Definition: A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair. EC 22.214.171.124.
Other names Pol I; Klenow Fragment; DNA-Dependent DNA Polymerase I; DNA Polymerase alpha; Polymerase alpha, DNA; Polymerase I, DNA; DNA Dependent DNA Polymerase I