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Drug Resistance, Microbial

More information in Books or onNLM PubMed
Definition: The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).  general or unspecified; prefer specifics; not for protozoa: index DRUG RESISTANCE   
See Also Microbial Sensitivity Tests; R Factors; Superinfection; Tuberculosis, Multidrug-Resistant
Examples Drug Resistance, Bacterial; Drug Resistance, Fungal; Drug Resistance, Viral 		Other names Antibiotic Resistance, Microbial; Antibiotic Resistance; Resistance, Antibiotic; Drug Resistances, Microbial; Antimicrobial Drug Resistances; Antimicrobial Drug Resistance
 
SubstanceCAS Registry & nameCategoriesSource
ermB protein, Streptococcus pyogenes  0   *Bacterial Proteins Drug Resistance, Microbial. Bull Soc Pathol Exot. 2010 May;103(2):69-74
EmrB protein, E coli  0   *Membrane Proteins *Escherichia coli Proteins Drug Resistance, Microbial. Biochem Biophys Res Commun 2009 Mar 6;380(2):338-42
beta-lactamase SHV-57, E coli  EC 3.5.2.6   *beta-Lactamases *Escherichia coli Proteins Drug Resistance, Microbial. Antimicrob Agents Chemother 2005 Feb;49(2):600-5
folate transporter 1, Leishmania infantum  0   *Anion Transport Proteins Drug Resistance, Microbial. J Biol Chem 2004 Dec 24;279(52):54494-501
VceA protein, Vibrio cholerae  0   *Bacterial Proteins *Membrane Proteins Drug Resistance, Microbial.
EmrA protein, E coli  0   *Membrane Proteins *Escherichia coli Proteins Drug Resistance, Microbial.
beta-lactamase CTX-M-32, E coli  EC 3.5.2.6   *beta-Lactamases Drug Resistance, Microbial. Antimicrob Agents Chemother 2004 Jun;48(6):2308-13
EmeA protein, Enterococcus faecalis  0   *Bacterial Proteins *Membrane Transport Proteins Drug Resistance, Microbial. Antimicrob Agents Chemother 2001 Dec;45(12):3574-9
MfpA protein, Mycobacterium smegmatis  0   *Bacterial Proteins *Drug Resistance, Microbial. Antimicrob Agents Chemother 2001 Dec;45(12):3387-92
AdeB protein, Acinetobacter baumannii  0   *Bacterial Proteins *Membrane Transport Proteins Drug Resistance, Microbial. Antimicrob Agents Chemother 2001 Dec;45(12):3375-80
ErmF protein, Bacteroides  EC 2.1.1.48   *Bacterial Proteins *Drug Resistance, Microbial *Methyltransferases. Appl Environ Microbiol 2001 Aug;67(8):3488-95
Mdt-A protein, E coli  0   *Drug Resistance, Microbial *Membrane Transport Proteins *Escherichia coli Proteins. Antimicrob Agents Chemother 2001 Apr;45(4):1109-14
ErmA protein, Bacteria  EC 2.1.1.48   *Bacterial Proteins *Methyltransferases Drug Resistance, Microbial. J Bacteriol 1985 May;162(2):633-40
Rcp protein, Legionella pneumophila  0   *Bacterial Proteins *Drug Resistance, Microbial. Infect Immun 2001 Jul;69(7):4276-86
Ant(4')-Ia protein, Staphylococcus aureus  EC 2.7.7.-   *Bacterial Proteins *Nucleotidyltransferases Drug Resistance, Microbial. J Antimicrob Chemother 1999 Feb;43(2):253-9
VanG protein, Enterococcus faecalis  0   *Bacterial Proteins *Drug Resistance, Microbial. Antimicrob Agents Chemother 2000 Nov;44(11):3224-8
CFR protein, Staphylococcus sciuri  0   *Bacterial Proteins *Drug Resistance, Microbial. Antimicrob Agents Chemother. 2000 Sep;44(9):2530-3
AADA7 protein, E coli  0   *Drug Resistance, Microbial *Escherichia coli Proteins. Antimicrob Agents Chemother 2000 Jun;44(6):1568-74
