encyclopedia of medical concepts
ψ 
ψ 

Exoribonucleases

More information in Books or onNLM PubMed
Definition: A family of enzymes that catalyze the exonucleolytic cleavage of RNA. It includes EC 3.1.13.-, EC 3.1.14.-, EC 3.1.15.-, and EC 3.1.16.-. EC 3.1.-     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
DIS3L2 protein, human  EC 3.1.-   *Exoribonucleases. Nat Genet. 2012 Mar;44(3):277-84.
Nibbler protein, Drosophila  EC 3.1.-   *Exoribonucleases *Drosophila Proteins. Curr Biol. 2011 Nov 22;21(22):1878-87.
Ngl3 protein, S cerevisiae  EC 3.1.-   *Exoribonucleases *Saccharomyces cerevisiae Proteins. Nucleic Acids Res. 2012 Jan;40(2):837-46
PAN2 protein, Drosophila  EC 3.1.-   *Exoribonucleases *Drosophila Proteins. Mol Cell. 2011 Oct 7;44(1):120-33.
PDE12 protein, human  EC 3.1.13.-   *Exoribonucleases. Nucleic Acids Res. 2011 Sep 1;39(17):7750-63
DPD1 protein, Arabidopsis  EC 3.1.-   *Exoribonucleases *Arabidopsis Proteins. Plant Cell 2011 Apr;23(4):1608-24
XRN-1 protein, C elegans  EC 3.1.-   *Exoribonucleases *Caenorhabditis elegans Proteins. Dev Cell 2011 Mar 15;20(3):388-96
PAN2 protein, human  EC 3.1.13.4   *Exoribonucleases.
XRN-2 protein, C elegans  EC 3.1.11.-   *Exoribonucleases *Caenorhabditis elegans Proteins. Nature. 2009 Sep 24;461(7263):546-9
dis3 protein, S pombe  EC 3.1.13.-   *Exoribonucleases *Schizosaccharomyces pombe Proteins.
DIS3 protein, S cerevisiae  EC 3.1.13.-   *Exoribonucleases *Saccharomyces cerevisiae Proteins.
Rai1 protein, S pombe  EC 3.1.-   *Exoribonucleases *Schizosaccharomyces pombe Proteins. Nature. 2009 Apr 9;458(7239):784-8
Rat1 protein, S pombe  EC 3.1.-   *Exoribonucleases *Schizosaccharomyces pombe Proteins. Nature. 2009 Apr 9;458(7239):784-8
cNOT6 protein, human  EC 3.1.-   *Exoribonucleases. Cancer Lett 2009 Jan 18;273(2):281-91
SDN1 protein, Arabidopsis  Ec 3.1.-   *Exoribonucleases *Arabidopsis Proteins. Science 2008 Sep 12;321(5895):1490-2
Rex1 exonuclease, S cerevisiae  EC 3.1.1-   *Exoribonucleases *Saccharomyces cerevisiae Proteins. RNA 2008 Jun;14(6):1214-27
Xrn3 protein, Arabidopsis  EC 3.1.-   *Exoribonucleases *Arabidopsis Proteins. Plant Cell 2007 Nov;19(11):3451-61
nsp14 protein, SARS coronavirus  EC 3.1.-   *Exoribonucleases *Viral Nonstructural Proteins. J Biochem Mol Biol. 2007 Sep 30;40(5):649-55
CER7 protein, Arabidopsis  EC 3.1.-   *Exoribonucleases *Arabidopsis Proteins. Plant Cell 2007 Mar;19(3):904-13
Rrp40 protein, Saccharomyces cerevisiae  EC 3.1.-   *Exoribonucleases *Saccharomyces cerevisiae Proteins Protein Subunits. EMBO Rep. 2007 Jan;8(1):63-9
Eri1 protein, S pombe  EC 3.1.-   *Exoribonucleases. Cell 2006 Jun 2;125(5):873-86
XRN2 protein, Arabidopsis  EC 3.1.-   *Exoribonucleases *Nuclear Proteins *Arabidopsis Proteins.
MUT-7 protein, C elegans  EC 3.1.-   *Exoribonucleases *Caenorhabditis elegans Proteins RNA Interference. Cell 1999 Oct 15;99(2):133-41
mitochondrial RNase II, Arabidopsis  EC 3.1.13.-   *Exoribonucleases *Arabidopsis Proteins Mitochondrial Proteins. Nucleic Acids Res 2004;32(7):5174-82
mitochondrial polynucleotide phosphorylase, Arabidopsis  EC 3.1.13.-   *Exoribonucleases *Arabidopsis Proteins Mitochondrial Proteins. Nucleic Acids Res 2004;32(7):5174-82
rnr protein, E coli  0   *Exoribonucleases *Escherichia coli Proteins.
XRN1 protein, Drosophila  EC 3.1.-   *Exoribonucleases *Drosophila Proteins. Mech Dev 1998 Dec;79(1-2):51-5
RRP41 protein, Arabidopsis  EC 3.1.-   *Exoribonucleases *Arabidopsis Proteins.
