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Ergolines

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Definition: A series of structurally-related alkaloids that contain the ergoline backbone structure.     
Examples Ergonovine; Lisuride; Lysergic Acid; Metergoline; Methysergide; Nicergoline; Pergolide 		Other names Ergoline
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(8'-hydroxy-2'-methyl-5'-(2-methylpropyl)-3',6'-dioxo-7'-(phenylmethyl)oxazolidino(2,3-c)piperazin-2'-yl) 6-methylergoline-8-carboxamide  0   *Ergolines Receptors, Serotonin, 5-HT1/antagonists & inhibitors. J Med Chem 2003 Nov 20;46(24):5117-20
1,2,3,4,5,6-hexa(6-methyl-8-(diethylcarbamoylamino)-ergoline-1-yl-methyl)  0   *Carbamates *Ergolines. Bioorg Med Chem 2002 Feb;10(2):415-24
1-bromo-2,2-di(6-methyl-methyl-8-(diethylcarbamoylamino)-ergoline-1-yl-methyl)-3-(6-methyl-8-(diethylcarbamoylamino)-ergoline-1-yl)propane  0   *Carbamates *Ergolines. Bioorg Med Chem 2002 Feb;10(2):415-24
BAM 1120  0   *Ergolines. Methods Find Exp Clin Pharmacol 1998 Sep;20(7):561-6
1-methoxyagroclavine  0   *Ergolines. Bioorg Med Chem Lett 1998 Mar 17;8(6):569-74
(5R,8R,10R)-6-methyl-8-(1,2,4-triazol-1-ylmethyl)ergoline  0   *Ergolines *Triazoles. Clin Neuropharmacol 1998 Jan-Feb;21(1):35-40
SDZ MAR 327  0   *Ergolines. J Pharm Sci 1998 Jan;87(1):123-4
ergotoxine  8006-25-5   *Ergolines Ergot Alkaloids. Nervenarzt 1986;57(3):174
ergocornine  564-36-3   *Ergolines. J Exp Zool 1986;237(1):25
ergocristine  511-08-0   *Ergolines. Nervenarzt 1986;57(3):174.
ergocryptine  511-09-1   *Ergolines.
Pharma Action Dopamine Agonists 		J Allergy Clin Immunol 1984;74(6):812
4-hydroxyamesergide  121566-75-4   *Ergolines. J Pharm Pharmacol 1994 Mar;46(3):226-9
lergotrile mesylate  51473-23-5 Ergoline-8-acetonitrile, 2-chloro-6-methyl-, (8beta)-, monomethanesulfonate  *Ergolines.
4-((2-(cyclohexylcarbamoyl)ethyl)methylamino)-1-isopropyl-1,3,4,5-tetrahydrobenz(cd)indole  150403-75-1   *Ergolines. J Med Chem 1993 Sep 3;36(18):2671-5
4-(9,10-didehydroergolin-8-yl)methylpiperazine-2,6-dione  131816-89-2   *Ergolines. J Pharm Biomed Anal 1993 Apr-May;11(4-5):393-9
FCE 24220  121532-44-3   *Ergolines *Hydantoins. Drug Metabol Drug Interact 1992;10(3):185-97
FCE 23884  107052-56-2 2,6-Piperazinedione, 4-(((8beta)-9,10-didehydro-6-methylergolin-8-yl)methyl)  *Ergolines. J Pharmacol Exp Ther 1991;259(1):345
RU 41656  134377-22-3 RU 41656  *Ergolines. Psychopharmacology (Berl) 1991;104(1):75
mergocriptine  81968-16-3   *Ergolines. Jpn J Pharmacol 1990;54(2):163
amesergide  121588-75-8 Ergoline-8-carboxamide, N-cyclohexyl-6-methyl-1-(1-methylethyl)-, (8beta)  *Ergolines. Life Sci 1990;47(23):2089
LY 178210  114943-19-0 Benz(cd)indole-6-carboxamide, 4-(dipropylamino)-1,3,4,5-tetrahydro  *Ergolines. Life Sci 1990;47(15):1331
N-(2,6-dimethylergoline-8-yl)-2,2-dimethylpropanamide  120478-64-0   *Ergolines. J Pharmacol Exp Ther 1990;252(1):279
lumelysergol  7079-87-0   *Ergolines. Pol J Pharmacol Pharm 1988;40(6):593
lysergol  602-85-7   *Ergolines. Pol J Pharmacol Pharm 1988;40(6):593
FCE 22716  95688-34-9   *Ergolines *Hydantoins. Pharmacology 1989;38(2):78
CQA 206-291  93822-42-5   *Ergolines. Clin Neuropharmacol 1989;12(1):60
N-(2-chloro-6-methylergoline-8-yl)-2,2-dimethylpropanamide  120478-65-1   *Ergolines. Pharmacopsychiatry 1988;21(6):312
FCE 24379  113869-44-6   *Ergolines Uracil/*analogs & derivatives. Drugs 1988;36 Suppl 1:105
2,3-dihydrolysergine  114249-74-0   *Ergolines. J Med Chem 1988;31(8):1512
proterguride  77650-95-4   *Ergolines Urea/*analogs & derivatives. Xenobiotica 1988;18(1):41
CK 204-933  90408-58-5 Ergoline, 9,10-didehydro-2,6-dimethyl-8-((2-pyridinylthio)methyl)-, (8beta)  *Ergolines. J Neural Transm 1987;69(3-4):179
CQP 201-403  104317-90-0 Sulfamide, N,N-dimethyl-N'-((8alpha)-6-propylergolin-8-yl)  *Ergolines. Br J Clin Pharmacol 1986;22(1):1
9,10-ergolene  6878-09-7   *Ergolines. Experientia 1986;42(3):327
cabergoline  81409-90-7   *Ergolines.
