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Ethidium

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Definition: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.     
Pharmacological Action Enzyme Inhibitors; Fluorescent Dyes; Indicators and Reagents; Nicotinic Antagonists; Trypanocidal Agents 		Other names Ethidium Bromide; Bromide, Homidium; Bromide, Ethidium; Homidium Bromide; Novidium
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3,8-diphenylacetylamino-5-ethyl-6-phenylphenantridinium  0   Ethidium/*analogs & derivatives. J Fluoresc 2009 Nov;19(6):1045-51
3,8-dibenzoylamino-5-ethyl-6-phenylphenantridinium  0   Ethidium/*analogs & derivatives. J Fluoresc 2009 Nov;19(6):1045-51
2-hydroxyethidium  0   Ethidium/*analogs & derivatives. Free Radic Biol Med 2005 Oct 1;39(7):853-63
9-(3-(((arginyl-beta-alanyl)aminocaproyl)keto)phenyl)-2,7-diamino-10-methylphenanthridine  0   Arginine/*analogs & derivatives Ethidium/*analogs & derivatives. J Med Chem 1999 Oct 7;42(20):4042-53
9-(3-((((arginine methyl ester)-beta-alanyl)aminocaproyl)keto)phenyl)-2,7-diamino-10-methylphenanthridine  0   Arginine/*analogs & derivatives Ethidium/*analogs & derivatives. J Med Chem 1999 Oct 7;42(20):4042-53
diethidium  0   Ethidium/*analogs & derivatives. J Biomol Struct Dyn 1996 Aug;14(1):13-9
2-N-(3-aminopropionyl)ethidium  0   Ethidium/*analogs & derivatives. Bioorg Khim 1995 Mar;21(3):197-205
transferrin-ethidium homodimer conjugate  0   *Ethidium *Transferrin. Bioconjug Chem 1991 Jul-Aug;2(4):226-31
dihydroethidium  104821-25-2   Ethidium/*analogs & derivatives. J Histochem Cytochem 1991;39(4):485
ethidium-DNA complex  0   *DNA Ethidium/*analogs & derivatives. Biopolymers 1987;26(5):613
bismethidium spermine  85747-62-2 Phenanthridinium, 6,6'-(1,4-butanediylbis(imino-3,1-propanediylimino-4,1-phenylene))bis(5-ethyl  Ethidium/*analogs & derivatives. Nucleic Acids Res 1983;11(6):1931
des-8-aminoethidium  74444-52-3   Ethidium/*analogs & derivatives. Nucleic Acids Res 1982;10(2):749
des-3-aminoethidium  74444-53-4   Ethidium/*analogs & derivatives. Nucleic Acids Res 1982;10(2):749
ethidium diazide  67620-23-9   *Azides Ethidium/*analogs & derivatives. Biochemistry 17(17);3598;1978; Biochemistry 1981:20(7):1887
ethyl phenedium  68613-54-7   Ethidium/*analogs & derivatives. J Mol Biol 1980;144(2):183
carboxydimidium  66442-94-2   Ethidium/*analogs & derivatives. J Mol Biol 1980;144(2):183
tetramethylethidium  72218-60-1 phenathridinium, 3,8-bis(dimethylamino)-5-ethyl-6-phenyl  Ethidium/*analogs & derivatives. FEBS Lett 1980;122(1):100
3,8-diamino-6-phenyl-phenanthridine  62895-33-4   Ethidium/*analogs & derivatives. Biopolymers 1981;20(1):141
ethidium homodimer  61926-22-5 5,5'- (1,2-ethanediylbis(imino-3,1-propanediyl))bis(3,8-diamino-6-phenylphenanthridinium) dichloride di hydrochloride  Ethidium/*analogs & derivatives.
Pharma Action Intercalating Agents 		Biochemistry 17(24):5071-78;1978
acridine ethidium heterodimer  68942-32-5 Phenanthridinium, 3,8-diamino-5-(3-((3-((3-((6-chloro-2-methoxy-9-acridinyl)amino)propyl)amino)propyl)amino)propyl)-6-phenyl-, chloride, pentahydrochloride  Ethidium/*analogs & derivatives. Biochemistry 17(24):5071;1978
diazido-ethidium  76391-86-1 Phenanthridinium, 3,8-diazido-5-ethyl-6-phenyl-, tetrafluoroborate(1-)  *Diazonium Compounds Ethidium/*analogs & derivatives. Biochim Biophys Acta 542(1):108;1978
ethidium-iodouridylyl(3'-5')adenosine  64426-26-2 Adenosine, 5-iodouridylyl-(3'-5')-, ion(1-), 3,8-diamino-5-ethyl-6-phenylphenanthridinium  *Ethidium *Dinucleoside Phosphates. J Mol Biol 114:301;1977
ethidium-5-iodocytidylyl(3'-5')guanosine  64822-98-6 Guanosine, 5-iodocytidylyl-(3'-5')-, ion(1-), 3,8-diamino-5-ethyl-6-phenylphenanthridinium  *Ethidium *Dinucleoside Phosphates. J Mol Biol 114:317;1977
DEMB  54546-19-9 Phenanthridinium, 3,8-diamino-6-ethyl-5-methyl-, bromide  Ethidium/*analogs & derivatives. FEBS Letters 49(2):149;1974

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