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Fumarates

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Definition: Compounds based on fumaric acid.  for esters add ESTERS (NIM)    Other names Fumaric Acid Esters; Esters, Fumaric Acid; Esters, Fumarate; Acid Esters, Fumaric; Fumarate Esters
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
isopropyl 4-oxo-4-(2-oxopyrrolidin-1-yl)-2-butenoate  0   *Fumarates *Pyrrolidinones NF-kappa B/antagonists & inhibitors. BMB Rep 2011 Jul;44(7):468-72
polydiisopropyl fumarate  0   *Fumarates *Polymers. J Tissue Eng Regen Med 2008 Jan;2(1):33-42
4-oxo-4-(2-oxooxazolidin-3-yl)but-2-enoic acid ethyl ester  0   *Fumarates *Oxazolidinones. Int Immunopharmacol 2010 Feb;10(2):163-8
poly(ethylene glycol fumarate-co-hexamethylene carbonate-fumarate)  0   *Fumarates *Polyethylene Glycols. Conf Proc IEEE Eng Med Biol Soc 2006;1() (dup#2):791-4
dimethyl bromomethylfumarate  0   *Fumarates *Hydrocarbons, Brominated. J Org Chem 2007 Jun 22;72(13):4837-43
sodium stearyl fumarate  0   *Fumarates. J Pharm Biomed Anal 2006 Mar 3;40(4):971-4
N-(4,6-dimethylpyrimidin-2-yl)-4-(2-(4-methoxy-3-methylphenyl)-5-(4-methylpiperazin-1-yl)-4,5,6,7-tetrahydro-1H-indol-1-yl)benzenesulfonamide difumarate  0   *Fumarates *Indoles *Sulfonamides. Eur J Pharmacol. 2006 Jul 10;541(1-2):106-14
N-((4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)methyl)-2-(2-(((4-methoxy-2,6-dimethylphenyl) sulfonyl)methylamino)ethoxy)-N-methylacetamide, fumarate  0   *Acrylamides *Fumarates. J Pharmacol Exp Ther. 2006 Jul;318(1):195-205
N-((3R)-1-((6-fluoro-2-naphthyl)methyl)pyrrolidin-3-yl)-2-(1-((5-hydroxy-3-methylpyridin-2-yl)carbonyl)piperidin-4-ylidene)-acetamide hemifumarate  0   *Fumarates *Naphthalenes *Piperidines. J Pharmacol Exp Ther. 2006 Apr;317(1):244-50
methyl hydrogen fumarate  0   *Fumarates. Arch Dermatol Res 2005 Oct;297(4):170-6
poly(ethylene glycol fumarate)  0   *Fumarates *Polyethylene Glycols. Biomaterials. 2006 Feb;27(6):832-41
poly(epsilon-caprolactone fumarate)  0   *Fumarates *Polyesters. Biomaterials. 2006 Feb;27(6):832-41
bis(N-cyclobutylmethylmorphinan)fumarate  0   *Fumarates *Morphinans Receptors, Opioid, mu/antagonists & inhibitors Receptors, Opioid, mu/agonists Receptors, Opioid, kappa/agonists. J Pharmacol Exp Ther 2005 Nov;315(2):821-7
calcium fumarate  0   *Fumarates Calcium. Boll Chim Farm. 2003 Sep;142(7):258-9
2-(2-(1-benzylpiperidin-4-yl)ethyl)-2,3-dihydro-9-methoxy-1H-pyrrolo(3,4-b)quinolin-1-one hemifumarate  0   *Fumarates *Quinolines. Eur J Pharmacol. 2003 Mar 28;465(1-2):97-103
poly(fumaric-co-sebacic acid)  0   *Decanoic Acids *Fumarates *Polymers Biocompatible Materials. Biomaterials 2002 Nov;23(22):4413-23
AS-9705  219622-61-4   *Azepines *Fumarates. Arzneimittelforschung 2003;53(2):98-106
fumarylacetone  0   *Fumarates Acetone/*analogs & derivatives. Adv Exp Med Biol 2001;500:339-42
fumaric acid, triethanolamine salt  0   *Fumarates. Dokl Biochem Biophys 2001 Jul-Aug;379:294-6
Polypropylene fumarate-phloroglucinol triglycidyl methacrylate  0   *Fumarates *Methacrylates *Polypropylenes Bone Cements. Biomaterials 2001 Oct;22(20):2749-57
aliskiren  0   *Amides *Fumarates Antihypertensive Agents Renin/antagonists & inhibitors. Hypertension 2002 Jan;39(1):E1-8AMTURNIDE; TEKTURNA HCT; TEKTURNA; VALTURNA; TEKAMLO
acetoxymethyl N(3)-(4-methoxyfumaroyl)-2,3-diaminopropanoate  0   *Fumarates beta-Alanine/*analogs & derivatives. Microbiology 2001 Jul;147(Pt 7):1955-9
1-(2-(3,4-dihydro-6,7-dimethyl-2-naphthalenyl)ethyl) pyrrolidine fumarate  0   *Fumarates *Naphthalenes. Life Sci 2001 Aug 24;69(14):1691-7
5-(4-methylpiperazin-1-yl)-8-chloro-pyrido(2,3)(1,5)benzoxazepine fumarate  0   *Fumarates *Oxazepines *Piperazines. J Pharm Pharmacol 2001 Mar;53(3):317-21