Dis3 protein, mouse  0   *Exoribonucleases.
ERI-1 protein, C elegans  EC 3.1.-   *Exoribonucleases *Caenorhabditis elegans Proteins. Nature 2004 Feb 12;427(6975):645-9
ERI1 protein, human  EC 3.1.-   *Exoribonucleases. Nature 2004 Feb 12;427(6975):645-9
Rrp47p protein, human  EC 3.1.-   *Exoribonucleases. Mol Cell Biol. 2003 Oct;23(19):6982-92
PNPT1 protein, human  EC 3.1.13.-   *Exoribonucleases. J Mol Biol 2002 Nov 1;323(4):653-63
XRN1 protein, human  EC 3.1.13.1   *Exoribonucleases *Microtubule-Associated Proteins. RNA 2002 Dec;8(12):1489-501
uridylate-specific 3'-exoribonuclease  EC 3.1.-   *Exoribonucleases. Eukaryot Cell 2002 Feb;1(1):112-8
EXOSC5 protein, human  EC 3.1.13.-   *Antigens, Neoplasm *Antigens, Surface *Exoribonucleases. Cancer Res 2002 Oct 1;62(19):5517-22
EXOSC8 protein, human  EC 3.1.-   *Carrier Proteins *Exoribonucleases. Proc Natl Acad Sci U S A 2002 Apr 16;99(8):5295-300
Xrn1 protein, plant  0   *Exoribonucleases *Plant Proteins. Proc Natl Acad Sci U S A 2000 Dec 5;97(25):13985-90
EXOSC4 protein, human  EC 3.1.-   *Exoribonucleases. J Biol Chem 2000 Oct 20;275(42):33158-66
XRN2 protein, human  EC 3.1.13.1   *Exoribonucleases. Genomics 1999 Jul 15;59(2):252-4
RRP6 protein, S cerevisiae  EC 3.1.13.-   *Exoribonucleases *Saccharomyces cerevisiae Proteins. J Biol Chem 1998 May 22;273(21):13255-63
SKI6 protein, S cerevisiae  0   *Exoribonucleases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1998 May;18(5):2688-96
100RNP-polynucleotide phosphorylase  EC 3.1.13.-   *Exoribonucleases. J Biol Chem 1997 Jul 11;272(28):17648-53
Xrn1 protein, mouse  EC 3.1.-   *DNA-Binding Proteins *Exoribonucleases. Gene 1997 Jun 3;191(2):161-6
U6 nuclease  EC 3.1.13.-   *Exoribonucleases. J Biol Chem 1997 Jan 10;272(2):984-91
PAN3 protein, S cerevisiae  EC 3.1.13.-   *Exoribonucleases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1996 Oct;16(10):5744-53
RRP4 protein, S cerevisiae  0   *Exoribonucleases *Saccharomyces cerevisiae Proteins. Genes Dev 1996 Feb 15;10(4):502-13
DSS1 protein, S cerevisiae  EC 3.1.13.1   *Exoribonucleases *Saccharomyces cerevisiae Proteins. Curr Genet 1995 Jul;28(2):108
oligoribonuclease  EC 3.1.-   *Exoribonucleases. J Bacteriol 1995 Jul;177(14):4137-9
Xrn2 protein, mouse  EC 3.1.11.-   *Exoribonucleases. Nucleic Acids Res 1995 Feb 11;23(3):357-61
dhp1protein, S pombe  EC 3.1.-   *Exoribonucleases *Schizosaccharomyces pombe Proteins. Mol Gen Genet 1994 Apr;243(1):1-8
ribonuclease R  EC 3.1.27.-   *Exoribonucleases. Eur J Biochem 1993 Apr 1;213(1):285-93
VacB protein, Shigella flexneri  151616-69-2   *Bacterial Proteins *Exoribonucleases. J Bacteriol 1992 Oct;174(20):6359-67
EXOSC10 protein, human  EC 3.1.13.-   *Exoribonucleases *Nuclear Proteins. J Exp Med 1992 Oct 1;176(4):973-80
RAT1 protein, S cerevisiae  147883-15-6   *Exoribonucleases *Saccharomyces cerevisiae Proteins. Genes Dev 1992 Jul;6(7):1173-89; Nucleic Acids Symp Ser 1995;(33):79-81
KEM1 protein, S cerevisiae  EC 3.1.11.-   *Exoribonucleases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1991;11(5):2593
oligonucleotidase  EC 3.1.13.3   *Exoribonucleases. Agric Biol Chem 1990;54(3):587
poly(A)-specific ribonuclease  EC 3.1.13.4   *Exoribonucleases Arabidopsis Proteins Saccharomyces cerevisiae Proteins Xenopus Proteins. Eur J Biochem 1989;186(3):591
ribonuclease PH  EC 2.7.7.56   *Exoribonucleases Escherichia coli Proteins. Proc Natl Acad Sci USA 1988;85(13):4710
exoribonuclease T  EC 3.1.13.-   *Exoribonucleases. Proc Natl Acad Sci USA 1984;81(14):4290
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy