encyclopedia of medical concepts
ψ 

Erythromycin

More information in Books or onNLM PubMed
Definition: A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.     
Pharmacological Action Anti-Bacterial Agents; Gastrointestinal Agents; Protein Synthesis Inhibitors
Examples Azithromycin; Clarithromycin; Erythromycin Estolate; Erythromycin Ethylsuccinate; Ketolides; Roxithromycin 		Other names TStat; T Stat; Phosphate, Erythromycin; Lactate, Erythromycin; C, Erythromycin; T-Stat; Erythromycin Phosphate; Erythromycin Lactate; Erythromycin C; Erythromycin A; Erymax; Ilotycin; ErycetteDrugs* : E-MYCIN; T-STAT; ERYTHRA-DERM; ERYGEL; EMGEL; ROBIMYCIN; ERYTHROMYCIN; ERYTHRO-STATIN; PCE; ERYDERM; ERY-TAB; E-SOLVE 2; ILOTYCIN; ERYC SPRINKLES; ERYCETTE; E-BASE; E-GLADES; A/T/S; ERYMAX; SANSAC
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
9a-(3-(7-chloroquinolin-4-ylamino)propyl)-9-deoxo-9-dihydro-9a-aza-9a-homoerythromycin A  0   *Aminoquinolines Erythromycin/*analogs & derivatives. J Med Chem. 2012 Feb 9;55(3):1389-401.
(8R,9S)-8,9-dihydro-6,9-epoxy-8,9-anhydropseudoerythromycin A  0   Erythromycin/*analogs & derivatives Macrolides. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3373-6
6-(2''-hydroxy-3''-(2-(quinolin-6-ylamino)ethylamino)propoxy)-3-oxo-8a-aza-8a-homoerythromycin A  0   Erythromycin/*analogs & derivatives. J Med Chem 2010 Aug 12;53(15):5868-80
8a-aza-8a-homoerythromycin  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo). 2009 Mar;62(3):133-44
erythronolide I  0   Erythromycin/*analogs & derivatives. Org Lett 2009 Mar 19;11(6):1353-6
erythronolide H  0   Erythromycin/*analogs & derivatives. Org Lett 2009 Mar 19;11(6):1353-6
anhydroerythromycin A  0   Erythromycin/*analogs & derivatives. J Chromatogr 1985 Aug 23;330(2):275-86
15-azidoerythromycin A  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 2006 Jul;59(7):392-401
15-fluoroerythromycin A  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 2006 Jul;59(7):392-401
EM703  0   Erythromycin/*analogs & derivatives. Respir Res 2006;7:(dup#12):16
erythromycin A 9-oxime desosaminehydrazinium salt  0   *Hydrazines Erythromycin/*analogs & derivatives. J Antibiot (Tokyo). 2005 Aug;58(8):539-44
erythromycin B enol ether 2'-ethyl succinate  0   Erythromycin/*analogs & derivatives. J Med Chem 2005 Jun 2;48(11):3878-84
erythromycin B 2'-ethyl succinate  0   Erythromycin/*analogs & derivatives. J Med Chem 2005 Jun 2;48(11):3878-84
erythromycin B enol ethyl ether  0   Erythromycin/*analogs & derivatives. J Med Chem 2005 Jun 2;48(11):3878-84
KC 11458  0   Erythromycin/*analogs & derivatives. Aliment Pharmacol Ther 2004 Aug 1;20(3):333-8
7-hydroxy-6-demethyl-6-deoxyerythromycin D  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 2004 Jan;57(1):64-7
11-deoxy-11-(carboxy(3,4-dichlorophenethyl)amino)-3-O-(4-methyloxazolidin-2-one-3-yl)carbamoyl-5-O-(3'-N-desmethyl-3'-N-cyclopropylmethyl)desosaminyl-6-O-methylerythronolide A 11,12-(cyclic carbamate)  0   Erythromycin/*analogs & derivatives Gonadotropin-Releasing Hormone/antagonists & inhibitors. J Med Chem 2004 Feb 26;47(5):1085-97
(N-methyl) erythromycin  0   Erythromycin/*analogs & derivatives. J Clin Pharmacol. 2003 Oct;43(10):1091-100
5-O-desosaminyl-3-O-(3-pyridyl)acetyl-6-O-methylerythronolide A 11,12-cyclic carbamate  0   Erythromycin/*analogs & derivatives. J Med Chem 2003 Jun 19;46(13):2706-15
5-O-desosaminyl-9-dihydro-3O-(3-pyridyl)acetylerythronolide A 6,9-11,12-dicyclic carbonate  0   Erythromycin/*analogs & derivatives. J Med Chem 2003 Jun 19;46(13):2706-15
erythromycin G  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 2003 Mar;56(3):280-8
2-desmethyl-2-methoxy-6-deoxyerythronolide B  0   Erythromycin/*analogs & derivatives. J Am Chem Soc 2002 May 15;124(19):5268-9
TEA 0770  0   Erythromycin/*analogs & derivatives. J Med Chem 2001 Nov 22;44(24):4027-30
EM536  0   Erythromycin/*analogs & derivatives. Chem Pharm Bull (Tokyo) 2000 Nov;48(11):1835-7
6-O-methylerythromycin D  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1999 Sep;52(9):831-4
12-O-methylerythromycin A  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1999 Oct;52(10):908-12
9-dihydro-12-O-methylerythromycin A  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1999 Oct;52(10):908-12