PmrB protein, bacteria  0   *Bacterial Proteins *Transcription Factors Drug Resistance, Microbial. J Bacteriol 1993 Jul;175(13):4154-64
AADA4 protein, E coli  0   *Drug Resistance, Microbial *Escherichia coli Proteins. Antimicrob Agents Chemother 2000 Feb;44(2):355-61
PdcA protein, Myxococcus xanthus  EC 3.4.-   *Bacterial Proteins *Carboxypeptidases Drug Resistance, Microbial. J Bacteriol 1999 Aug;181(15):4696-9
TlrB protein, Streptomyces fradiae  EC 2.1.1.-   *Methyltransferases Drug Resistance, Microbial. J Antibiot (Tokyo) 1999 Mar;52(3):288-96
varS protein, Streptomyces virginiae  0   *Bacterial Proteins *Membrane Proteins Drug Resistance, Microbial. J Bacteriol 1999 May;181(10):3293-7
Cmr protein, E coli  0   *Membrane Transport Proteins *Escherichia coli Proteins Drug Resistance, Microbial. EMBO J 1999 Feb 15;18(4):822-32
VanY protein, Bacteria  EC 3.4.16.4   *Bacterial Proteins *Carboxypeptidases *Membrane Proteins Drug Resistance, Microbial. Mol Microbiol 1998 Nov;30(4):819-30
MefA protein, Streptococcus  0   *Bacterial Proteins *Membrane Proteins Drug Resistance, Microbial. Mol Microbiol 1996 Dec;22(6):867-79
MerG protein, Pseudomonas  0   *Bacterial Proteins Drug Resistance, Microbial. J Bacteriol 1999 Feb;181(3):726-30
Tap protein, Mycobacterium  0   *Bacterial Proteins *Membrane Transport Proteins Drug Resistance, Microbial Drug Resistance, Multiple. J Bacteriol 1998 Nov;180(22):5836-43
Kmr protein, Streptomyces kanamyceticus  0   *Bacterial Proteins *Drug Resistance, Microbial. J Basic Microbiol 1998;38(4):231-9
OrfSbV protein, Leishmania tarentolae  0   *Protozoan Proteins Drug Resistance, Microbial. Antimicrob Agents Chemother 1998 Jul;42(7):1689-94
AlbA protein, Klebsiella oxytoca  0   *Bacterial Proteins *Carrier Proteins Drug Resistance, Microbial. Mol Microbiol 1988 Jul;2(4):443-54
ErmTR protein, bacteria  EC 2.1.1.-   *Bacterial Proteins *Methyltransferases Drug Resistance, Microbial. Antimicrob Agents Chemother 1998 Feb;42(2):257-62
LytH protein, Staphylococcus aureus  EC 3.5.1.28   *Bacterial Proteins *N-Acetylmuramoyl-L-alanine Amidase Drug Resistance, Microbial. J Bacteriol 1997 Oct;179(20):6294-301
VanC protein, Enterococcus  EC 6.3.2.-   *Bacterial Proteins *Peptide Synthases Drug Resistance, Microbial. Proc Natl Acad Sci U S A 1997 Sep 16;94(19):10040-4
Epr protein, Staphylococcus capitis  0   *Bacterial Proteins *Drug Resistance, Microbial. J Bacteriol 1997 Jul;179(13):4311-8
Ard2 protein, Streptomyces capreolus  EC 2.7.1.-   *Bacterial Proteins *Phosphotransferases Drug Resistance, Microbial. Eur J Biochem 1997 Apr 1;245(1):54-63
Pap1 protein, S pombe  0   *Schizosaccharomyces pombe Proteins *Basic-Leucine Zipper Transcription Factors Drug Resistance, Microbial Leucine Zippers. Biochem Biophys Res Commun 1997 Feb 24;231(3):553-6
MRD protein, Streptomyces lavendulae  0   *Bacterial Proteins *Membrane Transport Proteins Drug Resistance, Microbial. J Bacteriol 1997 Mar;179(5):1796-804
NimB protein, Bacteroides fragilis  0   *Bacterial Proteins *Drug Resistance, Microbial. J Clin Microbiol 1996 Sep;34(9):2078-84
TlrD protein, Streptomyces fradiae  EC 2.1.1.-   *Bacterial Proteins *Methyltransferases Drug Resistance, Microbial. Gene 1996 Nov 21;180(1-2):173-6
