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Echinomycin

More information in Books or onNLM PubMed
Definition: A cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis.     
Pharmacological Action Anti-Bacterial Agents; Antibiotics, Antineoplastic; Nucleic Acid Synthesis Inhibitors 		Other names Quinomycin A; NSC526417; NSC 526417; NSC-526417
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
YK2000  0   Echinomycin/*analogs & derivatives. Int J Antimicrob Agents 2004 Dec;24(6):613-5
epoxyquinomycin B  0   Echinomycin/*analogs & derivatives. Chem Rev 2004 Jun;104(6):2857-99
S-methylechinomycin  0   Echinomycin/*analogs & derivatives. Bioorg Med Chem Lett 1998 Apr 7;8(7):731-4
echinoserine  0   *Echinomycin. J Antibiot (Tokyo) 1995 Jul;48(7):619-25
quinaldopeptin  130743-07-6   Echinomycin/*analogs & derivatives. J Antibiot (Tokyo) 1990;43(7):796
UK 65662  120832-02-2   Echinomycin/*analogs & derivatives. J Antibiot (Tokyo) 1989;42(2):206
UK 63598  120796-23-8   Echinomycin/*analogs & derivatives. J Antibiot (Tokyo) 1989;42(2):206
UK 63052 complex  0   Echinomycin/*analogs & derivatives. J Antibiot (Tokyo) 1989;42(2):206
UK 63052  120763-23-7   Echinomycin/*analogs & derivatives. J Antibiot (Tokyo) 1989;42(2):206
2QN-echinomycin  77196-00-0 Quinomycin A, 1-(N-(2-quinolinylcarbonyl)-D-serine)-5-(N-(2-quinolinylcarbonyl)-D-serine)  Echinomycin/*analogs & derivatives. Biochem J 1980;191(3):729
1QN-echinomycin  77195-99-4 Quinomycin A, 1-(N-(2-quinolinylcarbonyl)-D-serine)  Echinomycin/*analogs & derivatives. Biochem J 1980;191(3):729
quinomycin  11113-76-1 Quinomycin  Echinomycin/*analogs & derivatives. Anal Biochem 89(1):213;1978; J Antibiot (Tokyo) 28(4):332;1975; J Antibiot (Tokyo) 29(11):1246;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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