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Formaldehyde

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Definition: A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)     
Pharmacological Action Fixatives; Disinfectants
Examples Formocresols 		Other names Methanal; Formol; Formalin; Oxomethane
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Formaldehyde poisoning  0   *Respiratory Hypersensitivity Formaldehyde/adverse effects.
thioformaldehyde  0   Formaldehyde/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Jan;69(1):27-32
2-formyl-1,4-DHP  0   *Pyrans Formaldehyde/*analogs & derivatives. J Org Chem. 2006 Nov 24;71(24):9114-27
resorcinol-formaldehyde resin  0   *Formaldehyde *Resorcinols Root Canal Filling Materials. J Endod 2003 Jul;29(7);435-7
lymph node revealing solution  0   *Ethanol *Ether, Ethyl *Formaldehyde *Acetic Acid. Pathol Oncol Res 1999;5(1):70-2
formalin mercuric chloride acid solution  0   *Formaldehyde *Mercuric Chloride Solutions. Pathol Res Pract 1994 Dec;190(12):1149-61
2-formyl-2H-pyran  0   *Pyrans Formaldehyde/*analogs & derivatives. Chem Res Toxicol 1994 Jul-Aug;7(4):534-43
gelatin-resorcin-formaldehyde-glutaraldehyde adhesive  0   *Formaldehyde *Gelatin *Glutaral *Resorcinols Drug Combinations. Ann Thorac Surg 1993 Oct;56(4):910-5
formaldehyde hydrazone  6629-91-0   *Hydrazones Formaldehyde/*analogs & derivatives. Carcinogenesis 1988;9(1):65
phenoaldehyde  68812-80-6   *Cresols *Formaldehyde *Resorcinols Drug Combinations Resins, Synthetic Root Canal Filling Materials. Oral Surg Oral Med Oral Pathol 1986;62(4):441
formaldehyde-hydroquinone polymer  26353-95-7   *Polymers *Formaldehyde *Hydroquinones. J Appl Biochem 1985;7(2):145
periodate-lysine-paraformaldehyde  0   *Formaldehyde *Lysine *Periodic Acid. Acta Pathol Microbiol Immunol Scand A 1985;93(4):165
camphor, formaldehyde, para-chlorophenol drug combination  0   *Camphor *Chlorophenols *Formaldehyde Drug Combinations. Aust Dent J 1984;29(4):249
formaldehyde-serum albumin receptor  0   *Receptors, Albumin Formaldehyde Serum Albumin, Bovine. J Biol Chem 1985;260(1):53
formaldehyde-serum albumin  0   *Formaldehyde *Serum Albumin, Bovine. J Biol Chem 1985;260(1):53
Toxavit  0   *Formaldehyde *Polymers Dental Pulp Devitalization. Dtsch Zahnarztl Z 1984;39(5):371
formol sublimate  0   *Formaldehyde *Mercuric Chloride. J Clin Pathol 1984;37(6):639
Orth solution  0   *Formaldehyde *Potassium Dichromate. Folia Biol (Praha) 1983;29(6):429
Parmetol A23  61840-41-3   *Formaldehyde. Mutat Res 1983;124(3-4):241
glokill 77  56996-62-4   *Formaldehyde. Mutat Res 1983;124(3-4):241
Germekil  0   *Quaternary Ammonium Compounds *Formaldehyde. Rev Inst Med Trop Sao Paulo 1982;24(5):263
SPAD  58319-09-8   *Formaldehyde *Polymers *Resorcinols Root Canal Filling Materials. Br Dent J 1982;152(2):37
gigasept  58693-20-2   *Formaldehyde *Furans Drug Combinations. Zentralbl Bakteriol (B) 1981;172(6):520
FR dental filling  57017-83-1 FR (dental material)  *Barium Sulfate *Calcium Hydroxide *Formaldehyde *Guaiacol *Zinc Oxide Drug Combinations Root Canal Filling Materials. Shikwa Gakuho 1980;80(10):1471
urea formaldehyde foam  64869-57-4   *Urea *Formaldehyde Construction Materials Polymers. JAMA 1981;245(3):243
Riebler's paste  0   *Formaldehyde *Resorcinols Drug Combinations Root Canal Filling Materials. J Endodont 1980;6(10:784
4-toluenesulfonamide-formaldehyde resin  25035-71-6   *Sulfonamides Formaldehyde/*analogs & derivatives Toluene/*analogs & derivatives Resins, Synthetic. Cutis 1980;26(6):588
gelatin-resorcinol-formaldehyde tissue adhesive  0   *Formaldehyde *Gelatin *Resorcinols Drug Combinations.
