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Fenfluramine

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Definition: A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.     
Pharmacological Action Serotonin Agents; Serotonin Uptake Inhibitors
Examples Norfenfluramine 		Other names Hydrochloride, Fenfluramine; Fenfluramine, R Isomer; Fenfluramine Hydrochloride, R Isomer; Robins Brand of Fenfluramine Hydrochloride; Pondimin; Isomeride; Fenfluramine, R-Isomer; Fenfluramine, (+-)-Isomer; Fenfluramine Hydrochloride, R-Isomer; Fenfluramine Hydrochloride, (+-)-Isomer; Fenfluramine Hydrochloride
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-ethyl-1-(3-(pentafluorosulfanyl)phenyl)propan-2-amine  0   Fenfluramine/*analogs & derivatives. Bioorg Med Chem. 2007 Nov 1;15(21):6659-66
1-(3-(pentafluorosulfanyl)phenyl)propan-2-amine  0   Fenfluramine/*analogs & derivatives. Bioorg Med Chem. 2007 Nov 1;15(21):6659-66
nitrosofenfluramine  0   Fenfluramine/*analogs & derivatives. Med Sci Law. 2004 Jul;44(3):252-63
sennomotokounou  0   *Fenfluramine. Intern Med 2003 Dec;42(12):1188-92
N-methyl fenfluramine  0   Fenfluramine/*analogs & derivatives. J Anal Toxicol 2001 Mar;25(2):88-92
1-(3-trifluoromethylphenyl)-2-(2-carboxymethyl)aminopropane  61471-64-5   Fenfluramine/*analogs & derivatives. Chem Biol Interact 1995 Aug 18;97(3):297-306
1-(3-trifluoromethylphenyl)-2-(N-(2-hydroxyethyl)amino)propane  64176-93-8   Fenfluramine/*analogs & derivatives. Eur J Clin Pharmacol 1991;41(4):339-44
1-(3-trifluoromethylphenyl)-1,2-propanediol  15814-25-2 1,2-Propanediol, 1-(3-(trifluoromethyl)phenyl)  Fenfluramine/*analogs & derivatives. Xenobiotica 1983;13(1):31
1-(3-trifluoromethylphenyl)-2-propanol  621-45-4   Fenfluramine/*analogs & derivatives. Xenobiotica 1983;13(1):31
ITA 213  67987-40-0 2-((ethyl(1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)methyl)-1H-isoindole-1,3(2H)-dione  *Isoindoles Fenfluramine/*analogs & derivatives. Arch Farmacol Toxicol 4(1):170;1978
nortiflorex  52771-23-0   Fenfluramine/*analogs & derivatives. J Chromatogr 152(1):87;1978
flutiorex  59173-25-0 + 1-3'-(trifluoromethylthiophenyl)-2- ethylaminopropane  Fenfluramine/*analogs & derivatives. Br J Clin Pharm 3(1):113;1976; Br J Pharmacol 1979;66(3):506P; Brit J Pharmacol 2(6):541;1976; Eur J Clin Pharm 10(5):325;1976
1204 SE  23189-05-1 Benzoic acid, 3-(aminosulfonyl)-4-chloro-, 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)ethyl ester  Fenfluramine/*analogs & derivatives. Postgrad Med J 51(Suppl 1):91;1975
benfluorex  23602-78-0 N-(2-benzoyloxyethyl)norfenfluramine  Fenfluramine/*analogs & derivatives.
Pharma Action Hypolipidemic Agents ; Appetite Depressants 		Biochem J 166(3):639;1977; Br J Pharm 64(3):377;1978; Curr Med Res Opin 1980;6(7):478; Int J Obesity 2(1):7;1978; J Pharm Pharmacol 24(4):281;1972; J Pharm Pharmacol 28(9):676;1976; Journ Annu Diabetol Hotel Dieu 325;1977; Postgrad Med J (Suppl 1):51;1975 (whole journal); Res Commun Chem Pathol Pharmacol 18(1):95;1977; Sem Hop Paris 1979;55(27-30):1305; Therapie 1979;34(4):445

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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