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Tegafur

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Definition: Congener of FLUOROURACIL with comparable antineoplastic action. It has been suggested especially for the treatment of breast neoplasms.     
Pharmacological Action Antimetabolites, Antineoplastic 		Other names FT 207; Bristol Myers Squibb Brand of Tegafur; Utefos; Uftoral; Sunfural S; Prasfarma Brand of Tegafur; N1-(2'-Tetrahydrofuryl)-5-fluorouracil; Futraful; Ftorafur; Fluorofur; Florafur; FT207; FT-207; Bristol-Myers Squibb Brand of Tegafur; Almirall Brand of Tegafur; 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedi; 1-(Tetrahydro-2-furanyl)-5-fluorouracil; 1-(2-Tetrahydrofuryl)-5-fluorouracil
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FCD combination  0   *Tegafur *Pyridines. Toxicology 2006 Jan 16;217(2-3):233-9
TEGAFOX protocol  0   Uracil *Antineoplastic Combined Chemotherapy Protocols Leucovorin Tegafur Organoplatinum Compounds. Br J Cancer. 2006 Jan 16;94(1):69-73
UFT(R) drug  0   *Tegafur *Uracil Drug Combinations.
Pharma Action Antineoplastic Agents 		Dig Dis Sci 1995 Nov;40(11):2434-7
FP protocol  0   Uracil *Antineoplastic Combined Chemotherapy Protocols Cisplatin Tegafur. Gan To Kagaku Ryoho 1995 Mar;22(4):515-20
S 1 (combination)  150863-82-4   *Tegafur *Oxonic Acid Drug Combinations.
Pharma Action Antimetabolites, Antineoplastic 		Gan To Kagaku Ryoho 1993 Jan; 20(1):10-18
VAU regimen  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Tegafur Uracil Vinblastine. Cancer Chemother Pharmacol 1992;30(6):477-9
MVMF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Tegafur Methotrexate Vincristine Mitomycin. Jpn J Clin Oncol 1991;21(5):334
PMUE protocol  0   Uracil *Antineoplastic Combined Chemotherapy Protocols Cisplatin Etoposide Tegafur Mitomycin. Gan To Kagaku Ryoho 1990;17(12):2381
FEPA protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Doxorubicin Etoposide Tegafur Uracil. Gan To Kagaku Ryoho 1989;16(10):3393
COPU protocol  0   Uracil *Antineoplastic Combined Chemotherapy Protocols Cisplatin Cyclophosphamide Tegafur Vincristine. Chung Hua Chung Liu Tsa Chih 1989;11(1):47
BMFt protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Tegafur Methotrexate. Eur J Gynaecol Oncol 1989;10(4):271
CMU protocol  0   Tegafur *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Methotrexate Uracil/analogs & derivatives. Cancer 1989;63(9):1668
FAP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Doxorubicin Tegafur Uracil. Gan To Kagaku Ryoho 1988;15(11):3073
FEP protocol  0   Tegafur *Antineoplastic Combined Chemotherapy Protocols Cisplatin Etoposide Uracil. Gan To Kagaku Ryoho 1988;15(11):3073
MQF-OK-FT protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carbazilquinone Fluorouracil Tegafur Picibanil Mitomycin. Gan To Kagaku Ryoho 1988;15(7):2065
MQF-OK-UFT protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carbazilquinone Fluorouracil Tegafur Mitomycins Picibanil Uracil. Gan To Kagaku Ryoho 1988;15(7):2065
ACFT protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Doxorubicin Tegafur Tamoxifen. Gan To Kagaku Ryoho 1988;15(5):1711
PMU protocol  0   Uracil *Antineoplastic Combined Chemotherapy Protocols Cisplatin Tegafur Mitomycin. Gan To Kagaku Ryoho 1988;15(4 Pt 1):655
ACFM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Doxorubicin Tegafur Methotrexate. Cancer Chemother Pharmacol 1984;13(2):95
ACF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Doxorubicin Tegafur. Cancer Chemother Pharmacol 1984;13(2):95
UFTM protocol  0   Uracil Tegafur *Antineoplastic Combined Chemotherapy Protocols Mitomycin. Gan To Kagaku Ryoho 1984;11(3 pt 2):769
FAM II protocol  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Tegafur Mitomycin. Jpn J Clin Oncol 1984;14(1):3
FACP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Cyclophosphamide Doxorubicin Tegafur. J Clin Oncol 1984;2(3):207
AFC regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Doxorubicin Tegafur. Cancer Chemother Pharmacol 1983;11 Suppl:S89
UFD 1 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Tegafur/analogs & derivatives Uracil. Gan To Kagaku Ryoho 1982;9(4):674
1-UFT protocol  0   Uracil *Antineoplastic Combined Chemotherapy Protocols Tegafur. Arzneimittelforsch 1981;31(8):1268
dehydroftorafur  68723-23-9   Tegafur/*analogs & derivatives. Cancer Treat Rep 1981;65(1-2):69
3-FT  63901-83-7   *Tegafur Isomerism. J Chromatogr 1980;188(1):270
FD 1  62987-05-7 5-fluoro-1,3-bis(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione  Tegafur/*analogs & derivatives. J Chromatogr 157:321;1978; J Med Chem 21(8):738;1978; J Pharm Soc Jpn 98(4):525;1978; JNCI 63(2):456;1979; Nippon Gan Chiryo Gakkai Shi 14(2):129;1979; Recent Results Cancer Res 1980;70;133

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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