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Farnesol

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Definition: A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
alpha-hydroxyfarnesylphosphonic acid  0   *Phosphonic Acids Farnesol/*analogs & derivatives. Anticancer Res. 2012 Mar;32(3):831-8.
3-(phenylsulfonyl)-4-(4-(1-(2-(3,7,11-trimethyldodeca-2,6,10-trienylthio)benzoyl)pyrrolidine-2-carbonyloxy)but-2-ynyloxy)-1,2,5-oxadiazole-2-oxide  0   *Oxadiazoles Farnesol/*analogs & derivatives Nitric Oxide Donors. Biochem Biophys Res Commun 2011 Jun 17;409(4):752-7
2,3-dihydrohomofarnesal  0   Farnesol/*analogs & derivatives Sex Attractants. J Chem Ecol 2010 Aug;36(8):824-33
3-farnesyl-2-hydroxybenzoic acid  0   *Hydroxybenzoic Acids Farnesol/*analogs & derivatives. J Ethnopharmacol 2007 Apr 20;111(1):1-7
deacetoxyyanuthone A  0   *Cyclohexanes Farnesol/*analogs & derivatives. J Nat Prod 2003 Nov;66(11):1499-500
farnesyl-O-acetylhydroquinone  0   *Hydroquinones Farnesol/*analogs & derivatives. Cancer Lett 2003 Dec 30;202(2):181-92
2,3-dihydrofarnesol  0   Farnesol/*analogs & derivatives. J Nat Prod 2002 Sep;65(9):1319-22
suc-farnesol  0   Farnesol. Metabolism 2001 Nov;50(11):1356-60
mal-farnesol  0   Farnesol/*analogs & derivatives. Metabolism 2001 Nov;50(11):1356-60
farnesyl anthranilate  0   *Anthranilic Acids Farnesol/*analogs & derivatives. Cancer Lett. 2000 Sep 1;157(2):145-53
farnesylthioacetic acid  0   Farnesol/*analogs & derivatives Protein Methyltransferases/antagonists & inhibitors. FEBS Lett 1998 Apr 24;426(3):319-24
farnesylthiosalicylic acid  0   *Salicylic Acids Farnesol/*analogs & derivatives Calcium-Calmodulin-Dependent Protein Kinases/antagonists & inhibitors.
Pharma Action Antineoplastic Agents ; Enzyme Inhibitors
J Med Chem 1995 Apr 14;38(8):1267-72
farnesylthiotriazole  156604-45-4   *Triazoles Farnesol/*analogs & derivatives. Biochemistry 1995 Mar 28;34(12):3916-20
farnesylamine  6784-46-9   Farnesol/*analogs & derivatives. Lipids 1993 Nov;28(11):969-74
3-hydroxy-2,3-dihydrofarnesal  152040-72-7   Farnesol/*analogs & derivatives. Biochem Biophys Res Commun 1993 Nov 15;196(3):1401-5
farnesal  19317-11-4   Farnesol/*analogs & derivatives. Biochem Biophys Res Commun 1993 Nov 15;196(3):1401-5
N-homogeranyl-N-methyl-N'-farnesylformamidine  147315-58-0   *Amidines Farnesol/*analogs & derivatives Farnesyl-Diphosphate Farnesyltransferase/antagonists & inhibitors. J Med Chem 1993 Mar 5;36(5):631-2
(alpha-hydroxyfarnesyl)phosphonic acid  0   *Phosphonic Acids Farnesol/*analogs & derivatives. J Antibiot (Tokyo) 1993 Apr 15;268(11):7617-20
prednisolone farnesylate  118244-44-3   Farnesol/*analogs & derivatives Prednisolone/*analogs & derivatives. J Toxicol Sci 1992 Nov;17 Suppl 3:1-48
farnesyl diazomethyl ketone  83053-30-9   Diazomethane/*analogs & derivatives Farnesol/*analogs & derivatives. Gen Comp Endocrinol 1990;80(2):232
epoxyhomofarnesyl diazoacetate  95043-82-6   *Diazonium Compounds Farnesol/*analogs & derivatives. J Biol Chem 1990;265(32):19800
epoxyfarnesyl diazoacetate  0   *Diazonium Compounds Farnesol/*analogs & derivatives. J Biol Chem 1984;259(5):3219
farnesylacetic acid  23224-49-9   Farnesol/*analogs & derivatives. Gig Sanit 1983;(1):54
cyclopren  61064-89-9   Farnesol/*analogs & derivatives Juvenile Hormones. Rocz Panstw Zakl Hig 1980;31(5):509; Rocz Panstw Zakl Hig 30(4):331;1979
farnesyl methyl ether  15130-76-4   Farnesol/*analogs & derivatives Juvenile Hormones. Acta Embryol Exp 3:295;1977; Gen Comp Endocrinol 1979;39(2):174
7-demethylfarnesyl pyrophosphate  63408-39-9 Diphosphoric acid, mono(3,11-dimethyl-2,6,10-dodecatrienyl) ester, (E,E)  Farnesol/*analogs & derivatives. Biochem Biophys Res Comm 76(2):520;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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