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Enzyme Induction

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Definition: An increase in the rate of synthesis of an enzyme due to the presence of an inducer which acts to derepress the gene responsible for enzyme synthesis.  IM for general only; NIM with specific enzyme /biosyn (IM)    Other names Induction, Enzyme
 
SubstanceCAS Registry & nameCategoriesSource
N-methoxyindole-3-carbinol  0   *Indoles Enzyme Induction. Nutr Cancer 2000 ;36(1):112-21
HP 228  109022-88-0   *Oligopeptides Enzyme Induction. J Pharmacol Exp Ther 1995 Nov;275(2):584-91
5-ethyl-5-phenyloxazolidinedione  92288-54-5   *Oxazoles Enzyme Induction. Chem Res Toxicol 1993 Mar-Apr;6(2):188-96
3-benzylpyridine  620-95-1   *Benzyl Compounds *Pyridines Cytochrome P-450 Enzyme System Enzyme Induction. Biochem Pharmacol 1992 May 28;43(10):2151-9
2-benzylpyridine  101-82-6   *Benzyl Compounds *Pyridines Cytochrome P-450 Enzyme System Enzyme Induction. Biochem Pharmacol 1992 May 28;43(10):2151-9
4-benzylpyridine  2116-65-6   *Pyridines Aminopyrine N-Demethylase/antagonists & inhibitors Cytochrome P-450 Enzyme System Enzyme Induction. Biochem Pharmacol 1992 May 28;43(10):2151-9
croton factor F2  67492-54-0   *Phorbol Esters Enzyme Induction. J Cancer Res Clin Oncol 1980;98(1):9
croton factor F1  53202-98-5   *Phorbol Esters Enzyme Induction. J Cancer Res Clin Oncol 1980;98(1):9
flumecinol  56430-99-0 benzenemethanol, alpha-ethyl-alpha-phenyl-3-(trifluoromethyl)  *Benzhydryl Compounds Enzyme Induction/drug effects. Eur J Clin Pharmacol 13(4):299;1978
benzobarbital  744-80-9 5-ethyl-1-benzoyl-5-phenylbarbituric acid  *Barbiturates Enzyme Induction/drug effects.
Pharma Action Anti-Arrhythmia Agents ; Anti-Inflammatory Agents, Non-Steroidal ; Anticonvulsants ; Radiation-Protective Agents
Genetika 14(9):1564;1978; Neur Neurochir Pol 9(6):727;1975; Psychiatria Polska 7(1):75;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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