3,6-bis(N-fumaryl-N(n-butyl)amino)-2,5-diketopiperazine  0   *Fumarates *Piperazines. J Pharm Sci 2000 Jul;89(7):867-75
strobilurin P  0   *Fumarates *Heterocyclic Compounds, 2-Ring Methacrylates Electron Transport Complex III. J Antibiot (Tokyo) 2000 Mar;53(3):297-300
strobilurin O  0   *Fumarates *Heterocyclic Compounds, 2-Ring Methacrylates Electron Transport Complex III. J Antibiot (Tokyo) 2000 Mar;53(3):297-300
fumaryl chloride  627-63-4   *Fumarates. Sprectrochim Acta A Mol Biomol Spectrosc 2000 Jan;56A(1):157-65
LU 111995  0   *Fumarates *Quinazolines. J Pharmacol Exp Ther 1999 Jul;290(1):146-52
4-nitrophenyl fumarate  0   *Fumarates *Nitrobenzenes. Bioorg Med Chem 1999 Jan;7(1):83-91
fumaric acid semialdehyde ethyl ester  0   *Fumarates Aspartate Ammonia-Lyase/antagonists & inhibitors. Arch Biochem Biophys 1997 May 15;341(2):329-36
schizostatin  0   *Fatty Acids *Fumarates Farnesyl-Diphosphate Farnesyltransferase/antagonists & inhibitors. J Antibiot (Tokyo) 1996 Jul;49(7):617-23
benzylfumaric acid  0   *Benzyl Compounds *Fumarates. Appl Environ Microbiol 1996 Mar;62(3):974
poly(propylene fumarate)  0   *Fumarates *Polypropylenes Bone Cements. J Biomed Mater Res 1995 Oct;29(10):1241-7
fumaroyl bis(methylphosphate)  144577-06-0   *Fumarates *Phosphoric Acid Esters Hydroxybutyrate Dehydrogenase/antagonists & inhibitors. Bioorg Med Chem 1994 Jun;2(6):379-85
fumaric acid, monooctadecyl ester, sodium salt  4070-80-8   *Fumarates *Stearates Excipients. Pharm Acta HeLv 1992;67(2):50-6
citraconic acid  498-23-7   *Fumarates *Maleates. J Invest Dermatol 1993 Jul;101(1):37-42
ethyl fumarate  2459-05-4   *Fumarates Psoriasis.
Pharma Action Dermatologic Agents 		Adv Exp Med Biol 1989;252:265
2-chlorofumaric acid  617-43-6   *Fumarates. Biol Chem Hoppe Seyler 1989;370(6):601
fumaryldithranol  125379-01-3   *Fumarates Anthralin/*analogs & derivatives Glucosephosphate Dehydrogenase/antagonists & inhibitors. Pharm Acta Helv 1988;63(12):322
fumaronitrile  764-42-1   *Fumarates. J Appl Toxicol 1988;8(3):201
N(3)-(4-methoxyfumaroyl)-2,3-diaminopropionic acid  96920-07-9   *Fumarates beta-Alanine/*analogs & derivatives Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/antagonists & inhibitors. Biochemistry 1988;27(7):2282
poly(propylenefumarate) methylmethacrylate  116589-63-0   *Fumarates *Methylmethacrylates Bone Cements. J Orthop Res 1988;6(4):585
dimethyl fumarate  624-49-7   *Fumarates.
Pharma Action Dermatologic Agents ; Immunosuppressive Agents ; Radiation-Sensitizing Agents 		Radiat Res 1988;114(2):215
N(beta)-fumarylcarboxyamido-2,3-diaminopropionic acid  91235-43-7 L-Alanine, 3-((4-amino-1,4-dioxo-2-butenyl)amino)-, (E)  *Fumarates beta-Alanine/*analogs & derivatives. Biochem Biophys Res Commun 1984;120(3):865
diethyl fumarate  623-91-6   *Fumarates. Chem Biol Interact 1982;40(3):365
2,3-difluorofumaric acid  2714-32-1 2-Butenedioic acid, 2,3-difluoro-, (E)  *Fumarates. Biochemistry 1982;21(11):2637
2-fluorofumarate  672-18-4   *Fumarates. Biochemistry 1982;21(11):2637
bromomesaconic acid  32319-83-8   *Fumarates. Biochim Biophys Acta 1981;662(2):196
fumaric acid  110-17-8   *Fumarates. Biochem Exp Biol 1980;16(3):265
fumarprotocetraric acid  489-50-9   *Fumarates Allergens. Contact Dermititis 1980;6(2):111
2-(5'-phenylpentyl)fumaric acid  71033-47-1 2-Butenedioic acid, 2-(5-phenylpentyl)-, (E)  *Fumarates. Biochem J 177(1):115;1979
dihydroxyfumarate  133-38-0   *Fumarates. Acta Biol Med Ger 36(5/6):731;1977; Biochem Biophys Res Commun 1979;89(4):1239; Biochem J 163:441;1977; J Invest Dermatol 61(2):55;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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