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Factor VIII

More information in Books or onNLM PubMed
Definition: Blood-coagulation factor VIII. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.     
Pharmacological Action Coagulants
Examples Factor VIIIa 		Other names Factor VIII Clotting Antigen; Coagulation Factor VIII; Thromboplastinogen; Factor VIII Procoagulant Activity; Factor VIII Coagulant Antigen; HyattC; Hyatt C; HyateC; Hyate C; F VIII C; Speywood Brand of Porcine Factor VIII Preparation; Hyatt-C; Hyate-C; Factor VIIIC; Blood Coagulation Factor VIII; F VIII-C
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
optivate  0   *Factor VIII *von Willebrand Factor Drug Combinations. Biologicals. 2009 Jan;37(1):26-31.
Immunate solvent detergent, human  0   *Factor VIII. Haemophilia 2007 Jan;13(1):9-11
factor VIII, von Willebrand factor drug combination  0   *Factor VIII *von Willebrand Factor Drug Combinations. Haematologica 2004 Sep;89(9):1128-33
factor VIII-von Willebrand factor concentrate 8Y  0   *Factor VIII *von Willebrand Factor. Haemophilia 2002 Sep;8(5):622-8
B-domain-deleted factor VIII  0   *Factor VIII *Peptide Fragments. Biotechnol Prog 2001 Nov-Dec;17(6):1119-27
recombinant FVIII, sugar formulated  0   *Factor VIII *Sucrose. Haemophilia 2001 May;7(3):242-9
recombinant factor VIII SQ  0   *Factor VIII Recombinant Proteins. Thromb Haemost 2001 Jan;85(1):93-100
malmo protocol  0   *Cyclophosphamide *Factor IX *Factor VII *Factor VIII *Immunoglobulin G Drug Combinations. Haematologica 2000 Oct;85(10 Suppl):48-50
BAY 14-2222  0   *Factor VIII *Sucrose. Int J Hematol 2000 Jul;72(1) 101-7
factor VIII Ise  0   *Factor VIII. Thromb Haemost 1997 May;77(5):862-7
hemocytin protein, Bombyx mori  0   *Insect Proteins *Lectins Factor V Factor VIII Bombyx von Willebrand Factor. Biochim Biophys Acta 1995 Feb 21;1260(3):245-58
Vueffe  120947-58-2   *Peptides Factor VIII. Blood Coagul Fibrinolysis 1993 Jun;4(3):459-64
F8 protein, human  0   *Factor VIII Hemophilia A. Genomics 1992 Nov;14(3):585-9
factor VIII delta II  0   *Factor VIII *Peptide Fragments. Eur J Biochem 1991;195(3):637
factor VIII (des-797-1562)  0   *Peptide Fragments Factor VIII. Thromb Res 1987;48(4):439
Kryobulin TIM3  0   *Factor VIII Hot Temperature. Thromb Res 1986;42(4):471
Factor VIII Leiden  0   *Factor VIII. Thromb Haemost 1985;54(3):650
asialo-Factor VIII  0   *Asialoglycoproteins Factor VIII. J Clin Invest 1981;68(2):321
cryoprecipitate coagulum  0   *Factor VIII *Fibrinogen Fibronectins. J Urol 1980;123(5):621
cryobulin  0   *Cryoglobulins *Factor VIII. Wiad Lek 1980;33(7):555

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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