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Epistasis, Genetic

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Definition: A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.     
See Also Genes, Modifier; Multifactorial Inheritance 		Other names Genes, Hypostatic; Genes, Epistatic; Epistatic Deviation; Deviation, Epistatic; Non-Allelic Gene Interaction; Non Allelic Gene Interactions; Interactions, Non-Allelic Gene; Interactions, Epistatic Gene-Gene; Interaction, Non-Allelic Gene; Interaction, Epistatic Gene-Gene; Hypostatic Genes; Hypostatic Gene; Gene, Hypostatic; Gene Interactions, Non-Allelic; Gene Interaction, Non-Allelic; Gene Gene Interactions, Epistatic; Gene Gene Interaction, Epistatic; Gene, Epistatic; Epistatic Genes; Epistatic Gene-Gene Interactions

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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