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Fentanyl

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Definition: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)     
Pharmacological Action Adjuvants, Anesthesia; Analgesics, Opioid; Anesthetics, Intravenous; Narcotics
Examples Alfentanil; Sufentanil 		Other names Phentanyl; R4263; R 4263; Sublimaze; R-4263; Janssen Pharmaceutica Brand of Fentanyl; Fentora; Fentanyl Citrate; Fentanest; Durogesic; Duragesic; Cephalon Brand of Fentanyl Buccal OraVescentDrugs* : FENTANYL CITRATE PRESERVATIVE FREE; SUBLIMAZE PRESERVATIVE FREE; DURAGESIC-12; ABSTRAL; LAZANDA; DURAGESIC-25; SUBSYS; FENTANYL CITRATE; DURAGESIC-75; FENTORA; ONSOLIS; DURAGESIC-50; FENTANYL; FENTANYL-50; FENTANYL-25; ACTIQ; FENTANYL-100; FENTANYL-75; FENTANYL-12; DURAGESIC-100
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
isofentanyl  0   Fentanyl/*analogs & derivatives. Anal Bioanal Chem. 2012 Jan;402(3):1249-55
fentanyl-BSA conjugate  0   *Serum Albumin, Bovine Fentanyl/*analogs & derivatives. J Immunoassay Immunochem 2005;26(4):285-93
cis-fluoro-ohmefentanyl  0   Fentanyl/*analogs & derivatives. Pharmazie. 2003 May;58(5):300-2
A3080  0   Fentanyl/*analogs & derivatives. J S Afr Vet Assoc 2001 Mar;72(1):29-32
OHM10579  0   Fentanyl/*analogs & derivatives. Pharmacol Biochem Behav 1998 Jul;60(3):665-75
OHM 3507  0   Fentanyl/*analogs & derivatives. Pharmacol Biochem Behav 1998 Feb;59(2):295-303
iodoaminocarfentanil  0   Fentanyl/*analogs & derivatives. Nucl Med Biol 1994 Feb;21(2):231-8
OHM 3295  0   Fentanyl/*analogs & derivatives. Int J Immunopharmacol 1994 Oct;16(10):835-44
norfentanyl  1609-66-1   Fentanyl/*analogs & derivatives. Anesth Analg 1993 Mar;76(3):618-21
despropionylfentanyl  21409-26-7   Fentanyl/*analogs & derivatives. Anesth Analg 1993 Mar;76(3):618-21
benzylfentanyl  1474-02-8   Fentanyl/*analogs & derivatives. J Anal Toxicol 1992 Jan-Feb;16(1):36-41
mirfentanil  117523-47-4 2-Furancarboxamide, N-(1-(2-phenylethyl)-4-piperidinyl)-N-pyrazinyl  Fentanyl/*analogs & derivatives. Life Sci 1991;48(23):PL-111
MS 28  117523-45-2 2-Furancarboxamide, N-(4-methyl-2-pyridinyl)-N-(1-(2-phenylethyl)-4-piperidinyl)  Fentanyl/*analogs & derivatives. Life Sci 1991;48(23):PL-111
4-methoxymethylfentanyl  60618-49-7   Fentanyl/*analogs & derivatives. J Comput Aided Mol Des 1987;1(1):53
R 32557  60644-99-7   Fentanyl/*analogs & derivatives. Yao Hsueh Hsueh Pao 1987;22(11):864
R 32767  60645-01-4   Fentanyl/*analogs & derivatives. Yao Hsueh Hsueh Pao 1987;22(11):864
N-(3-methyl-1-(2-(1,2,3,4-tetrahydro)naphthyl)-4-piperidinyl)-N-phenylpropanamide  97220-08-1   Fentanyl/*analogs & derivatives. J Pharm Sci 1985;74(11):1147
noralfentanil  61086-18-8   Fentanyl/*analogs & derivatives. Anesthesiology 1985;63(6):684
3-methylfentanyl isothiocyanate  101472-20-2   Fentanyl/*analogs & derivatives. Proc Natl Acad Sci USA 1985;82(15):4974
immobyl  63697-78-9   *Azaperone *Fentanyl Drug Combinations. Res Vet Sci 1985;38(2):179
fentanyl isothiocyanate  85951-63-9 Propanamide, N-(1-(2-(4-isothiocyanatophenyl)ethyl)-4-piperidinyl)-N-phenyl  *Isothiocyanates Fentanyl/*analogs & derivatives. FEBS Lett 1982;150(1):125
F 7302  78995-14-9   Fentanyl/*analogs & derivatives.
Pharma Action Analgesics 		Chung Kuo Yao Li Hseuh Pao 1982;17(9):662
lofentanil  60645-00-3   Fentanyl/*analogs & derivatives.
Pharma Action Analgesics, Opioid 		Pain 1982;12(4):343
3-allylfentanyl  82208-84-2 Propanamide, N-phenyl-N-(1-(2-phenylethyl)-3-(2-propenyl)-4-piperidinyl)-, monohydrochloride, cis  Fentanyl/*analogs & derivatives. J Pharm Pharmacol 1982;34(3):210
alpha-methylfentanyl  79704-88-4   Fentanyl/*analogs & derivatives Street Drugs Designer Drugs. J Psychoact Drugs 1981;13(1):91
3-methylfentanyl  42045-86-3   Fentanyl/*analogs & derivatives.
Pharma Action Analgesics 		Sci Sin 1981;24(5):710
demethylfentanyl  61086-23-5 ethanone, 1-(4-(phenylamino)-1-(2-phenylethyl)-4-piperidinyl)  Fentanyl/*analogs & derivatives. Drug Metab Dispos 1980;8(6):425
carfentanil  59708-52-0 4-Piperidinecarboxylic acid, 4-((1-oxopropyl)phenylamino)-1-(2-phenylethyl)-, methyl ester, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)  Fentanyl/*analogs & derivatives Carbon Radioisotopes.
Pharma Action Analgesics, Opioid 		Vet Rec 104(4):64;1978
Innovar  8067-59-2 N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide. 2-hydroxy-1,2,3-propanetricarboxylate mixt. with 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6- tetrahydro-4-pyridinyl)-1,3-dihydro-2H-benzimidazol- 2-one  *Droperidol *Fentanyl.
Pharma Action Analgesics ; Anesthetics, Combined 		Anesteziol Reanimatol 4:24;1978; Anesth Analg (Cleve) 1980;59(1):50; Can Anaesth Soc J 26(1):29;1979; Ill Med J 140(3):214;1971; Jpn J Anesthesiol 20(10):965;1071; Jpn J Anesthesiol 20(10):973;1971; Masui 28(4):356;1979; Rev Esp Anestesiol Reanim 23(5):390;1976; West Afr J Pharmacol Drug Res 2(1):73;1975; Z Gastroenterol 16(11):696;1978INNOVAR; FENTANYL CITRATE AND DROPERIDOL
Hypnorm  52869-98-4 N-phenyl-N-(1-(2-phenylethyl)-4-piperidinylpropanamide mixt. with 1-(4-fluorophenyl)-4-(4-(2- methoxyphenyl)-1-piperazinyl)-1-butanone  *Butyrophenones *Fentanyl Drug Combinations. Br J Cancer 38(6):725;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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