Pharma Action Tissue Adhesives 		Z Exp Chir 1980;13(1):43
polyvinyl alcohol formaldehyde foam  26876-25-5   *Formaldehyde *Polyvinyl Alcohol.
Pharma Action Hemostatics 		Helv Chir Acta 1980;47(1-2):163
Bouin's solution  37330-50-0 Acetic acid, mixt. with formaldehyde and 2,4,6-trinitrophenol  *Formaldehyde *Picrates *Acetic Acid.
Pharma Action Fixatives 		Lab Invest 1980;43(2):191
sodium acetate-formalin fixative  0   *Sodium Acetate Formaldehyde/*analogs & derivatives. Am J Med Technol 1980;46(6):459
merthiolate-iodine-formalin fixative  78249-63-5 Mercurate(1-), ethyl(2-mercaptobenzoato(2-)-O,S)-, sodium, mixt. with formaldehyde and iodine  *Formaldehyde *Iodine *Thimerosal. Am J Med Technol 1980;46(6):459
alcoformol  37328-90-8 Formaldehyde, mixt. with ethanol  *Formaldehyde. Oral Surg 47(5):471;1979; Oral Surg 47(5):475;1979
Parker's fluid  0   *Alcohols *Formaldehyde. Klin Oczna 81(1):67;1979; Klin Oczna 81(1):71;1979
phenol-formaldehyde resin  9003-35-4   *Formaldehyde *Phenols *Polymers Membranes, Artificial Resins, Synthetic. Arch Environ Health 30(12):574;1975; Contact Dermatitis 1(4):268;1975; Gig Sanit 1981;(10):19
tricresolformalin  9016-83-5 methylphenol, polymer with formaldehyde  *Cresols Formaldehyde/*analogs & derivatives. Br Dent J 142(2):52;1977; Stomatologie (Bucur) 22(4):263;1975
corticosteroid methanetriol mixture  0   *Dexamethasone *Formaldehyde *Hydrocortisone Drug Combinations Thymol/*analogs & derivatives Root Canal Filling Materials.
Pharma Action Dental Materials 		Czas Stomatol 28(11):1051;1975; ZWR 85(20):937;1976; ZWR 86(3):116;1977
nelex  62929-01-5   *Formaldehyde *Arylsulfonic Acids. Mykosen 16(12):403;1973
Cervisol  8055-05-8   *Iron *Picrates *Formaldehyde Drug Combinations. Ginekol Pol 45(4):481;1972; Pol Tyg Lek 30(36):1477;1975
N2 Dental Cement  8068-83-5 2-methoxy-4-(2-propenyl)phenol, mixt. with zinc oxide  *Eugenol *Formaldehyde *Zinc Oxide Drug Combinations Dental Cements Root Canal Filling Materials.
trilead tetroxide formalin  12287-01-3 (carbonato(2-))dioxotrilead  *Organometallic Compounds Formaldehyde/*analogs & derivatives Lead. J Tokyo Dent Coll Soc 71(10):2096;1971
paraform  30525-89-4   *Formaldehyde *Polymers.
Pharma Action Anti-Infective Agents, Local ; Fixatives 		Cancer Res 1979;39(9):3519; Cutis 22(6):655;1978; Histochemistry 1980;65(2):93
Negatan  9011-02-3   *Cresols *Formaldehyde Drug Combinations. Actas Dermosifiliogr 1979;70(5-6):353; Arzneim Forsch 26(1):96;1976; Ginekol Pol 49(1):51;1978; Gynecologie 30(1):82;1979; Hospitals 77(4):1375;1970; MMW 117(46):1857;1975; Przegl Lek 33(9):824;1976; ZFA 1980;56(4):284

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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