Pharma Action Antineoplastic Agents ; Antiparkinson Agents ; Dopamine Agonists 		Cancer Lett 1985;28(2):237DOSTINEX; CABERGOLINE
8-((4-(4-methoxyphenyl)-1-piperazinyl)methyl)-6-methylergoline  56552-51-3   *Ergolines. Eur J Pharmacol 1984;106(1):79
GYKI 32887  78463-86-2   *Ergolines. Neuropharmacology 1984;23(5):511
6-methyl-8 alpha-N-methylsulfamoylaminoergoline  88374-72-5 Sulfamide, N-methyl-N'-((8alpha)-6-methylergolin-8-yl)  *Ergolines. Eur J Pharmacol 1983;95(1-2):101
2-cyano-3-(6-methylergolin-8 beta-yl)propionamide  74627-35-3 Ergoline-8-propanamide, alpha-cyano-6-methyl-, (8beta)  *Ergolines. Arzneimittelforsch 1983;33(8):1098
N-propyl-9-oxaergoline  85351-27-5 9-Oxaergoline, 6-propyl-, monohydrochloride  *Ergolines. Eur J Pharmacol 1983;87(2-3):183
epoxyagroclavine-1  82564-34-9 Ergoline, 8,9-epoxy-6,8-dimethyl-, (8beta,9beta,10beta)  *Ergolines. Prikl Biokhim Mikrobiol 1982;18(4):535
6-ethyl-9-oxaergoline  81244-91-9 9-Oxaergoline, 6-ethyl  *Ergolines. Life Sci 1982;30(21):1847
6-propyl-8-ergolinylacetamide  67658-45-1 Ergoline-8-acetamide, 6-propyl-, (8beta)  *Ergolines. Arzneimittelforsch 1982;32(4):365
costaclavin  436-41-9   *Ergolines. Mikrobiologiia 1981;50(6):1046
LY 53857  60634-51-7   *Ergolines.
Pharma Action Serotonin Antagonists 		Gen Comp Endocrinol 1981;45(3):395
lergotrile  36945-03-6   *Ergolines. Life Sci 1981;29(6):575
CQ 32085  64795-35-3   *Ergolines.
Pharma Action Antiparkinson Agents ; Serotonin Antagonists ; Dopamine Agonists 		J Neural Transm 1981;51(1-2):51
etisulergine  64795-23-9   *Ergolines. J Neural Transm 1981;51(1-2):3
N-desmethyl lergotrile  56867-81-3 (8 beta)-2-chloroergoline-8-acetonitrile  *Ergolines. Appl Environ Microbiol 1979;38(5):891
3,12-dihydroroquefortine  58735-66-3 2H-Pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4(3H,5aH)-dione, 10b-(1,1-dimethyl-2-propenyl)-6,10b,11,11a-tetrahydro-3-(1H-imidazol-4-ylmethyl)  *Ergolines. Biokhimiia 44(9):1691;1979
CH 29717  59032-40-5 N,N-dimethyl-N'-((8 alpha)-6-methylergolin-8-yl)sulfamide  *Ergolines. Experientia 34(10):1330;1978
isofumigaclavine B  58800-20-7   *Ergolines Mycotoxins. J Agric Food Chem 24(4):865;1976
CM 29-712  25810-52-0 6-methyl-8 alpha-1-cyanomethylergoline  *Ergolines. Br J Pharm 62(3):395;1978; Psychopharm 57(3):227;1978
CF 25397  57935-49-6 9,10-didehydro-6-methyl-8 beta-(2-pyridylthiomethyl)ergoline  *Ergolines. Arch Neurol 1980;37(4):204; Brit J Pharmacol 56(3):371;1976; Fed Proc 37(8):2207;1978; J Pharm Pharmacol 29:632;1977; Psychopharm 57(3):227;1978
paliclavine  52052-66-1 (4R)-(4 alpha,5 beta(R*)))-1,3,4,5-tetrahydro-4-(methylamino)-alpha-(1-methylethenyl)benz(cd) indole-5-methanol  *Ergolines. Helv Chim Acta 58(8):2484;1975; Helv Chim Acta 58(8):2492;1975
isofumigaclavine A  58800-19-4   *Ergolines Mycotoxins. Ann Nutr Alim 31(4,5,6):693;1977; J Agric Food Chem 24(4):865;1976
elymoclavine  548-43-6 8,9-didehydro-6-methylergoline-8-methanol  *Ergolines. J Anim Sci 41(6):1700;1975; J Pharm Sci 66(9):1340;1977
chanoclavine  2390-99-0   *Ergolines. Folia Microbiol 20(4):365;1975; J Am Chem Soc 96(6):1898;1974; Pharmazie 27(12):773;1972
ergotoxine, magnesium dehydrocholate, magnesium glutamate, magnesium nicotinate, quinidine sulfate, quinine sulfate, theobromine drug combination  0   *Ergolines *Magnesium *Quinidine *Quinine *Theobromine Drug Combinations. Medicina Arhiv 25(4-6):49;1971
agroclavine  548-42-5   *Ergolines.
D-6-methyl-8-ergolin-1-ylacetic acid amide tartrate  33529-63-4 Ergoline-8-acetamide, 6-methyl-, (8 beta)  *Ergolines. Arzneim Forsch 23(4):617;1973; Cancer Res 37(11):3932;1977; Endocrinol Exp (Bratisl) 11(3):183;1977; Physiol Bohemoslav 23(1):113;1974
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