mecR1 protein, Staphylococcus aureus  0   *Bacterial Proteins Drug Resistance, Microbial Signal Transduction. J Bacteriol 1996 Sep;178(18):5464-71
ZmaR protein, Bacillus  EC 2.3.1.-   *Acetyltransferases *Bacterial Proteins Drug Resistance, Microbial. J Bacteriol 1996 Jul;178(14):4266-72
MtrB protein, Streptomyces argillaceus  0   *Bacterial Proteins *Drug Resistance, Microbial. Mol Gen Genet 1996 Jul 26;251(6):692-8
MtrA protein, Bacteria  0   *Bacterial Proteins *ATP-Binding Cassette Transporters Drug Resistance, Microbial. Mol Gen Genet 1996 Jul 26;251(6):692-8
phleomycin resistance protein, Streptoalloteichus hindustanus  0   *Bacterial Proteins Drug Resistance, Microbial. Mol Gen Genet 1996 Apr 24;251(1):23-30
BmrR protein, bacteria  0   *Bacterial Proteins *Trans-Activators DNA-Binding Proteins Drug Resistance, Microbial Drug Resistance, Multiple. J Biol Chem 1994 Nov 11;269(45):28506-13
cph protein, Saccharothrix mutabilis  EC 2.7.1.-   *Bacterial Proteins *Phosphotransferases (Alcohol Group Acceptor) Drug Resistance, Microbial. Gene 1995 Dec 29;167(1-2):121-6
capreomycin N-acetyltransferase  EC 2.3.1.-   *Acetyltransferases *Bacterial Proteins Drug Resistance, Microbial. Gene 1995 Dec 29;167(1-2):121-6
tetL protein, Enterococcus faecalis  0   *Bacterial Proteins *Drug Resistance, Microbial. Gene 1995 Jul 4;160(1):89-93
NimC protein, Bacteroides thetaiotaomicron  0   *Bacterial Proteins *Drug Resistance, Microbial. Microbiology 1995 Apr;141( Pt 4):927-35
nisG protein, Lactococcus lactis  0   *Bacterial Proteins *ATP-Binding Cassette Transporters Drug Resistance, Microbial. Appl Environ Microbiol 1995 Mar;61(3):1082-9
NisF protein, Lactococcus lactis  0   *Bacterial Proteins *ATP-Binding Cassette Transporters Drug Resistance, Microbial. Appl Environ Microbiol 1995 Mar;61(3):1082-9
NisE protein, Lactococcus lactis  0   *Bacterial Proteins *ATP-Binding Cassette Transporters Drug Resistance, Microbial. Appl Environ Microbiol 1995 Mar;61(3):1082-9
BFR1 protein, S pombe  0   *ATP-Binding Cassette Transporters *Schizosaccharomyces pombe Proteins Drug Resistance, Microbial. J Bacteriol 1995 Mar;177(6):1536-43
VanZ protein, Enterococcus faecium  0   *Bacterial Proteins Drug Resistance, Microbial. Gene 1995 Feb 27;154(1):87-92
VanX dipeptidase  EC 3.4.17.14   *Bacterial Proteins *Serine-Type D-Ala-D-Ala Carboxypeptidase Drug Resistance, Microbial. Mol Microbiol 1994 Sep;13(6):1065-70
phosphatidylinositol-ceramide phosphoinositol transferase  EC 2.4.1.-   *Hexosyltransferases Drug Resistance, Microbial Saccharomyces cerevisiae Proteins Schizosaccharomyces pombe Proteins. J Bacteriol 1994 Aug;176(16):5181-3
mcrA protein, Streptomyces lavendulae  EC 1.5.3.-   *Bacterial Proteins *Oxidoreductases Drug Resistance, Microbial. J Bacteriol 1994 Jul;176(14):4448-54
mtrR protein, Neisseria gonorrhoeae  155359-99-2   *Bacterial Proteins *Repressor Proteins DNA-Binding Proteins Drug Resistance, Microbial. Mol Microbiol 1994 Feb;11(4):769-75
TETP protein, Clostridium perfringens  0   *Bacterial Proteins Drug Resistance, Microbial. Mol Microbiol 1994 Jan;11(2):403-15
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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