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Fluocinolone Acetonide

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Definition: A glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)     
Pharmacological Action Anti-Inflammatory Agents; Glucocorticoids
Examples Fluocinonide 		Other names Fluortriamcinolone Acetonide; Capex; Bioglan Brand of Fluocinolone Acetonide; Alvadermo; Allergan Brand of Fluocinolone Acetonide; Synalar HP; FS, Derma-Smooth; Derma Smooth FS; Co Fluocin; Acetonide, Fluortriamcinolone; Acetonide, Fluocinolone; medphano Brand of Fluocinolone Acetonide; Yamanouchi Brand of Fluocinolone Acetonide; Syntex Brand of Fluocinolone Acetonide; Synemol; Synamol; Synalar-HP; Smaller Brand of Fluocinolone Acetonide; Septa Brand of Fluocinolone Acetonide; Savage Brand of Fluocinolone AcetonideDrugs* : DERMOTIC; FLUOCINOLONE ACETONIDE; TRI-LUMA; FLUOCET; SYNALAR; DERMA-SMOOTHE/FS; CAPEX; SYNALAR-HP; RETISERT; FLUONID; FLUOTREX
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-chlorofluocinolone acetonide 21-acetate  99339-99-8 Pregna-1,3,5-trien-20-one, 21-(acetyloxy)-3-chloro-6,9-difluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)  Fluocinolone Acetonide/*analogs & derivatives. Steroids 1983;42(4):409
3-chlorofluocinolone acetonide  87138-77-0 Pregna-1,3,5-trien-20-one, 3-chloro-6,9-difluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)  Fluocinolone Acetonide/*analogs & derivatives. Steroids 1983;42(4):409
fluocinolone  807-38-5   Fluocinolone Acetonide/*analogs & derivatives. Fortschr Med 1982;100(34):1573
Butecort  38965-31-0 Pregna-1,4-diene-3,20-dione, 21-(3,3-dimethyl-1-oxobutoxy)-6,9-difluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)  Fluocinolone Acetonide/*analogs & derivatives Ointments. Przegl Dermatol 1981;68(2):155
Synalar-C  53262-68-3   *Fluocinolone Acetonide *Clioquinol Drug Combinations Ointments. E Afr Med J 1981;58(5):360
fluocinolone-neomycin combination  8025-20-5   *Fluocinolone Acetonide *Neomycin Drug Combinations. Otolaryngol Pol 31(5):511;1977NEO-SYNALAR
flunisolide  3385-03-3 6 alpha-fluoro-11 beta,16 alpha,17,21- tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16, 17-acetal with acetone  Fluocinolone Acetonide/*analogs & derivatives.
Pharma Action Anti-Inflammatory Agents ; Anti-Asthmatic Agents 		Ann Allergy 38(6):408;1977; Ann Allergy 41(3):145;1978; Ann Allergy 42(2):80;1979; Ann Allergy 42(3):139;1979; Arch Otolaryngol 1979;105(11):649; Br J Dis Chest 1980;74(1):32; Br Med J 2(6182):95;1979; Can Med Assoc J 119(4):334;1978; Clin Allergy 1980;10(1):65; Clin Allergy 8(4):313;1978; Clin Allergy 9(1):17;1979; Clin Pharmacol Ther 1980;27(3):402; Curr Med Res Opin 6(1):62;1979; Drug Metab Dispos 7(2):81;1979; J Allergy Clin Immunol 1980;65(1):41; J Allergy Clin Immunol 58(5):597;1976; J Allergy Clin Immunol 59(4):287;1977NASALIDE; FLUNISOLIDE; AEROBID; NASAREL; AEROSPAN HFA

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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