolic acid)-
block-
poly(ethylene glycol)-
N-
(N-
(1,3-
dicarboxypropyl)carbamoyl)lysine
0
*Dipeptides
*Polyesters
Drug Delivery Systems.
J Med Chem 2011 Mar 10;54(5):1321-32
7-
butyl-
10-
amino-
camptothecin-
beta-
alanine-
lysine
0
*Dipeptides
Camptothecin/*analogs & derivatives
DNA Topoisomerases, Type I.
Cancer Chemother Pharmacol 2011 Apr;67(4):855-65
N-
valproyl-
L-
tryptophan
0
*Dipeptides.
Med Chem. 2011 Jan;7(1):9-17
TP 300
0
*Dipeptides
*Heterocyclic Compounds with 4 or More Rings.
Cancer Chemother Pharmacol 2010 Jan;65(2):363-71
S-
benzoylmercaptoacetylglycylglycyl
0
*Dipeptides.
Bioconjug Chem 2009 Aug 19;20(8):1559-68
ibodutant
0
*Dipeptides
*Thiophenes
Receptors, Neurokinin-2/antagonists & inhibitors.
Neurogastroenterol Motil 2011 Jan;23(1):96-102,e10
beta-
alanyl-
N-
propylhistidinamide
0
*Dipeptides.
J Med Chem 2011 Jan 27;54(2):611-21
N(epsilon)-
homocysteinyl-
lysine
0
*Dipeptides.
Amino Acids 2010 Nov;39(5):1563-9
Gly-
Pro-
BCD-
Tb
0
*Dipeptides
*Metalloproteins
Terbium.
Chemistry. 2010 Dec 3;16(45):13479-86
3-
(formylhydroxyamino)-
2-
(3-
phenyl-
1-
propyl)butanoic acid (2,2-
dimethyl-
1-
methylcarbamoyl-
1-
propyl)amide
0
*Dipeptides
*Hydroxamic Acids
ADAM Proteins/antagonists & inhibitors.
Blood 2003 Aug 15;102(4):1186-95
azonazine
0
*Dipeptides.
Org Lett. 2010 Oct 15;12(20):4458-61
UK 101
0
*Dipeptides
*Organosilicon Compounds.
J Phys Chem B 2010 Sep 30;114(38):12333-9
N6-
(2-
propargylglycyl)lysine
0
*Dipeptides.
Chem Asian J 2010 Aug 2;5(8):1765-9
5-
isoxazoyl-
cyclohexylalanyl-
isoleucyl-
spiroindane-
1,4'-
piperidine
0
*Dipeptides
*Isoxazoles
Receptor, PAR-2/antagonists & inhibitors.
J Med Chem 2010 Oct 28;53(20):7428-40
alpha-
aminoisobutyric acid-
D-
proline
0
*Dipeptides.
Org Biomol Chem. 2010 Jul 21;8(14):3133-5
3-
(benzyloxycarbonylleucylamino)-
N-
(3-
(6-
amino-
9H-
purin-
9-
yl)propyl)-
2-
oxopentanamide
0
*Dipeptides
Adenine/*analogs & derivatives
Calpain/antagonists & inhibitors.
J Med Chem 2010 Sep 9;53(17):6326-36
3-
(benzyloxycarbonylleucylamino)-
N-
(3-
(4-
methylpiperazin-
1-
yl)propyl)-
2-
oxopentanamide
0
*Dipeptides
*Piperazines
Calpain/antagonists & inhibitors.
J Med Chem 2008 Sep 11;51(17):5264-70
(9H-
fluoren-
9-
yl)methyl(1-
((6-
(tert-
butoxycarbonyl)amino-
1-
((4-
methyl-
2-
oxo-
1,2-
dihydroquinolin-
7-
yl)amino)-
1-
oxohexan-
2-
yl)amino)-
3-
cyclohexyl-
1-
oxopropan-
2-
yl)carbamate
0
*Dipeptides
*Quinolones.
Proc Natl Acad Sci U S A 2010 Aug 24;107(34):15229-34
narlaprevir
0
*Dipeptides
*Sulfones.
Antimicrob Agents Chemother 2010 Jun;54(6):2365-70
benzylsulfonylcyclohexylalanyl-
proline-
(4-
amidinobenzyl)amide
0
*Dipeptides
*Sulfonamides.
J Med Chem 2010 Aug 12;53(15):5523-35
benzylsulfonylargininyl-
proline-
(4-
amidinobenzyl)amide
0
*Dipeptides
*Sulfonamides.
J Med Chem 2010 Aug 12;53(15):5523-35
l-
phenylalanyl sarcosine
0
*Dipeptides.
Eur J Pharm Sci. 2010 Jun 14;40(3):202-8
4-
(4-
methoxyphenyl)-