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Dopamine beta-Hydroxylase

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Definition:       Other names beta-Monooxygenase, Dopamine; beta-Hydroxylase, Dopamine; Dopamine beta Monooxygenase; Dopamine beta Hydroxylase; Dopamine beta-Monooxygenase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Dopamine beta hydroxylase deficiency  0   *Autonomic Nervous System Diseases Dopamine beta-Hydroxylase/deficiency Norepinephrine/deficiency.
5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-2-thione  0   *Benzopyrans *Imidazoles Dopamine beta-Hydroxylase/antagonists & inhibitors. J Med Chem 2006 Feb 9;49(3):1191-7
nepicastat  0   *Imidazoles *Thiones Dopamine beta-Hydroxylase/antagonists & inhibitors. Br J Pharmacol 1997 Aug;121(8):1803-9
1-(4'-hydroxyphenyl)-1-(aminomethyl)ethene  0   *Phenols *Styrenes Dopamine beta-Hydroxylase/antagonists & inhibitors. Biochem Biophys Res Commun 1996 Nov 12;228(2):246-51
1-(4-hydroxybenzyl)pyrazole  80200-09-5 Phenol, 4-(1H-pyrazol-1-ylmethyl)  *Pyrazoles Dopamine beta-Hydroxylase/antagonists & inhibitors. Biochem J 1987;242(1):227
1-(3,5-difluorobenzyl)imidazole-2-thiol  0   *Imidazoles Dopamine beta-Hydroxylase/antagonists & inhibitors. J Pharmacol Exp Ther 1987;241(2):554
1-(4-hydroxybenzyl)imidazole-2-thiol  95333-64-5   *Imidazoles Dopamine beta-Hydroxylase/antagonists & inhibitors. Biochemistry 1986;25(23):7271
1-phenyl-1-propyne  673-32-5   *Alkynes Dopamine beta-Hydroxylase/antagonists & inhibitors. J Biol Chem 1984;259(24):15017
2'-chlorophenethylamine  4633-92-5 Benzeneethanamine, beta-chloro-, (11beta,16alpha)  *Phenethylamines Dopamine beta-Hydroxylase/antagonists & inhibitors. J Biol Chem 1984;259(12):7772
3-(4-hydroxyphenyl)-1-propane  3690-05-9   *Phenols Dopamine beta-Hydroxylase/antagonists & inhibitors. J Biol Chem 1984;259(11):6925
2-chloro-3-(4-hydroxyphenyl)-1-propene  13283-34-6 Phenol, 4-(2-chloro-2-propenyl)-, (3R-(3alpha,3aalpha,4beta,4abeta,7abeta,8alpha,9abeta))  *Phenols Dopamine beta-Hydroxylase/antagonists & inhibitors. J Biol Chem 1984;259(11):6925
2-bromo-(4-hydroxyphenyl)-1-propene  0   *Phenols Dopamine beta-Hydroxylase/antagonists & inhibitors. J Biol Chem 1984;259(6):3395
N,N-dimethyl-N'-1H-1,2,4-triazol-3-yl-thiourea  72601-96-8   *Triazoles Dopamine beta-Hydroxylase/antagonists & inhibitors. Life Sci 1984;34(5):447
1-phenyl-1-aminomethylethene  28144-67-4 Benzeneethanamine, beta-methylene  *Phenethylamines Dopamine beta-Hydroxylase/antagonists & inhibitors. Biochem Biophys Res Commun 1983;110(1):161
4-hydroxybenzylcyanide  14191-95-8 Benzeneacetonitrile, 4-hydroxy  *Acetonitriles Dopamine beta-Hydroxylase/antagonists & inhibitors. J Biol Chem 1980;255(19):8987
4-methyl-1-homopiperazinedithiocarboxylic acid  26865-04-3 hexahydro-4-methyl-1H-1,4-diazepine-1-carbodithioic acid  *Azepines Dopamine beta-Hydroxylase/antagonists & inhibitors. Arch Int Pharmacodyn Ther 230(1):65;1977; Arch Int Pharmacodyn Ther 232:102;1978; Pharmacol Biochem Behav 1979;11(5):545; Pharmacol Biochem Behav 9(5):603;1978
A32390A  61241-59-6 1,6-di-0-(2-isocyano-3-methylcrotonyl)-D-mannitol  Mannitol/*analogs & derivatives Dopamine beta-Hydroxylase/antagonists & inhibitors. Adv Enzym Regul 15:267;1977; J Antibiot 31(1):19;1978; J Antibiot 31(1):27;1978; J Antibiot 31(1):33;1978
BRL 8242  41926-69-6 1H-benzimidazol-2-amine, N-(4,5-dihydro-1H-imidazol-2-yl)-, dihydrochloride  *Benzimidazoles Dopamine beta-Hydroxylase/antagonists & inhibitors. Eur J Pharmacol 37(1):179;1976
5-(4'-chlorobutyl)picolinic acid  41135-83-5 5-(4-chlorobutyl)-2-pyridinecarboxylic acid  Fusaric Acid/*analogs & derivatives Dopamine beta-Hydroxylase/antagonists & inhibitors. Arzneim Forsch 25(1):55;1975; Arzneim Forsch 25(2):213;1975; Arzneim Forsch 25(3):383;1975; Chem Pharm Bull (Tokyo) 26(8):2328;1978
echinochrome A  517-82-8 2-ethyl- 2,5,6,7,8-pentahydroxy-1,4-naphthoquinone  *Naphthoquinones Dopamine beta-Hydroxylase/antagonists & inhibitors Pigments, Biological.
5-dimethyldithiocarbamylpicolinic acid  53562-97-3 5-(((dimethylamino)thioxomethyl)thio)-2-pyridinecarboxylic acid  *Picolinic Acids Dopamine beta-Hydroxylase/antagonists & inhibitors. J Pharmacol Exp Ther 191(3):384;1974; Jpn J Pharmacol 1979;29(2):187
dopastin  37134-80-8 N-(2-(hydroxynitrosoamino))-3-methylbutyl-2  *Amides Dopamine beta-Hydroxylase/antagonists & inhibitors. J Antibiotics 25(8):497;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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