6-deoxy-13-cyclopropyl-erythromycin B  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1999 Aug;52(8):742-7
2-oxo-12,16-dimethyl-3,5,10,14,15-icosanepentol hemiketal  0   Erythromycin/*analogs & derivatives Mycotoxins. Nat Toxins 1999 ;7(1):31-8
13-cyclopentyl-13-desethyl-erythromycin B  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1999 Feb;52(2):190-2
12-desmethyl-12-ethyl-6-deoxyerythronolide  0   Erythromycin/*analogs & derivatives. Bioorg Med Chem 1998 Aug;6(8):1171-7
ABT 229  0   Erythromycin/*analogs & derivatives. Aliment Pharmacol Ther 1997 Dec;11(6):1077-86
9-deoxo-4''-deoxy-3'-N--desmethyl-3'-N-ethanol-6,9-epoxyerythromycin A  0   Erythromycin/*analogs & derivatives. J Med Chem 1998 Aug 27;41(18):3402-8
9-deoxo-4''-deoxy-3'-N-desmethyl-3'-ethyl-6,9-epoxyerythromycin A  0   Erythromycin/*analogs & derivatives. J Med Chem 1998 Aug 27;41(18):3402-8
6,12-dideoxyerythromycin A  0   Erythromycin/*analogs & derivatives. Appl Microbiol Biotechnol 1998 Jun;49(6):725-31
6-deoxyerythromycin D  0   Erythromycin/*analogs & derivatives. Appl Microbiol Biotechnol 1998 Jun;49(6):725-31
2,3-anhydro-5-O-desosaminyl--11-((3-(4-aminophenyl)-2-propenyl)hydrazo)-6-O-methylerythronolide A 11,12-carbamate  0   Erythromycin/*analogs & derivatives. J Med Chem 1998 May 7;41(10):1660-70
2,3-anhydro-5-O-desosaminyl-11-((3-(4-nitrophenyl)-2-propenyl)hydrazo)-6-O-methylerythronolide A 11,12-carbamate  0   Erythromycin/*analogs & derivatives. J Med Chem 1998 May 7;41(10):1660-70
erythromycin(OSn(tBu)2)2O  0   *Organotin Compounds Erythromycin/*analogs & derivatives. J Magn Reson 1997 Jan;124(1):218-22
8-deoxyankolide  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1997 Aug;50(8):690-2
GM 611  0   Erythromycin/*analogs & derivatives. Am J Physiol 1996 Dec;271(6 Pt 1):G1003-16
9-deoxo-9a-aza--9a-homoerythromicin A 6,9-cyclic imino ether  0   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1996 Oct;49(10):1066-9
erythromycin A isoxazoline  0   *Isoxazoles Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1996 Sep;49(9):938-40
technetium Tc 99m erthyromycin lactobionate  0   *Organotechnetium Compounds Erythromycin/*analogs & derivatives. Nucl Med Biol 1996 Apr;23(3):291-3
6-deoxysporeamicin A  0   Erythromycin/analogs & derivatives. J Antibiot (Tokyo) 1996 May;49(5):493-5
kujimycin B  30042-37-6   Erythromycin/*analogs & derivatives Macrolides.
kujimycin A  33955-27-0   Erythromycin/*analogs & derivatives Macrolides.
erythromycin A methoxime  53066-26-5   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1996 Mar;49(3):318-20
erythromycin nalidixate  0   Erythromycin/*analogs & derivatives Nalidixic Acid/*analogs & derivatives. Arzneimittelforschung 1995 Jul;45(7):813-4
benzoyl peroxide, erythromycin drug combination  0   *Benzoyl Peroxide *Erythromycin Drug Combinations. Drug Ther Bull 1995 Aug;33(8):62-4BENZAMYCIN; BENZAMYCIN PAK; ERYTHROMYCIN AND BENZOYL PEROXIDE
L 708365  0   Erythromycin/analogs & derivatives. J Antibiot (Tokyo) 1995 Oct;48(10):1141-7
L 708299  0   Erythromycin/analogs & derivatives. J Antibiot (Tokyo) 1995 Oct;48(10):1141-7
L 701677  0   Erythromycin/analogs & derivatives. J Antibiot (Tokyo) 1995 Oct;48(10):1141-7
8,9-anhydroerythromycin A 6,9-hemiketal  0   Erythromycin/*analogs & derivatives. Regul Pept 1995 Feb 14;55(3):227-35
Idremcinal  110480-13-2 Erythromycin, 8,9-didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-epoxy-N-(1-methylethyl)  Erythromycin/*analogs & derivatives. J Pharmacol Exp Ther 1994 Oct;271(1):574-9
LY 267108  105882-69-7   Erythromycin/*analogs & derivatives. Gastroenterology 1994 Mar;106(3):624-8
11-dehydroxy-9-deoxo-9-hydroxy-11-oxoerythromycin A  150369-31-6   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1993 May;46(5):813-26
6-deoxyerythromycin A  135361-13-6   Erythromycin/*analogs & derivatives. J Antibiot (Tokyo) 1993 Apr;46(4):698-700
technetium Tc 99m erythromycin  0   *Erythromycin *Organotechnetium Compounds. Int J Rad Appl Instrum (B) 1992 Oct;19(7):803-6
erythromycin, ammonium bituminosulfonate drug combination  0   *Quaternary Ammonium Compounds *Erythromycin Drug Combinations. Wien Klin Wochenschr 1992;104(7):218-22AKNE-MYCIN
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy