encyclopedia of medical concepts
ψ 

Epoxide Hydrolases

More information in Books or onNLM PubMed
Definition: Enzymes that catalyze reversibly the formation of an epoxide or arene oxide from a glycol or aromatic diol, respectively.      Other names Epoxide Hydratases; Epoxide Hydrases; Hydrolases, Epoxide; Hydrolase, Styrene Epoxide; Hydrolase, Microsomal Epoxide; Hydratases, Epoxide; Hydrases, Epoxide; Hydrase, 9,10-Epoxypalmitic Acid; Epoxide Hydrolase, Styrene; Epoxide Hydrolase, Microsomal; Acid Hydrase, 9,10-Epoxypalmitic; 9,10 Epoxypalmitic Acid Hydrase; Styrene Epoxide Hydrolase; Microsomal Epoxide Hydrolase; 9,10-Epoxypalmitic Acid Hydrase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea  0   *Phenylurea Compounds *Piperidines Epoxide Hydrolases/antagonists & inhibitors. J Cardiovasc Pharmacol 2011 Mar;57(3):273-81
1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea  0   Niacinamide/*analogs & derivatives Phenylurea Compounds Epoxide Hydrolases/antagonists & inhibitors. Eur J Pharmacol 2011 Mar 1;654(1):68-74
1-(1-acetyl-piperidine-4-yl)-3-adamantan-1-yl-urea  0   Adamantane/*analogs & derivatives Urea/*analogs & derivatives Epoxide Hydrolases/antagonists & inhibitors. Eur J Pharmacol 2011 Mar 1;654(1):68-74
epoxide hydrolase NcsF2, Streptomyces carzinostaticus  EC 3.3.2.-   *Epoxide Hydrolases. Org Lett. 2010 Sep 3;12(17):3816-9
EPHX1 protein, mouse  EC 3.3.2.3.   *Epoxide Hydrolases. Biol Reprod. 2009 Jul;81(1):126-32
EPHX2 protein, rat  EC 3.3.2.3   *Epoxide Hydrolases. J Biol Chem 1993 Aug 15;268(23):17623-7
4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid  0   *Benzoic Acids Urea/*analogs & derivatives Epoxide Hydrolases/antagonists & inhibitors. J Med Chem 2007 Aug 9;50(16):3825-40
EPHX1 protein, human  EC 3.3.2.9   *Epoxide Hydrolases. Am J Epidemiol 2007 Aug 1;166(3):313-22
Ephx2 protein, mouse  EC 3.3.2.3   *Epoxide Hydrolases. Biol Reprod 2005 Apr;72(4):968-75
EPHX2 protein, human  EC 3.3.2.3   *Epoxide Hydrolases. Hum Mol Genet 2005 Oct 1;14(19):2829-37
1-adamantan-3-(5-(2-(2-ethylethoxy)ethoxy)pentyl)urea  0   Adamantane/*analogs & derivatives Urea/*analogs & derivatives Epoxide Hydrolases/antagonists & inhibitors. Proc Natl Acad Sci U S A 2005 Jul 112;102(28):9772-7
12-(3-adamantan-1-ylureido)dodecanoic acid butyl ester  0   Adamantane/*analogs & derivatives Urea/*analogs & derivatives Epoxide Hydrolases/antagonists & inhibitors. Proc Natl Acad Sci U S A 2005 Jul 112;102(28):9772-7
YNR064c protein, S cerevisiae  EC 3.3.2.3   *Epoxide Hydrolases *Saccharomyces cerevisiae Proteins. Biochim Biophys Acta 2005 May 15;1748(2):213-21
1-cyclohexyl-3-dodecylurea  0   Urea/*analogs & derivatives Epoxide Hydrolases/antagonists & inhibitors. Proc Natl Acad Sci U S A 2002 Feb 19;99(4):2222-7
4-phenylchalcone oxide  0   *Chalcones Epoxide Hydrolases. Am J Physiol 1999 Nov;277(5 Pt 2):H2098-H2108
limonene-1,2-epoxide hydrolase  EC 3.3.2.-   *Bacterial Proteins *Epoxide Hydrolases. FEBS Lett 1998 Nov 6;438(3):293-6
EH-1 protein, Tobacco mosaic virus  EC 3.3.2.3   *Epoxide Hydrolases *Viral Proteins. Plant J 1998 Sep;15(5):647-56
hepoxilin epoxide hydrolase  EC 3.3.2.-   *Epoxide Hydrolases. Proc Natl Acad Sci USA 1990;87(8):3037
juvenile hormone epoxide hydrolase  EC 3.3.2.-   *Epoxide Hydrolases. Anal Biochem 1988;169(1):81
stilbene oxide hydrolase  EC 3.3.2.-   *Epoxide Hydrolases. Biochem Pharmacol 1986;35(5):839
leukotriene A4 hydrolase  EC 3.3.2.-   *Epoxide Hydrolases. J Biol Chem 1984;259(20):12339
butadiene monoxide hydrolase  EC 3.3.2.-   *Epoxide Hydrolases. Adv Exp Med Biol 1981;136(A):437
styrene oxide hydratase  EC 3.3.2.-   *Epoxide Hydrolases. Arch Tox (suppl 1):295;1978
cholesterol-5 alpha,6 alpha-epoxide hydrase  EC 3.3.2.-   *Epoxide Hydrolases. J Invest Dermatol 66(2):112;1976; Science 186(4170):1216;1974
benzo(a)pyrene-4,5-oxide hydratase  EC 3.3.2.-   *Epoxide Hydrolases. Arch Biochem Biophys 168(2):722;1975; Glutathione: metabolism and function W3 KR45:6:339;1975

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy